Blar i Bergen Open Research Archive på forfatter "Valeur, Jørgen"
-
Changes in fecal short-chain fatty acids following fecal microbiota transplantation in patients with irritable bowel syndrome
El-Salhy, Magdy; Valeur, Jørgen; Hausken, Trygve; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2020)Background Short‐chain fatty acids (SCFAs) may play a role in the pathophysiology of irritable bowel syndrome (IBS). This study analyzed fecal SCFAs after performing fecal microbiota transplantation (FMT) in the IBS ... -
Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
Mazzawi, Tarek; Hausken, Trygve; Hov, Johannes Espolin Roksund; Valeur, Jørgen; Sangnes, Dag André; El-Salhy, Magdy; Gilja, Odd Helge; Hatlebakk, Jan Gunnar; Lied, Gülen Arslan (Peer reviewed; Journal article, 2019)Objectives: Irritable bowel syndrome (IBS) may be associated with disturbances in gut microbiota composition and functions. We recently performed a study of fecal microbiota transplantation (FMT) in diarrhea-predominant ... -
Duodenal administered seal oil for patients with subjective food hypersensitivity: an explorative open pilot study
Gregersen, Kine; Lind, Ragna Anne; Valeur, Jørgen; Bjørkkjær, Tormod; Berstad, Arnold; Lied, Gülen Arslan (Peer reviewed; Journal article, 2010-12)Short-term duodenal administration of n-3 polyunsaturated fatty acid (PUFA)-rich seal oil may improve gastrointestinal complaints in patients with subjective food hypersensitivity, as well as joint pain in patients with ... -
Effects of a Cod Protein Hydrolysate Supplement on Symptoms, Gut Integrity Markers and Fecal Fermentation in Patients with Irritable Bowel Syndrome
Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Valeur, Jørgen; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (Peer reviewed; Journal article, 2019-07-17)Peptides from fish may beneficially affect several metabolic outcomes, including gut health and inflammation. The effect of fish peptides in subjects with irritable bowel syndrome (IBS) has not previously been investigated, ... -
Fecal bacteria and short-chain fatty acids in irritable bowel syndrome: relations to subtype
Teige, Erica Sande; Hillestad, Eline; Steinsvik, Elisabeth Kjelsvik; Brønstad, Ingeborg; Lundervold, Arvid; Lundervold, Astri J.; Valeur, Jørgen; Hausken, Trygve; Jacobsen, Birgitte Berentsen; Lied, Gülen Arslan (Journal article; Peer reviewed, 2024)Background: The relationship between gut microbiota and irritable bowel syndrome (IBS) subtype is unclear. We aimed to explore whether differences in fecal bacteria composition and short-chain fatty acid (SCFA) levels were ... -
Food allergy alters jejunal circular muscle contractility and induces local inflammatory cytokine expression in a mouse model
Valeur, Jørgen; Lappalainen, Jani; Rita, Hannu; Lin, Aung Htun; Kovanen, Petri T.; Berstad, Arnold; Eklund, Kari K.; Vaali, Kirsi Kaarina (Peer reviewed; Journal article, 2009-05-18)Background: We hypothesized that food allergy causes a state of non-specific jejunal dysmotility. This was tested in a mouse model. Methods: Balb/c mice were epicutaneously sensitized with ovalbumin and challenged with 10 ... -
Impact of HIV and type 2 diabetes on gut microbiota diversity, tryptophan catabolism and endothelial dysfunction
Hoel, Hedda Benedicte; Hove-Skovsgaard, Malene; Hov, Johannes Espolin Roksund; Gaardbo, Julie Christine; Holm, Kristian; Kummen, Martin; Rudi, Knut; Nwosu, Felix; Valeur, Jørgen; Gelpi, Marco; Seljeflot, Ingebjørg; Ueland, Per Magne; Gerstoft, Jan; Ullum, Henrik; Aukrust, Pål; Nielsen, Susanne Dam; Trøseid, Marius (Peer reviewed; Journal article, 2018-04-30)HIV infection and type 2 diabetes are associated with altered gut microbiota, chronic inflammation, and increased cardiovascular risk. We aimed to investigate the combined effect of these diseases on gut microbiota composition ... -
Intestinal fermentation in patients with self-reported food hypersensitivity: painful, but protective?
