• Aetiological risk factors are associated with distinct imaging findings in patients with chronic pancreatitis: A study of 959 cases from the Scandinavian Baltic Pancreatic Club (SBPC) imaging database 

      Engjom, Trond; Nordaas, Ingrid Kvåle; Tjora, Erling; Dimcevski, Georg Gjorgji; Haldorsen, Ingfrid S.; Olesen, Søren Schou; Drewes, Asbjørn Mohr; Zviniene, Kristina; Barauskas, Giedrus; Riis Jespersen, Hans Søe; Jensen, Nanna; Borch, Anders; Nøjgaard, Camilla; Novovic, Srdan; Kardasheva, Svetlana S.; Okhlobystin, Alexey; Hauge, Truls; Waage, Anne; Frøkjær, Jens Brøndum (Journal article; Peer reviewed, 2021)
      Objectives The relation between aetiology and structural changes of the pancreas in patients with chronic pancreatitis (CP) is not fully understood. Earlier studies are limited by focusing on selected factors in studies ...
    • Automated spectrophotometric bicarbonate analysis in duodenal juice compared to the back titration method 

      Erchinger, Friedemann Georg; Engjom, Trond; Gudbrandsen, Oddrun Anita; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2016-02-03)
      Objectives We have recently evaluated a short endoscopic secretin test for exocrine pancreatic function. Bicarbonate concentration in duodenal juice is an important parameter in this test. Measurement of bicarbonate by ...
    • Diagnostic accuracy of a short endoscopic secretin test in patients with cystic fibrosis 

      Engjom, Trond; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Tjora, Erling; Aksnes, Lage; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2015-02-16)
      Objective: Short endoscopic secretin tests for exocrine pancreatic function are not properly evaluated in cystic fibrosis (CF). Methods: Patients with CF and healthy controls (HCs) underwent endoscopic collection of duodenal ...
    • Exocrine pancreas insufficiency in chronic pancreatitis – Risk factors and associations with complications. A multicentre study of 1869 patients 

      Erchinger, Friedemann Georg; Engjom, Trond; Dimcevski, Georg Gjorgji; Drewes, Asbjørn M.; Olesen, Søren Schou; Vujasinovic, Miroslav; Löhr, Johannes-Matthias; Nøjgaard, Camilla; Novovic, Srdan; Laukkarinen, Johanna; Parhiala, Mikael; Björn, Lindkvist; Waage, Anne; Hauge, Truls; Pukitis, Aldis; Ozola-Zalite, Imanta; Kalaitzakis, Evangelos; Okhlobystin, Alexey; Barauskas, Giederius; Efsen, Dahl Eva; Tjora, Erling (Journal article; Peer reviewed, 2022)
      Background/objectives There is scarce information about risk factors for exocrine pancreas insufficiency (EPI) in chronic pancreatitis (CP), and how it associates with other complications. The aim of the present study was ...
    • Fecal fat analyses in chronic pancreatitis importance of fat ingestion before stool collection 

      Erchinger, Friedemann Georg; Engjom, Trond; Jurmy, Palwasha; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2017-01-17)
      Objective: Quantitative determination of fecal fat still is the gold standard for measuring malabsorption. We evaluated the importance of standardized food intake before and under the collection of feces. Material and ...
    • Fucosylated AGP glycopeptides as biomarkers of HNF1A-Maturity onset diabetes of the young 

      Tijardović, Marko; Štambuk, Tamara; Juszczak, Agata; Keser, Toma; Gasperikova, Daniela; Novokmet, Mislav; Tjora, Erling; Pape Medvidović, Edita; Stanik, Juraj; Njølstad, Pål Rasmus; Lauc, Gordan; Owen, Katharine R.; Gornik, Olga (Journal article; Peer reviewed, 2022)
      Aims: We previously demonstrated that antennary fucosylated N-glycans on plasma proteins are regulated by HNF1A and can identify cases of Maturity-Onset Diabetes of the Young caused by HNF1A variants (HNF1A-MODY). Based ...
    • KRAS mutation analysis by droplet digital PCR of duodenal juice from patients with MODY8 and other pancreatic diseases 

