• Assessment of Small Bowel Motility and SMA Blood Flow Studied with Transabdominal Ultrasound 

      Nylund, Kim; Gjengsto, Andreas Jessen; Volkmann, Hilde Løland Von; Gilja, Odd Helge (Journal article; Peer reviewed, 2022)
      Purpose: Gastrointestinal ultrasound (GIUS) is a noninvasive imaging technique that may be used to study physiological changes in the small bowel. The aim of the study was to investigate the feasibility of measuring blood ...
    • Comparison of pre-analytical conditions for quantification of serotonin in platelet-poor plasma 

      Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Fiskerstrand, Torunn; Gudbrandsen, Oddrun Anita (Peer reviewed; Journal article, 2019)
      Background: Reported concentrations of serotonin in platelet-poor plasma (PPP) in healthy subjects vary widely due to different pre-analytical procedures. Aim: To examine how different pre-analytical conditions affect the ...
    • Gastrointestinal transit and contractility in diabetic constipation: A wireless motility capsule study on diabetes patients and healthy controls 

      Sangnes, Dag A.; Lundervold, Katarina; Bekkelund, Mattis; Volkmann, Hilde Løland Von; Berentsen, Birgitte; Gilja, Odd Helge; Dimcevski, Georg; Søfteland, Eirik (Journal article; Peer reviewed, 2021)
      Background: Diabetic constipation is traditionally attributed to slow colonic transit, despite limited evidence. More than half of patients find treatment unsatisfactory. To improve treatment, there is a need for better ...
    • Plasma levels of guanylins are reduced in patients with Crohn’s disease 

      Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Tronstad, Rune Rose; Dizdar, Vernesa; Nylund, Kim; Hanevik, Kurt; Hausken, Trygve; Gilja, Odd Helge; Fiskerstrand, Torunn (Journal article; Peer reviewed, 2020)
      Background: Guanylin (GN) and uroguanylin (UGN) are endogenous ligands for the intestinal receptor guanylate cyclase C (GC-C), an important regulator of intestinal fluid homeostasis. Gene expression and protein levels of ...
    • Prolonged intestinal transit and diarrhea in patients with an activating GUCY2C mutation 

      Volkmann, Hilde Løland Von; Brønstad, Ingeborg; Gilja, Odd Helge; Tronstad, Rune Rose; Sangnes, Dag André; Nortvedt, Ragnar; Hausken, Trygve; Dimcevski, Georg Gjorgji; Fiskerstrand, Torunn; Nylund, Kim (Peer reviewed; Journal article, 2017)
      Introduction: Increased intestinal hydration by activation of the epithelial enzyme linked receptor guanylate cyclase C (GC-C) is a pharmacological principle for treating constipation. Activating mutations in the GUCY2C ...
    • Reduced Plasma Guanylin Levels Following Enterotoxigenic Escherichia coli-Induced Diarrhea 

      Brønstad, Ingeborg; Volkmann, Hilde Løland Von; Sakkestad, Sunniva Todnem; Steinsland, Hans; Hanevik, Kurt (Journal article; Peer reviewed, 2023)
      The intestinal peptide hormones guanylin (GN) and uroguanylin (UGN) interact with the epithelial cell receptor guanylate cyclase C to regulate fluid homeostasis. Some enterotoxigenic Escherichia coli (ETEC) produce heat-stable ...