Valeur, Jørgen; Morken, Mette Helvik; Norin, Elisabeth; Midtvedt, Tore; Berstad, Arnold (Peer reviewed; Journal article, 2010-07-03)Purpose: Enterometabolic disturbances may cause meal-related symptoms. We performed a functional evaluation of the intestinal microflora in patients with unexplained, self-reported food hypersensitivity by measuring fecal ... -
Long-term effects of fecal microbiota transplantation (FMT) in patients with irritable bowel syndrome
El-Salhy, Magdy; Bråthen Kristoffersen, Anja; Valeur, Jørgen; Casén, Christina; Hatlebakk, Jan Gunnar; Gilja, Odd Helge; Hausken, Trygve (Journal article; Peer reviewed, 2021)Background We recently found fecal microbiota transplantation (FMT) in irritable bowel syndrome (IBS) patients to be an effective and safe treatment after 3 months. The present follow-up study investigated the efficacy ... -
Postprandial Symptoms in Patients With Functional Dyspepsia and Irritable Bowel Syndrome: Relations to Ultrasound Measurements and Psychological Factors
Steinsvik, Elisabeth Kjelsvik; Valeur, Jørgen; Hausken, Trygve; Gilja, Odd Helge (Journal article; Peer reviewed, 2020)Background/Aims Dyspeptic symptoms are common in patients with functional gastrointestinal (GI) disorders, and may be related to visceral hypersensitivity. We aim to explore the relation between visceral hypersensitivity ... -
Responses to faecal microbiota transplantation in female and male patients with irritable bowel syndrome
El-Salhy, Magdy; Casén, Christina; Valeur, Jørgen; Hausken, Trygve; Hatlebakk, Jan Gunnar (Journal article; Peer reviewed, 2021-05-14)BACKGROUND Faecal microbiota transplantation (FMT) seems to be a promising treatment for irritable bowel syndrome (IBS) patients. In Western countries (United States and Europe), there is a female predominance in IBS. A ... -
Study protocol of the Bergen brain-gut-microbiota-axis study: A prospective case-report characterization and dietary intervention study to evaluate the effects of microbiota alterations on cognition and anatomical and functional brain connectivity in patients with irritable bowel syndrome
Berentsen, Birgitte; Nagaraja, Bharath Halandur; Teige, Erica Persson; Lied, Gülen Arslan; Lundervold, Astri; Lundervold, Katarina; Steinsvik, Elisabeth Kjelsvik; Hillestad, Eline Margrete Randulff; Valeur, Jørgen; Brønstad, Ingeborg; Gilja, Odd Helge; Osnes, Berge; Hatlebakk, Jan Gunnar; Haász, Judit; Labus, Jennifer; Gupta, Arpana; Mayer, Emeran; Benitez-Páez, Alfonso; Sanz, Yolanda; Lundervold, Arvid; Hausken, Trygve (Journal article; Peer reviewed, 2020-09)Introduction: Irritable bowel syndrome (IBS) is a common clinical label for medically unexplained gastrointestinal (GI) symptoms, recently described as a disturbance of the brain-gut-microbiota (BGM) axis. To gain a ... -
Subjective food hypersensitivity: assessment of enterochromaffin cell markers in blood and gut lavage fluid
Gregersen, Kine; Valeur, Jørgen; Lillestøl, Kristine; Frøyland, Livar; Araujo, Pedro; Lied, Gülen Arslan; Berstad, Arnold (Peer reviewed; Journal article, 2011-08)Background: Food hypersensitivity is commonly suspected, but seldom verified. Patients with subjective food hypersensitivity suffer from both intestinal and extraintestinal health complaints. Abnormalities of the ... -
Unexplained, self-reported food hypersensitivity. Explorative studies on mechanisms of abdominal symptom generation
Valeur, Jørgen (Doctoral thesis, 2010-10-08)Background: Self-reported food hypersensitivity remains unexplained in most cases. Abdominal symptoms, typically consistent with the irritable bowel syndrome (IBS), are common in patients with such unexplained, self-reported ...