• Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs 

      Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Yassin, Mohammed Ahmed Alamin Yousif; Dongre, Harsh Nitin; Costea, Daniela Elena; Tangl, Stefan; Stavropoulos, Andreas; Bolstad, Anne Isine; Suliman, Salwa; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-11-30)
      Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative ...
    • Influence of Bone Substitutes on Mesenchymal Stromal Cells in an Inflammatory Microenvironment 

      Shanbhag, Siddharth; Rana, Neha; Suliman, Salwa; Idris, Shaza Bushra Mohamed; Mustafa, Kamal Babikeir Elnour; Stavropoulos, Andreas (Journal article; Peer reviewed, 2022)
      Bone regeneration is driven by mesenchymal stromal cells (MSCs) via their interactions with immune cells, such as macrophages (MPs). Bone substitutes, e.g., bi-calcium phosphates (BCPs), are commonly used to treat bone ...
    • Spheroid Coculture of Human Gingiva-Derived Progenitor Cells With Endothelial Cells in Modified Platelet Lysate Hydrogels 

      Shanbhag, Siddharth; Elsebahy, Ahmad Rashad; Helgeland Nymark, Ellen; Suliman, Salwa; Davies, Catharina de Lange; Stavropoulos, Andreas; Bolstad, Anne Isine; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-08-26)
      Cell coculture strategies can promote angiogenesis within tissue engineering constructs. This study aimed to test the angiogenic potential of human umbilical vein endothelial cells (HUVEC) cocultured with gingiva-derived ...
    • Xeno-free spheroids of human gingiva-derived progenitor cells for bone tissue engineering 

      Shanbhag, Siddharth; Suliman, Salwa; Bolstad, Anne Isine; Stavropoulos, Andreas; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2020)
      Gingiva has been identified as a minimally invasive source of multipotent progenitor cells (GPCs) for use in bone tissue engineering (BTE). To facilitate clinical translation, it is important to characterize GPCs in xeno-free ...