• Cancer risk in children of mothers with epilepsy and high-dose folic acid use during pregnancy 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Alvestad, Silje; Gilhus, Nils Erik; Gissler, Mika; Igland, Jannicke; Leinonen, Maarit; Tomson, Torbjörn; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2022)
      Importance: Women with epilepsy are recommended high doses of folic acid before and during pregnancy owing to risk of congenital anomalies associated with antiseizure medications. Whether prenatal exposure to high-dose ...
    • High-Dose Folic Acid Use during Pregnancy and Cancer Risk in Mothers and Children With Focus on Maternal Epilepsy 

      Vegrim, Håkon Magne (Doctoral thesis, 2024-05-23)
      Norsk sammendrag: Bakgrunn: Gravide kvinner som tar antianfallsmedikasjon (ASM) anbefales høyere daglige doser av folsyre (>1 mg) enn den generelle befolkningen (0.4–0.8 mg) for å beskytte fosteret. Folsyre, den syntetiske ...
    • Pregnancy, folic acid, and antiseizure medication 

      Bjørk, Marte-Helene; Vegrim, Håkon Magne; Alvestad, Silje; Monsen, Anne-Lise Bjørke; Riedel, Bettina Maria Ingeborg; Gilhus, Nils Erik; Husebye, Elisabeth Synnøve Nilsen (Journal article; Peer reviewed, 2023)
      Background Although some antiseizure medications (ASMs) are teratogenic, most people with epilepsy need treatment in pregnancy. The risk of ASM fetotoxicity may be mitigated with folic acid. High-dose folic acid ...
    • Prescribing patterns for higher dose folic acid in pregnant women with epilepsy treated with antiseizure medication 

      Vegrim, Håkon Magne; Dreier, Julie Werenberg; Igland, Jannicke; Gilhus, Nils Erik; Alvestad, Silje; Gissler, Mika; Leinonen, Maarit; Sun, Yuelian; Zoega, Helga; Christensen, Jakob; Bjørk, Marte-Helene; Tomson, Torbjörn (Journal article; Peer reviewed, 2024)
      Objective: This study was undertaken to characterize the use of higher doses of folic acid (≥1 mg daily) in relation to pregnancy in Denmark, Norway, and Sweden in women with epilepsy treated with antiseizure medication ...
    • Socioeconomic differences in use of antiseizure medication in pregnancies with maternal epilepsy: A population-based study from Nordic universal health care systems 

      Leinonen, Maarit K.; Igland, Jannicke; Dreier, Julie Werenberg; Alvestad, Silje; Cohen, Jacqueline Mallory; Gilhus, Nils Erik; Gissler, Mika; Sun, Yuelian; Tomson, Torbjörn; Zoega, Helga; Vegrim, Håkon Magne; Christensen, Jakob; Bjørk, Marte-Helene (Journal article; Peer reviewed, 2024)
      Objective Research points to disparities in disease burden and access to medical care in epilepsy. We studied the association between socioeconomic status (SES) and antiseizure medication (ASM) use in pregnancies with ...