      Choi, Man Hung; Tjora, Erling; Forthun, Rakel Brendsdal; Engjom, Trond; Ræder, Helge; Hovland, Randi; Molven, Anders (Journal article; Peer reviewed, 2021)
      Background Maturity-onset diabetes of the young type 8 (MODY8 or CEL-MODY) is an inherited pancreatic disease characterized by chronic inflammation of the pancreas and diabetes. It is not known whether MODY8 patients ...
    • Novel endoscopic and MRI-based methods for evaluating exocrine pancreatic function in pancreatitis and monogenic forms of diabetes 

      Tjora, Erling (Doctoral thesis; Peer reviewed, 2013-11-15)
      Background: Monogenic diabetes (Maturity onset diabetes in the young, MODY) are autosomal dominantly inherited diabetes syndromes characterized by diabetes due to beta cell dysfunction, with typical onset of diabetes before ...
    • Pancreatic enzyme treatment in chronic pancreatitis: Quality of management and adherence to guidelines–A cross-sectional observational study 

      Erchinger, Friedemann Georg; Tjora, Erling; Nordaas, Ingrid Kvåle; Dimcevski, Georg Gjorgji; Olesen, Søren Schou; Jensen, Nanna; Dahl, Eva Efsen; Borch, Anders; Nøjgaard, Camilla; Novovic, Srdan; Barauskas, Giedrus; Ignatavicius, Povilas; Vujasinovic, Miroslav; Lőhr, Matthias; Laukkarinen, Johanna; Parhiala, Mikael; Drewes, Asbjørn Mohr; Engjom, Trond (Journal article; Peer reviewed, 2022)
      Objectives Pancreatic exocrine insufficiency (PEI) is a common complication in patients with chronic pancreatitis (CP), leading to increased morbidity and mortality if not treated adequately. Pancreatic enzyme replacement ...
    • Secretin-stimulated ultrasound estimation of pancreatic secretion in cystic fibrosis validated by magnetic resonance imaging 

      Engjom, Trond; Tjora, Erling; Wathle, Gaute Kjellevold; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Gilja, Odd Helge; Haldorsen, Ingfrid S.; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2018-04)
      Objectives: Secretin-stimulated magnetic resonance imaging (s-MRI) is the best validated radiological modality assessing pancreatic secretion. The purpose of this study was to compare volume output measures from ...
    • Structural imaging findings are related to clinical complications in chronic pancreatitis 

      Nordaas, Ingrid Kvåle; Tjora, Erling; Dimcevski, Georg Gjorgji; Haldorsen, Ingfrid S.; Olesen, Søren Schou; Drewes, Asbjørn Mohr; Zviniene, Kristina; Barauskas, Giedrius; Bayram, Berivan Kyed; Nørregaard, Peter; Borch, Anders; Nøjgaard, Camilla; Jensen, Annette Bøjer; Kardasheva, Svetlana S.; Okhlobystin, Alexey; Hauge, Truls; Waage, Anne; Frøkjær, Jens Brøndum; Engjom, Trond (Journal article; Peer reviewed, 2022)
      Background/objectives: Structural pancreatic changes and complications related to chronic pancreatitis are well described, but little is known about their relationship. We aimed to explore the associations between pancreatic ...
    • Two New Mutations in the CEL Gene Causing Diabetes and Hereditary Pancreatitis: How to Correctly Identify MODY8 Cases 

      Jellas, Khadija el; Dušátková, Petra; Haldorsen, Ingfrid S.; Molnes, Janne; Tjora, Erling; Johansson, Bente Berg; Fjeld, Karianne; Johansson, Stefan; Průhová, Štěpánka; Groop, Leif; Löhr, J. Matthias; Njølstad, Pål Rasmus; Molven, Anders (Journal article; Peer reviewed, 2022)
      Context Maturity onset diabetes of the young, type 8 (MODY8) is associated with mutations in the CEL gene, which encodes the digestive enzyme carboxyl ester lipase. Several diabetes cases and families have in recent years ...
    • Ultrasound echo-intensity predicts severe Pancreatic affection in cystic fibrosis patients 

      Engjom, Trond; Erchinger, Friedemann Georg; Lærum, Birger Norderud; Tjora, Erling; Gilja, Odd Helge; Dimcevski, Georg Gjorgji (Peer reviewed; Journal article, 2015-03-24)
      Background: Pancreatic destruction affects the majority of patients with cystic fibrosis. We aimed to relate ultrasound findings to exocrine pancreatic function and cystic fibrosis genotype. Methods: Patients with cystic ...