Blar i Bergen Open Research Archive på forfatter "Taxt, Torfinn"

Viser treff 1-5 av 5

    • Image-based assessment of microvascular function and structure in collagen XV- and XVIII-deficient mice 

      Brekke, Cecilie; Løkka, Guro; Heljäsvaara, Ritva; Taxt, Torfinn; Pavlin, Tina; Sormunen, Raija T.; Pihlajaniemi, Taina; Curry, Fitz-Roy E.; Tenstad, Olav; Reed, Rolf K. (Peer reviewed; Journal article, 2014-01)
      Collagen XV and XVIII are ubiquitous constituents of basement membranes. We aimed to study the physiological roles of these two components of the permeability barrier non-invasively in striated muscle in mice deficient in ...

    • Increased microvascular permeability in mice lacking Epac1 (Rapgef3) 

      Kopperud, Reidun Kristin; Rygh, Cecilie Brekke; Karlsen, Tine Veronica; Krakstad, Camilla; Kleppe, Rune; Høivik, Erling Andre; Bakke, Marit; Tenstad, Olav; Selheim, Frode; Liden, Åsa; Madsen, Lise; Pavlin, Tina; Taxt, Torfinn; Kristiansen, K.; Curry, FE; Reed, Rolf K.; Doskeland, Stein Ove (Peer reviewed; Journal article, 2017-02)
      Aim: Maintenance of the blood and extracellular volume requires tight control of endothelial macromolecule permeability, which is regulated by cAMP signalling. This study probes the role of the cAMP mediators rap guanine ...

    • Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas 

      Haldorsen, Ingfrid S.; Stefansson, Ingunn; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Trovik, Jone; Taxt, Torfinn; Akslen, Lars A.; Salvesen, Helga Birgitte (Peer reviewed; Journal article, 2014)
      Background: We aimed to study the angiogenic profile based on histomorphological markers in endometrial carcinomas in relation to imaging parameters obtained from preoperative dynamic contrast-enhanced magnetic resonance ...

    • Lack of functional normalisation of tumour vessels following anti-angiogenic therapy in glioblastoma 

      Obad, Nina; Espedal, Heidi; Jirík, Radovan; Sakariassen, Per Øystein; Rygh, Cecilie Brekke; Lund-Johansen, Morten; Taxt, Torfinn; Niclou, Simone Pierrette; Bjerkvig, Rolf; Keunen, Olivier (Peer reviewed; Journal article, 2017)
      Neo-angiogenesis represents an important factor for the delivery of oxygen and nutrients to a growing tumour, and is considered to be one of the main pathodiagnostic features of glioblastomas (GBM). Anti-angiogenic therapy ...

    • Multimodal imaging of gliomas in the context of evolving cellular and molecular therapies 

      Keunen, Olivier; Taxt, Torfinn; Grüner, Renate; Lund-Johansen, Morten; Tonn, Joerg-Christian; Pavlin, Tina; Bjerkvig, Rolf; Niclou, Simone P.; Thorsen, Frits Alan (Peer reviewed; Journal article, 2014-09-30)
      The vastmajority ofmalignant gliomas relapse after surgery and standard radio-chemotherapy. Novelmolecular and cellular therapies are thus being developed, targeting specific aspects of tumor growth.While histopathology ...