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Blar i Bergen Open Research Archive på forfatter "Sviland, Lisbet"

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    • Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosis infected lungs and lymph node tissues 

      Mustafa, Tehmina; Leversen, Nils Anders; Sviland, Lisbet; Wiker, Harald G. (Peer reviewed; Journal article, 2014-10-03)
      Background: The clinical course of tuberculosis (TB) infection, bacterial load and the morphology of lesions vary between pulmonary and extrapulmonary TB. Antigens expressed in abundance during infection could represent ...
    • Expression Profiling of Major Histocompatibility and Natural Killer Complex Genes Reveals Candidates for Controlling Risk of Graft versus Host Disease 

      Novota, Peter; Zinöcker, Severin; Norden, Jean; Wang, Xiao Nong; Sviland, Lisbet; Opitz, Lennart; Salinas-Riester, Gabriela; Rolstad, Bent; Dickinson, Anne M.; Walter, Lutz; Dressel, Ralf (Peer reviewed; Journal article, 2011-01-28)
      Background: The major histocompatibility complex (MHC) is the most important genomic region that contributes to the risk of graft versus host disease (GVHD) after haematopoietic stem cell transplantation. Matching of MHC ...
    • Immunochemistry-Based Diagnosis of Extrapulmonary Tuberculosis: A Strategy for Large-Scale Production of MPT64-Antibodies for Use in the MPT64 Antigen Detection Test 

      Hoel, Ida Marie; Ali, Iman A Mohammed; Ishtiaq, Sheeba; Sviland, Lisbet; Wiker, Harald Gotten; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)
      Tuberculosis (TB) is a global health problem. The immunohistochemistry (IHC)-based MPT64 antigen detection test has shown promising results for diagnosing extrapulmonary TB in previous studies. However, the anti-MPT64 ...
    • Immunocytochemical detection of Mycobacterium Tuberculosis complex specific antigen, MPT64, improves diagnosis of tuberculous lymphadenitis and tuberculous pleuritis 

      Tadele, Agerie; Beyene, Demissew Balcha; Hussein, Jemal; Gemechu, Tuffa; Birhanu, Asaye; Mustafa, Tehmina; Tsegaye, Aster; Aseffa, Abraham; Sviland, Lisbet (Peer reviewed; Journal article, 2014-11-25)
      Background: A rapid, sensitive and accurate laboratory diagnosis is of prime importance in suspected extrapulmonary tuberculosis (EPTB) cases. However, traditional techniques for the detection of acid-fast bacilli have ...
    • Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64 

      Purohit, Manju Raj; Mustafa, Tehmina; Wiker, Harald G.; Mørkve, Odd; Sviland, Lisbet (Peer reviewed; Journal article, 2007-09-25)
      Background: The aim of this study was to evaluate the diagnostic potential of immunohistochemistry using an antibody to the secreted mycobacterial antigen MPT64, in abdominal and lymph node tuberculosis. Methods: We used ...
    • In Situ Expression of CD40, CD40L (CD154), IL-12, TNF-a, IFN-g and TGF-b1 in Murine Lungs during Slowly Progressive Primary Tuberculosis 

      Mogga, S. J.; Mustafa, Tehmina; Sviland, Lisbet; Nilsen, Rune (Journal article, 2003-09)
      The distribution and expression of CD40, its ligand CD40L (154) and related cytokines interleukin-12 (IL-12), tumour necrosis factor-α (TNF-α), interferon-γ (IFN-γ) and transforming growth factor-β1 (TGF-β1) were studied ...
    • Increased Bcl-2 and Reduced Bax Expression in Infected Macrophages in Slowly Progressive Primary Murine Mycobacterium tuberculosis Infection 

      Mogga, S. J.; Mustafa, Tehmina; Sviland, Lisbet; Nilsen, Rune (Peer reviewed; Journal article, 2002-10)
      Mycobacterium tuberculosis (MTB) persists in host macrophages (Mφs) because it has developed mechanisms to escape Mφ killing. In vitro studies have shown that MTB can induce and inhibit apoptosis by causing the expression ...
    • MPT64 antigen detection test improves diagnosis of pediatric extrapulmonary tuberculosis in Mbeya, Tanzania 

      Grønningen, Erlend; Nanyaro, Marywinnie; Sviland, Lisbet; Ngadaya, Esther; Muller, William; Torres, Lisete; Mfinanga, Sayoki; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)
      Pediatric extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. A new immunochemistry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study ...
    • Serodiagnosis of tuberculous lymphadenitis using a combination of antigens 

      Beyene, Demissew Balcha; Franken, Kees Lumc; Yamuah, Lawrence; Aseffa, Abraham; Wiker, Harald G.; Kolk, Arend; Engers, Howard; Klatser, Paul R.; Sviland, Lisbet (Peer reviewed; Journal article, 2010)
      Background: The diagnosis of extra-pulmonary tuberculosis (EPTB) by conventional methods such as culture and microscopy has low sensitivity and requires an invasive procedure. A simple rapid serological test would be of ...

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