Browsing Bergen Open Research Archive by Author "Tøndel, Camilla"
Now showing items 1-9 of 9
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Growth Differentiation Factor 15 in Children with Chronic Kidney Disease and after Renal Transplantation
Thorsteinsdottir, Hjørdis; Salvador, Cathrin Lytomt; Mjøen, Geir; Lie, Anine; Sugulle, Meryam; Tøndel, Camilla; Brun, Atle; Almaas, Runar; Bjerre, Anna Kristina (Journal article; Peer reviewed, 2020)Growth differentiation factor 15 (GDF-15) is strongly associated with cardiovascular disease (CVD). The aim of our study was to evaluate plasma and urinary levels of GDF-15 after pediatric renal transplantation (Rtx) and ... -
Live attenuated influenza vaccine in children induces b-cell responses in tonsils
Mohn, Kristin Greve Isdahl; Brokstad, Karl Albert; Pathirana, Rishi; Bredholt, Geir; Jul-Larsen, Åsne; Trieu, Mai Chi; Jalloh, Sarah Larteley Lartey; Montemoli, Emanuele; Tøndel, Camilla; Aarstad, Hans Jørgen; Cox, Rebecca Jane (Peer reviewed; Journal article, 2016)Background. Tonsils play a key role in eliciting immune responses against respiratory pathogens. Little is known about how tonsils contribute to the local immune response after intranasal vaccination. Here, we uniquely ... -
Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children
Mohn, Kristin Greve Isdahl; Bredholt, Geir; Brokstad, Karl Albert; Pathirana, Rishi; Aarstad, Hans Jørgen; Tøndel, Camilla; Cox, Rebecca Jane (Peer reviewed; Journal article, 2015-05-15)Background. The live attenuated influenza vaccine (LAIV) is the preferred vaccine for children, but the mechanisms behind protective immune responses are unclear, and the duration of immunity remains to be elucidated. This ... -
Low birthweight is associated with lower glomerular filtration rate in middle-aged mainly healthy women
Lillås, Bjørn Steinar; Tøndel, Camilla; Assmus, Jörg; Vikse, Bjørn Egil (Journal article; Peer reviewed, 2020)Background Low birthweight (LBW) has been shown to increase the risk of severe kidney disease. Studies have also shown associations between LBW and lower estimated glomerular filtration rate (GFR) in young adults. In this ... -
Markers of nephropathy in young Fabry disease patients; role of kidney biopsies and functional measurements
Tøndel, Camilla (Doctoral thesis; Peer reviewed, 2013-04-05)Backgound: Fabry disease is an X-linked disease affecting glycosphingolipid metabolism due to deficiency of the lysosomal enzyme α-galactosidase. The natural course of the disease is related to progressive accumulation of ... -
Measurement of renal functional response using iohexol clearance—a study of different outpatient procedures
Lillås, Bjørn Steinar; Tøndel, Camilla; Gjerde, Anna; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2019)Background: Glomerular filtration rate (GFR) increases after a heavy protein load; an increase termed renal functional response (RFR). Decreased RFR could be a marker of early kidney damage, but published methods are ... -
Mosaicism of podocyte involvement is related to podocyte injury in females with Fabry disease
Mauer, Michael; Glynn, Emily; Svarstad, Einar; Tøndel, Camilla; Gubler, Marie-Claire; West, Michael; Sokolovskiy, Alexey; Whitley, Chester; Najafian, Behzad (Peer reviewed; Journal article, 2014-11-11)Background: Fabry disease. an X-linked deficiency of α-galactosidase A coded by the GLA gene, leads to intracellular globotriaosylceramide (GL-3) accumulation. Although less common than in males, chronic kidney disease, ... -
The pharmacokinetics, safety, and tolerability of mirabegron in children and adolescents with neurogenic detrusor overactivity or idiopathic overactive bladder and development of a population pharmacokinetic model-based pediatric dose estimation
Rittig, Søren; Baka-Ostrowska, Malgorzata; Tøndel, Camilla; Johan, Vande Walle; Kjaeer, Birgitta; Passier, Paul; Bosman, Brigitte; Stroosma, Otto; Tannenbaum, Stacey (Peer reviewed; Journal article, 2019-10-22)Introduction: Mirabegron, a selective β3-adrenoreceptor agonist, is a well-established alternative to antimuscarinics in adults with overactive bladder (OAB) symptoms and is under development for use in pediatric patients. ... -
Recommendations for initiation and cessation of enzyme replacement therapy in patients with Fabry disease: the European Fabry Working Group consensus document
Biegstraaten, Marieke; Arngrímsson, R; Barbey, F; Boks, L; Cecchi, Franco; Deegan, PB; Feldt-Rasmussen, Ulla; Geberhiwot, T; Germain, DP; Hendriksz, C; Hughes, DA; Kantola, I; Karabul, N; Lavery, C; Linthorst, GE; Mehta, A; van de Mheen, E; Oliveira, JP; Parini, R; Ramaswami, Uma; Rudnicki, M; Serra, A; Sommer, Claudia; Sunder-Plassmann, G; Svarstad, Einar; Sweeb, A; Terryn, W; Tylki-Szymanska, A; Tøndel, Camilla; Vujkovac, B; Weidemann, Frank; Wijburg, FA; Woolfson, P; Hollak, CE. (Peer reviewed; Journal article, 2015-05-27)Introduction Fabry disease (FD) is a lysosomal storage disorder resulting in progressive nervous system, kidney and heart disease. Enzyme replacement therapy (ERT) may halt or attenuate disease progression. Since administration ...