• Exposure to Air Pollution during Pregnancy and Childhood, and White Matter Microstructure in Preadolescents 

      Lubczyńska, Małgorzata J.; Muetzel, Ryan L.; El Marroun, Hanan; Basagaña, Xavier; Strak, Maciej; Denault, William Robert Paul; Jaddoe, Vincent W.V.; Hillegers, Manon; Vernooij, Meike W.; Hoek, Gerard; White, Tonya; Brunekreef, Bert; Tiemeier, Henning; Guxens, Mònica (Journal article; Peer reviewed, 2020)
      Background: Air pollution has been related to brain structural alterations, but a relationship with white matter microstructure is unclear. Objectives: We assessed whether pregnancy and childhood exposures to air ...
    • Genome-wide association meta-analysis of childhood and adolescent internalizing symptoms 

      Jami, Eshim S.; Hammerschlag, Anke R.; Ip, Hill F.; Allegrini, Andrea G.; Benyamin, Beben; Border, Richard; Diemer, Elizabeth W.; Jiang, Chang; Karhunen, Ville; Lu, Yi; Lu, Qing; Mallard, Travis T.; Mishra, Pashupati P.; Nolte, Ilja M.; Palviainen, Teemu; Peterson, Roseann E.; Sallis, Hannah M.; Shabalin, Andrey A.; Tate, Ashley E.; Thiering, Elisabeth; Vilor-Tejedor, Natàlia; Wang, Carol; Zhou, Ang; Adkins, Daniel E.; Alemany, Silvia; Ask, Helga; Chen, Qi; Corley, Robin P.; Ehli, Erik A.; Evans, Luke M.; Havdahl, Alexandra; Hagenbeek, Fiona A.; Hakulinen, Christian; Henders, Anjali K.; Hottenga, Jouke Jan; Korhonen, Tellervo; Mamun, Abdullah; Marrington, Shelby; Neumann, Alexander; Rimfeld, Kaili; Rivadeneira, Fernando; Silberg, Judy L.; van Beijsterveldt, Catharina E.; Vuoksimaa, Eero; Whipp, Alyce M.; Tong, Xiaoran; Andreassen, Ole; Boomsma, Dorret I.; Brown, Sandra A.; Burt, S. Alexandra; Copeland, William; Dick, Danielle M.; Harden, K. Paige; Harris, Kathleen Mullan; Hartman, Catharina A.; Heinrich, Joachim; Hewitt, John K.; Hopfer, Christian; Hypponen, Elina; Jarvelin, Marjo-Riitta; Kaprio, Jaakko; Keltikangas-Järvinen, Liisa; Klump, Kelly L.; Krauter, Kenneth; Kuja-Halkola, Ralf; Larsson, Henrik; Lehtimäki, Terho; Lichtenstein, Paul; Lundström, Sebastian; Maes, Hermine H.; Magnus, Per Minor; Munafò, Marcus R.; Najman, Jake M.; Njølstad, Pål Rasmus; Oldehinkel, Albertine J.; Pennell, Craig E.; Plomin, Robert; Reichborn-Kjennerud, Ted; Reynolds, Chandra; Rose, Richard J.; Smolen, Andrew; Snieder, Harold; Stallings, Michael; Standl, Marie; Sunyer, Jordi; Tiemeier, Henning; Wadsworth, Sally J.; Wall, Tamara L.; Whitehouse, Andrew J.O.; Williams, Gail M.; Ystrøm, Eivind; Nivard, Michel G.; Bartels, Meike; Middeldorp, Christel M. (Journal article; Peer reviewed, 2022)
      Objective: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. Method: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated ...
    • Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns 

      Joubert, Bonnie R; Den Dekker, Herman T; Felix, Janine F; Bohlin, Jon; Ligthart, Symen; Beckett, Emma; Tiemeier, Henning; van Meurs, Joyce B; Uitterlinden, Andre G; Hofman, Albert; Håberg, Siri Eldevik; Reese, Sarah E; Peters, Marjolein J; Kulle Andreassen, Bettina; Steegers, Eric A P; Nilsen, Roy Miodini; Vollset, Stein Emil; Midttun, Øivind; Ueland, Per Magne; Franco, Oscar H; Dehghan, Abbas; De Jongste, Johan C; Wu, Michael C; Wang, Tianyuan; Peddada, Shyamal D; Jaddoe, Vincent W V; Nystad, Wenche; Duijts, Liesbeth; London, Stephanie J (Peer reviewed; Journal article, 2016-02-10)
      Folate is vital for fetal development. Periconceptional folic acid supplementation and food fortification are recommended to prevent neural tube defects. Mechanisms whereby periconceptional folate influences normal development ...
    • Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease 

      Crawford, Andrew A.; Bankier, Sean; Altmaier, Elisabeth; Barnes, Catriona L. K.; Clark, David W.; Ermel, Raili; Friedrich, Nele; van der Harst, Pim; Joshi, Peter K.; Karhunen, Ville; Lahti, Jari; Mahajan, Anubha; Mangino, Massimo; Nethander, Maria; Neumann, Alexander; Pietzner, Maik; Sukhavasi, Katyayani; Wang, Carol A.; Bakker, Stephan J. L.; Bjorkegren, Johan L. M.; Campbell, Harry; Eriksson, Johan G.; Gieger, Christian; Hayward, Caroline; Jarvelin, Marjo-Riitta; McLachlan, Stela; Morris, Andrew P.; Ohlsson, Claes; Pennell, Craig E.; Price, Jackie; Rudan, Igor; Ruusalepp, Arno; Spector, Tim; Tiemeier, Henning; Völzke, Henry; Wilson, James F.; Michoel, Tom Luk Robert; Timpson, Nicolas J.; Smith, George Davey; Walker, Brian R. (Journal article; Peer reviewed, 2021)
      The stress hormone cortisol modulates fuel metabolism, cardiovascular homoeostasis, mood, inflammation and cognition. The CORtisol NETwork (CORNET) consortium previously identified a single locus associated with morning ...