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Browsing Bergen Open Research Archive by Author "Svarstad, Einar"

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Now showing items 1-14 of 14

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    • Accumulation of Globotriaosylceramide in Podocytes in Fabry Nephropathy Is Associated with Progressive Podocyte Loss 

      Najafian, Behzad; Tøndel, Camilla; Svarstad, Einar; Gubler, Marie-Claire; Oliveira, Joao-Paulo; Mauer, Michael (Journal article; Peer reviewed, 2020)
      Background In males with classic Fabry disease, the processes leading to the frequent outcome of ESKD are poorly understood. Defects in the gene encoding α-galactosidase A lead to accumulation of globotriaosylceramide (GL3) ...
    • Accuracy of single intravenous access iohexol GFR in children is hampered by marker contamination 

      Eide, Thea Tislevoll; Hufthammer, Karl Ove; Brun, Atle; Brackman, Damien; Svarstad, Einar; Tøndel, Camilla (Journal article; Peer reviewed, 2021)
      Measurement of glomerular filtration rate (GFR) in children by iohexol injection and blood sampling from the contralateral arm is widely used. A single intravenous access for iohexol injection and subsequent blood sampling ...
    • Addition of eGFR and age improves the prognostic absolute renal risk-model in 1,134 norwegian patients with IgA nephropathy 

      Knoop, Thomas; Vågane, Ann Merethe; Vikse, Bjørn Egil; Svarstad, Einar; Magnusdottir, Bergrun Tinna; Leh, Sabine Maria; Reisæter, Anna Varberg; Bjørneklett, Rune (Peer reviewed; Journal article, 2015-05)
      Background: Predicting outcome in individual patients with IgA nephropathy (IgAN) is difficult but important. For this purpose, the absolute renal risk (ARR) model has been developed in a French cohort to calculate the ...
    • Case Report: Polyvinylpyrrolidone deposition disease from repeated injection of opioid substitution drugs: Report of a case with a fatal outcome 

      Stalund, Ida Viken; Riise, Gro Nygard; Leh, Friedemann; Bjånes, Tormod Karlsen; Riise, Lars; Svarstad, Einar; Leh, Sabine (Journal article; Peer reviewed, 2021)
      Background: Intravenous injection of oral opioid substitution drugs (OSD) is widespread among injecting drug users. Several OSDs contain the polymer polyvinylpyrrolidone (PVP) as an excipient. Parenterally administered PVP ...
    • The changing landscape of Fabry disease 

      Svarstad, Einar; Marti, Hans-Peter (Journal article; Peer reviewed, 2020)
    • Developing nephrology services in low income countries: A case of Tanzania 

      Furia, Francis F.; Shoo, Jacqueline; Ruggajo, Paschal Joseph; Kilonzo, Kajiru; Basu, Gopal; Yeates, Karen; Varughese, Santosh; Svarstad, Einar; Kisanga, Onesmo (Peer reviewed; Journal article, 2019-10-17)
      Background: The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health ...
    • Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative 

      Hughes, Derralynn A.; Aguiar, Patricio; Deegan, Patrick B; Ezgu, Fatih; Frustaci, Andrea; Lidove, Olivier; Linhart, Aleš; Lubanda, Jean-Claude; Moon, James C; Nicholls, Kathleen; Niu, Dau-Ming; Nowak, Albina; Ramaswami, Uma; Reisin, Ricardo; Rozenfeld, Paula; Schiffmann, Raphael; Svarstad, Einar; Thomas, Mark; Torra, Roser; Vujkovac, Bojan; Warnock, David G.; West, Michael L; Johnson, Jack; Rolfe, Mark J; Feriozzi, Sandro (Journal article; Peer reviewed, 2020)
      Objectives The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may ...
    • Elevated Ambulatory Blood Pressure Measurements are Associated with a Progressive Form of Fabry Disease 

