Browsing Bergen Open Research Archive by Author "Van de Perre, Philippe"
Now showing items 1-11 of 11
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Eliminating HIV transmission through breast milk from women taking antiretroviral drugs
Goga, Ameena; Van de Perre, Philippe; Ngandu, Nobubelo; Nagot, Nicolas; Abrams, Elaine J; Moodley, Dhayendre; King, Rachel; Molès, Jean-Pierre; Chirinda, Witness; Scarlatti, Gabriella; Tylleskär, Thorkild; Sherman, Gayle G; Pillay, Yogan; Dabis, François; Gray, Glenda (Journal article; Peer reviewed, 2021) -
Eliminating postnatal HIV transmission in high incidence areas: need for complementary biomedical interventions
Van de Perre, Philippe; Goga, Ameena; Ngandu, Nobubelo; Nagot, Nicolas; Moodley, Dhayendre; King, Rachel; Molès, Jean-Pierre; Mosqueira, Beatriz; Chirinda, Witness; Scarlatti, Gabriella; Tylleskär, Thorkild; Dabis, François; Gray, Glenda (Journal article; Peer reviewed, 2021)The rate of mother-to-child transmission (MTCT) of HIV from breastfeeding is increasing relative to other causes of MTCT. Early effective preconception and antenatal antiretroviral therapy (ART) reduces intrauterine and ... -
Growth effects of exclusive breastfeeding promotion by peer counsellors in sub-Saharan Africa: the cluster-randomised PROMISE EBF trial
Engebretsen, Ingunn Marie S.; Jackson, Debra; Fadnes, Lars Thore; Nankabirwa, Victoria; Diallo, Abdoulaye Hama; Doherty, Tanya Mark; Lombard, Carl; Swanevelder, Sonja; Nankunda, Jolly; Ramokolo, Vundli; Sanders, David; Wamani, Henry; Meda, Nicolas; Tumwine, James K.; Ekström, Eva-Charlotte; Van de Perre, Philippe; Kankasa, Chipepo; Sommerfelt, Halvor; Tylleskär, Thorkild; on behalf of the PROMISE EBF-study group (Peer reviewed; Journal article, 2014-06-21)Background: In this multi-country cluster-randomized behavioural intervention trial promoting exclusive breastfeeding (EBF) in Africa, we compared growth of infants up to 6 months of age living in communities where peer ... -
Growth, clinical and neurodevelopmental outcomes at school age are similar for children who received 1‑year lamivudine or lopinavir/ritonavir HIV prophylaxis in early life
Nagot, Nicolas; Singata-Madliki, Mandisa; Cournil, Amandine; Nalugya, Joyce; Tassembedo, Soleymane; Quillet, Catherine; Tonga, Melany W.; Tumwine, James K; Meda, Nicolas; Kankasa, Chipepo; Mwiya, Mwiya; Bangirana, Paul; Peries, Marianne; Batting, Joanne; Engebretsen, Ingunn Marie Stadskleiv; Tylleskär, Thorkild; Van de Perre, Philippe; Ndeezi, Grace; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)In the ANRS 12174 trial, HIV-exposed uninfected African neonates who received lopinavir-ritonavir (LPV/r) prophylaxis for 1 year exhibited slower growth from birth to week 50 compared with those receiving lamivudine (3TC). ... -
HIV viral load non-suppression and associated factors among pregnant and postpartum women in rural northeastern South Africa: a cross-sectional survey
Ngandu, Nobubelo Kwanele; Lombard, Carl; Mbira, Thandiwe Elsie; Puren, Adrian; Waitt, Catriona; Prendergast, Andrew J.; Tylleskär, Thorkild; Van de Perre, Philippe; Goga, Ameena (Journal article; Peer reviewed, 2022)Objectives We aimed to measure the prevalence of maternal HIV viral load (VL) non-suppression and assess associated factors, to evaluate progress towards United Nations-AIDS (UNAIDS) targets. Design Cross-sectional ... -
Increased Epstein-Barr virus in breast milk occurs with subclinical mastitis and HIV shedding
