• The expressed mutational landscape of microsatellite stable colorectal cancers 

      Sveen, Anita; Johannessen, Bjarne; Eilertsen, Ina Andrassy; Røsok, Bård Ingvald; Gulla, Marie; Eide, Peter Andreas Wold; Bruun, Jarle; Kryeziu, Kushtrim; Meza, Leonardo Zepeda; Myklebost, Ola; Bjørnbeth, Bjørn Atle; Skotheim, Rolf I.; Nesbakken, Arild; Lothe, Ragnhild Adelheid (Journal article; Peer reviewed, 2021)
      Background Colorectal cancer is the 2nd leading cause of cancer-related deaths with few patients benefiting from biomarker-guided therapy. Mutation expression is essential for accurate interpretation of mutations as ...
    • Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains 

      Berg, Kaja Christine Graue; Sveen, Anita; Høland, Maren; Alagaratnam, Sharmini; Rasmussen, Marianne Berg; Danielsen, Stine Aske; Nesbakken, Arild; Søreide, Kjetil; Lothe, Ragnhild A (Peer reviewed; Journal article, 2019-07-15)
      About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, ...