Browsing Bergen Open Research Archive by Author "Vik, Alexandra"
Now showing items 1-7 of 7
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Cognitive and MRI trajectories for prediction of Alzheimer’s disease
Abolpour Mofrad, Samaneh; Lundervold, Astri Johansen; Vik, Alexandra; Lundervold, Alexander Selvikvåg (Journal article; Peer reviewed, 2021)The concept of Mild Cognitive Impairment (MCI) is used to describe the early stages of Alzheimer’s disease (AD), and identification and treatment before further decline is an important clinical task. We selected longitudinal ... -
Fractional anisotropy shows differential reduction in frontal-subcortical fiber bundles - A longitudinal MRI study of 76 middle-aged and older adults
Vik, Alexandra; Hodneland, Erlend; Haász, Judit; Ystad, Martin Andreas; Lundervold, Astri; Lundervold, Arvid (Peer reviewed; Journal article, 2015-05-15)Motivated by the frontal- and white matter (WM) retrogenesis hypotheses and the assumptions that fronto-striatal circuits are especially vulnerable in normal aging, the goal of the present study was to identify fiber bundles ... -
Functional activity level reported by an informant is an early predictor of Alzheimer’s disease
Vik, Alexandra; Kocinski, Marek Michal; Rye, Ingrid Karlsen; Lundervold, Astri J.; Lundervold, Alexander Selvikvåg (Journal article; Peer reviewed, 2023)Background Loss of autonomy in day-to-day functioning is one of the feared outcomes of Alzheimer’s disease (AD), and relatives may have been worried by subtle behavioral changes in ordinary life situations long before these ... -
Lateral ventricle volume trajectories predict response inhibition in older age-A longitudinal brain imaging and machine learning approach.
Lundervold, Astri; Vik, Alexandra; Lundervold, Arvid (Peer reviewed; Journal article, 2019-04-02)Objective In a three-wave 6 yrs longitudinal study we investigated if the expansion of lateral ventricle (LV) volumes (regarded as a proxy for brain tissue loss) predicts third wave performance on a test of response ... -
Longitudinal stability of the brain functional connectome is associated with episodic memory performance in aging
Ousdal, Olga Therese; Kaufmann, Tobias; Kolskår, Knut-Kristian; Vik, Alexandra; Wehling, Eike; Lundervold, Astri; Lundervold, Arvid; Westlye, Lars Tjelta (Peer reviewed; Journal article, 2020)The brain functional connectome forms a relatively stable and idiosyncratic backbone that can be used for identification or “fingerprinting” of individuals with a high level of accuracy. While previous cross‐sectional ... -
Nondirective meditation activates brain areas associated with retrieval of memories and emotional processing
Xu, Jian; Vik, Alexandra; Groote, Inge Rasmus; Lagopoulos, Jim; Holen, Are; Ellingsen, Øyvind; Håberg, Asta; Davanger, Svend (Peer reviewed; Journal article, 2014-02-26)Nondirective meditation techniques are practiced with a relaxed focus of attention that permits spontaneously occurring thoughts, images, sensations, memories, and emotions to emerge and pass freely, without any expectation ... -
Predicting conversion to Alzheimer’s disease in individuals with Mild Cognitive Impairment using clinically transferable features
Rye, Ingrid; Vik, Alexandra; Kocinski, Marek Michal; Lundervold, Alexander Selvikvåg; Lundervold, Astri J. (Journal article; Peer reviewed, 2022)Patients with Mild Cognitive Impairment (MCI) have an increased risk of Alzheimer’s disease (AD). Early identification of underlying neurodegenerative processes is essential to provide treatment before the disease is well ...