Sanosyan, Armen; Rutagwera, David Gatsinzi; Moles, Jean-Pierre; Bollore, Karine; Peries, Marianne; Kankasa, Chipepo; Mwiya, Mwiya; Tylleskär, Thorkild; Nagot, Nicolas; Van de Perre, Philippe; Tuaillon, Edouard (Peer reviewed; Journal article, 2016-07)Epstein–Barr virus (EBV) in breast milk and subclinical mastitis (SCM) are both associated with human immunodeficiency virus (HIV) shedding and possibly with postnatal HIV transmission. The objective of this nested ... -
Long-term persistence of mitochondrial DNA instability in HIV-exposed uninfected children during and after exposure to antiretroviral drugs and HIV
Desquiret-Dumas, Valérie; D’Ottavi, Morgana; Monnin, Audrey; Goudenège, David; Méda, Nicolas; Vizeneux, Amélie; Kankasa, Chipepo; Tylleskär, Thorkild; Bris, Céline; Procaccio, Vincent; Nagot, Nicolas; Van de Perre, Philippe; Reynier, Pascal; Molès, Jean-Pierre (Journal article; Peer reviewed, 2022)HIV-exposed uninfected (HEU) children show impaired health outcomes during childhood. A high rate of mitochondrial DNA (mtDNA) instability was reported in the blood of HEU at birth. We aimed to explore the relationship ... -
Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis
Monnin, Audrey; Vizeneux, Amélie; Nagot, Nicolas; Eymard-Duvernay, Sabrina; Meda, Nicolas; Singata-Madliki, Mandisa; Ndeezi, Grace; Tumwine, James K; Kankasa, Chipepo; Goga, Ameena; Tylleskär, Thorkild; Van de Perre, Philippe; Molès, Jean-Pierre (Journal article; Peer reviewed, 2021)Telomere shortening can be enhanced upon human immunodeficiency virus (HIV) infection and by antiretroviral (ARV) exposures. The aim of this study was to evaluate the acute and long-term effect on telomere shortening of ... -
Lopinavir/Ritonavir versus Lamivudine peri-exposure prophylaxis to prevent HIV-1 transmission by breastfeeding: the PROMISE-PEP trial Protocol ANRS 12174
Nagot, Nicolas; Kankasa, Chipepo; Meda, Nicolas; Hofmeyr, Justus; Nikodem, Cheryl; Tylleskär, Thorkild; Tumwine, James K.; Karamagi, Charles; Sommerfeldt, Halvor; Neveu, Dorine; Van de Perre, Philippe; for the PROMISE-PEP group (Peer reviewed; Journal article, 2012-10-06)Background: Postnatal transmission of HIV-1 through breast milk remains an unsolved challenge in many resource-poor settings where replacement feeding is not a safe alternative. WHO now recommends breastfeeding of infants ... -
Prevalence and determinants of HIV shedding in breast milk during continued breastfeeding among Zambian mothers not on antiretroviral treatment (ART): A cross-sectional study
Rutagwera, David Gatsinzi; Molès, Jean-Pierre; Kankasa, Chipepo; Mwiya, Mwiya; Tuaillon, Edouard; Peries, Marianne; Nagot, Nicolas; Van de Perre, Philippe; Tylleskär, Thorkild (Peer reviewed; Journal article, 2019)The risk of postnatal HIV transmission exists throughout the breastfeeding period. HIV shedding in breast milk beyond six months has not been studied extensively. The aim of this study was to determine prevalence and ... -
Recurrent Severe Subclinical Mastitis and the Risk of HIV Transmission Through Breastfeeding
Rutagwera, David Gatsinzi; Molès, Jean-Pierre; Kankasa, Chipepo; Mwiya, Mwiya; Tuaillon, Edouard; Peries, Marianne; Nagot, Nicolas; Van de Perre, Philippe; Tylleskär, Thorkild (Journal article; Peer reviewed, 2022)Subclinical mastitis (SCM) is an important risk factor of postnatal HIV-1 transmission that is still poorly understood. A longitudinal sub-study of the ANRS12174 trial including 270 breastfeeding mothers in Lusaka, Zambia ...