Blar i Bergen Open Research Archive på forfatter "Tiam, Appolinaire"
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18-24-month HIV-free survival as measurement of the effectiveness of prevention of mother-to-child transmission in the context of lifelong antiretroviral therapy: Results of a community-based survey
Tiam, Appolinaire; Gill, Michelle; Machekano, Rhoderick; Tukei, Vincent; Mokone, Majoalane; Viana, Shannon; Letsie, Mosilinyane; Tsietso, Mots'Oane; Seipati, Irene; Khachane, Cecilia; Nei, Marethabile; Mohai, Florence; Tylleskär, Thorkild; Guay, Laura (Journal article; Peer reviewed, 2020)Introduction Population-based HIV-free survival at 18–24 months of age among HIV-exposed infants in high prevalence settings in the era of treatment for all is largely unknown. We conducted a community-based survey to ... -
24-Month HIV-free survival among HIV-exposed Infants in Lesotho: the PEAWIL cohort study
Tukei, Vincent; Machekano, Rhoderick; Gill, Michelle; Tiam, Appolinaire; Mokone, Majoalane; Isavwa, Anthony; Nyabela, Malijane; Mots’oane, Tsietso; Nchephe, Seipati; Letsie, Mosilinyane; Kassaye, Seble G.; Guay, Laura (Journal article; Peer reviewed, 2020)Introduction Following the implementation of the provision of lifelong antiretroviral therapy to all HIV-positive pregnant or breastfeeding women for prevention of mother-to-child transmission (PMTCT) of HIV by the Kingdom ... -
Adverse Pregnancy Outcomes Among HIV-positive Women in the Era of Universal Antiretroviral Therapy Remain Elevated Compared With HIV-negative Women
Tukei, Vincent; Hoffman, Heather J.; Greenberg, Lauren; Thabelo, Ramatlapeng; Nchephe, Masepeli; Mots'oane, Tsietso; Masitha, Matseliso; Chabela, Mammatli; Mokone, Majoalane; Mofenson, Lynne; Guay, Laura; Tiam, Appolinaire (Journal article; Peer reviewed, 2021)Background: Without treatment, HIV infection in pregnant women is associated with adverse pregnancy outcomes. We compared adverse pregnancy outcomes among HIV-positive women on antiretroviral therapy (ART) and HIV-negative ... -
Comparison of 6-week PMTCT outcomes for HIV-exposed and HIV-unexposed infants in the era of lifelong ART: Results from an observational prospective cohort study
Tiam, Appolinaire; Kassaye, Seble G.; Machekano, Rhoderick; Tukei, Vincent; Gill, Michelle M.; Mokone, Majoalane; Letsie, Mosilinyane; Tsietso, Mots'Oane; Seipati, Irene; Barasa, Janety; Isavwa, Anthony; Tylleskär, Thorkild; Guay, Laura (Journal article; Peer reviewed, 2019)Background Lifelong antiretroviral therapy (ART) reduces mother-to-child HIV transmission (MTCT) and improves maternal health. Data on the outcomes of HIV-exposed infants (HEI) compared to their unexposed counterparts in ... -
Conventional early infant diagnosis in Lesotho from specimen collection to results usage to manage patients: Where are the bottlenecks?
Tiam, Appolinaire; Gill, Michelle M; Hoffman, Heather J; Isavwa, Anthony; Mokone, Mafusi; Foso, Matokelo; Safrit, Jeffrey T; Mofenson, Lynne M; Tylleskär, Thorkild; Guay, Laura (Peer reviewed; Journal article, 2017-10-10)Introduction: Early infant diagnosis is an important step in identifying children infected with HIV during the perinatal period or in utero. Multiple factors contribute to delayed antiretroviral treatment initiation for ... -
Integrating pediatric TB services into child healthcare services in Africa: study protocol for the INPUT cluster-randomized stepped wedge trial
Denoeud-Ndam, Lise; Otieno-Masaba, Rose; Tchounga, Boris; Machekano, Rhoderick; Simo, Leonie; Mboya, Joseph Phelix; Kose, Judith; Tchendjou, Patrice; Bissek, Anne-Cécile Zoung-Kanyi; Okomo, Gordon Odhiambo; Casenghi, Martina; Cohn, Jennifer; Tiam, Appolinaire (Journal article; Peer reviewed, 2020)Background Tuberculosis is among the top-10 causes of mortality in children with more than 1 million children suffering from TB disease annually worldwide. The main challenge in young children is the difficulty in ... -
Prevention of Mother-to-Child Transmission of HIV-1 in Lesotho
Tiam, Appolinaire (Doctoral thesis, 2020-12-11)The number of new pediatric HIV-1 infections is reducing globally as services for the prevention of mother-to-child transmission of HIV-1 (PMTCT) are being scaled up. Lesotho has one of the highest HIV burdens globally ...