Blar i Bergen Open Research Archive på forfatter "Totland, Cecilie"

Viser treff 1-6 av 6

    • Altered exosomal miRNA profiles in patients with paraneoplastic cerebellar degeneration 

      Solheim, Eirik Tveit; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Anandan, Shamundeeswari; Peter, Elise; Desestret, Virginie; Totland, Cecilie; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2024)
      Objective Patients with ovarian cancer (OC) may develop anti-Yo-associated paraneoplastic cerebellar degeneration (PCD)—a cerebellar ataxia associated with tumor-induced autoimmunity against CDR2 and CDR2L proteins. ...

    • CDR2 antigen and Yo antibodies 

      Totland, Cecilie; Aarskog, Nina K.; Eichler, Tilo W.; Haugen, Mette; Nøstbakken, Jane K.; Monstad, Sissel E.; Salvesen, Helga Birgitte; Mørk, Sverre; Haukanes, Bjørn Ivar; Vedeler, Christian A. (Peer reviewed; Journal article, 2011)
      Paraneoplastic cerebellar degeneration (PCD) is often associated with Yo antibodies that are directed against human cerebellar degeneration-related protein 2 (CDR2). Such antibodies may also be found in ovarian cancer ...

    • A cerebellar degeneration-related protein 2-like cell-based assay for anti-Yo detection in patients with paraneoplastic cerebellar degeneration 

      Erikstad, Kjell Inge; Herdlevær, Ida Ajvazi; Peter, Elise Marie; Haugen, Mette; Totland, Cecilie; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2023)
      Background and purpose Commercially available tests for Yo antibody detection have low specificity for paraneoplastic cerebellar degeneration (PCD) because these assays use cerebellar degeneration-related protein 2 (CDR2) ...

    • CRMP5 Antibodies—Diagnostic Challenges 

      Totland, Cecilie; Haugen, Mette; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2021-09-22)
      CRMP5-associated paraneoplastic neurological syndromes (PNS) are rare, and only few studies describe larger cohorts of patients with CRMP5 antibodies. We have included 24 patients with CRMP5 antibodies and compared clinical ...

    • Multi-omics profiling reveals dysregulated ribosome biogenesis and impaired cell proliferation following knockout of CDR2L 

      Solheim, Eirik Tveit; Gerking, Yola; Kråkenes, Torbjørn; Herdlevær, Ida; Birkeland, Even; Totland, Cecilie; Dick, Fiona; Vedeler, Christian Alexander (Journal article; Peer reviewed, 2024)
      Background Cerebellar degeneration-related (CDR) proteins are associated with paraneoplastic cerebellar degeneration (PCD) – a rare, neurodegenerative disease caused by tumour-induced autoimmunity against neural antigens ...

    • Onconeural antibodies with special reference to anti-Yo 

      Totland, Cecilie (Doctoral thesis, 2011-12-20)
      The mechanisms behind anti-Yo mediated paraneoplastic cerebellar degeneration is still not understood, and very little is known about the function of CDR2. In our studies we have tried to elucidate the properties of Yo ...