      Rossi, Federica; Svarstad, Einar; Elsaid, Hassan; Binaggia, Agnese; Roggero, Letizia; Auricchio, Sara; Marti, Hans-Peter; Pieruzzi, Federico (Journal article; Peer reviewed, 2021)
      Introduction Published data on hypertension incidence and management in Anderson–Fabry disease are scant and the contribution of elevated blood pressure to organ damage is not well recognized. Aim Therefore, we have ...
    • End Stage Renal Disease Predicts Increased Risk of Death in First Degree Relatives in the Norwegian Population 

      Skrunes, Rannveig; Svarstad, Einar; Reisæter, Anna Varberg; Marti, Hans-Petter; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2016-11-09)
      Background: Increased risk of end stage renal disease (ESRD) and death in Norwegian living kidney donors has been reported, most of the donors were related to the recipient. The present study investigates risk of death in ...
    • Low birth weight and risk of progression to end stage renal disease in IgA nephropathy - A retrospective registry-based cohort study 

      Ruggajo, Paschal Joseph; Svarstad, Einar; Leh, Sabine Maria; Marti, Hans-Peter; Reisæter, Anna Varberg; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2016-04-19)
      Background: Low Birth Weight (LBW) is a surrogate for fetal undernutrition and is associated with impaired nephron development in utero. In this study, we investigate whether having been born LBW and/or small for gestational ...
    • Mosaicism of podocyte involvement is related to podocyte injury in females with Fabry disease 

      Mauer, Michael; Glynn, Emily; Svarstad, Einar; Tøndel, Camilla; Gubler, Marie-Claire; West, Michael; Sokolovskiy, Alexey; Whitley, Chester; Najafian, Behzad (Peer reviewed; Journal article, 2014-11-11)
      Background: Fabry disease. an X-linked deficiency of α-galactosidase A coded by the GLA gene, leads to intracellular globotriaosylceramide (GL-3) accumulation. Although less common than in males, chronic kidney disease, ...
    • Polyvinylpyrrolidone deposition disease in patients with intravenous opioid use: a case series 

      Leh, Friedemann; Stalund, Ida Viken; Bjånes, Tormod Karlsen; Ohldieck, Christian; Svarstad, Einar; Leh, Sabine (Journal article; Peer reviewed, 2021)
      The polymer polyvinylpyrrolidone (PVP) is an excipient widely used in prescription drugs. Depending on the molecular weight (MW), parenterally administered PVP may accumulate in various tissues. Consequently, moderate and ...
    • Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease: the European Fabry Working Group consensus document 

      Biegstraaten, Marieke; Arngrímsson, R; Barbey, F; Boks, L; Cecchi, Franco; Deegan, PB; Feldt-Rasmussen, Ulla; Geberhiwot, T; Germain, DP; Hendriksz, C; Hughes, DA; Kantola, I; Karabul, N; Lavery, C; Linthorst, GE; Mehta, A; van de Mheen, E; Oliveira, JP; Parini, R; Ramaswami, Uma; Rudnicki, M; Serra, A; Sommer, Claudia; Sunder-Plassmann, G; Svarstad, Einar; Sweeb, A; Terryn, W; Tylki-Szymanska, A; Tøndel, Camilla; Vujkovac, B; Weidemann, Frank; Wijburg, FA; Woolfson, P; Hollak, CE. (Peer reviewed; Journal article, 2015-05-27)
      Introduction Fabry disease (FD) is a lysosomal storage disorder resulting in progressive nervous system, kidney and heart disease. Enzyme replacement therapy (ERT) may halt or attenuate disease progression. Since administration ...
    • Reduced α-galactosidase A activity in zebrafish (Danio rerio) mirrors distinct features of Fabry nephropathy phenotype 

      Elsaid, Hassan Osman Alhassan; Furriol, Jessica; Blomqvist, Maria; Diswall, Mette; Leh, Sabine; Gharbi, Naouel; Anonsen, Jan Haug; Babickova, Janka; Tøndel, Camilla; Svarstad, Einar; Marti, Hans Peter; Krause, Maximilian (Journal article; Peer reviewed, 2022)
      Fabry disease (FD) is a rare genetic lysosomal storage disorder, resulting from partial or complete lack of alpha-galactosidase A (α-GAL) enzyme, leading to systemic accumulation of substrate glycosphingolipids with a broad ...

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