• Breathing patterns in people with exercise-induced laryngeal obstruction 

      Lie, Astrid Haugen; Grønnevik, Ingvild; Frisk, Bente; Røksund, Ola Drange; Hammer, Ida; Vollsæter, Maria; Halvorsen, Thomas; Clemm, Hege Synnøve Havstad (Journal article; Peer reviewed, 2021)
      Exercise-induced laryngeal obstruction (EILO) is common, but we lack readily available diagnostic tools. The larynx represents an important point of resistance in the airways, and we therefore hypothesized that EILO is ...
    • Bronchial hyper-responsiveness after preterm birth 

      Clemm, Hege Synnøve Havstad; Engeseth, Merete Salveson; Vollsæter, Maria; Kotecha, Sailesh; Halvorsen, Thomas (Peer reviewed; Journal article, 2018-03)
      Being born preterm often adversely affects later lung function. Airway obstruction and bronchial hyperresponsiveness (BHR) are common findings. Respiratory symptoms in asthma and in lung disease after preterm birth might ...
    • Children born preterm at the turn of the millennium had better lung function than children born similarly preterm in the early 1990s. 

      Vollsæter, Maria; Skromme, Kaia; Satrell, Emma; Clemm, Hege; Røksund, Ola; Øymar, Knut; Markestad, Trond; Halvorsen, Thomas (Peer reviewed; Journal article, 2015-12-07)
      Objective. Compare respiratory health in children born extremely preterm (EP) or with extremely low birthweight (ELBW) nearly one decade apart, hypothesizing that better perinatal management has led to better outcome. ...
    • Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction 

      Sandnes, Astrid; Andersen, Tiina Maarit; Clemm, Hege Synnøve Havstad; Hilland, Magnus; Heimdal, John-Helge; Halvorsen, Thomas; Røksund, Ola Drange; Vollsæter, Maria (Journal article; Peer reviewed, 2021)
      Purpose Exercise-induced laryngeal obstruction (EILO) is relatively common in young people. Treatment rests on poor evidence; however, inspiratory muscle training (IMT) has been proposed a promising strategy. We aimed to ...
    • Comparison of physical activity and body composition in a cohort of children born extremely preterm or with extremely low birth weight to matched term-born controls: a follow-up study 

      Engan, Mette; Vollsæter, Maria; Øymar, Knut; Markestad, Trond; Eide, Geir Egil; Halvorsen, Thomas; Juliusson, Petur Benedikt; Clemm, Hege Synnøve Havstad (Peer reviewed; Journal article, 2019)
      Objectives: To compare physical activity and body composition in a cohort of children born extremely preterm/extremely low birth weight (EP/ELBW) with term-born (TB) controls. Methods: A regional cohort of children ...
    • Conundrums in the breathless athlete; exercise-induced laryngeal obstruction or asthma? 

      Jansrud, Ida; Halvorsen, Thomas; Vollsæter, Maria; Hilland, Magnus; Heimdal, John-Helge; Røksund, Ola Drange; Clemm, Hege Synnøve Havstad (Journal article; Peer reviewed, 2022)
      Purpose: Exercise-induced bronchoconstriction (EIB) and exercise-induced laryngeal obstruction (EILO) are the two disorders commonly considered when athletes complain of exertional dyspnea. They are highly different but ...
    • Development of health-related quality of life and subjective health complaints in adults born extremely preterm: a longitudinal cohort study 

      Benestad, Merete; Drageset, Jorunn; Eide, Geir Egil; Vollsæter, Maria; Halvorsen, Thomas; Vederhus, Bente Johanne (Journal article; Peer reviewed, 2022)
      Purpose To study development trajectories to 34 years of age of health-related quality of life (HRQoL) and subjective health complaints in extremely preterm (EP) born subjects with and without disability, and to compare ...
    • Development of lung diffusion to adulthood following extremely preterm birth 

      Satrell, Emma Elsa Carolina; Clemm, Hege Synnøve Havstad; Røksund, Ola Drange; Hufthammer, Karl Ove; Thorsen, Einar; Halvorsen, Thomas; Vollsæter, Maria (Journal article; Peer reviewed, 2022)
      Background: Gas exchange in extremely preterm (EP) infants must take place in fetal lungs. Childhood lung diffusing capacity of the lung for carbon monoxide (DLCO) is reduced; however, longitudinal development has not been ...
    • Early life growth and associations with lung function and bronchial hyperresponsiveness at 11-years of age 

      Mikalsen, Ingvild Bruun; Halvorsen, Thomas; Juliusson, Pétur Benedikt; Magnus, Maria Christine; Nystad, Wenche; Stensrud, Trine; Størdal, Ketil; Vollsæter, Maria; Øymar, Knut Asbjørn Alexander (Journal article; Peer reviewed, 2021)
      Low birthweight and being born small-for-gestational age (SGA) are linked to asthma and impaired lung function. Particularly, poor intrauterine growth followed by rapid catch-up growth during childhood may predispose for ...
    • Exercise induced laryngeal obstructions in humans and equines. A comparative review 

      Fretheim-Kelly, Zoe Louise; Halvorsen, Thomas; Clemm, Hege Synnøve Havstad; Roksund, Ola Drange; Heimdal, John-Helge; Vollsæter, Maria; Fintl, Constanze; Strand, Eric (Peer reviewed; Journal article, 2019-10-30)
      Dynamic obstructions of the larynx are a set of disorders that occur during exercise in equines and humans. There are a number of similarities in presentation, diagnosis, pathophysiology and treatment. Both equines and ...
    • Exercise inducible laryngeal obstruction: diagnostics and management 

      Røksund, Ola Drange; Heimdal, John-Helge; Clemm, Hege Synnøve Havstad; Vollsæter, Maria; Halvorsen, Thomas (Peer reviewed; Journal article, 2017-01)
      Obstruction of the central airways is an important cause of exercise-induced inspiratory symptoms (EIIS) in young and otherwise healthy individuals. This is a large, heterogeneous and vastly understudied group of patients. ...
    • Exercise related respiratory problems in the young—Is it exercise-induced bronchoconstriction or laryngeal obstruction? 

      Vollsæter, Maria; Stensrud, Trine; Maat, Robert; Halvorsen, Thomas; Røksund, Ola Drange; Sandnes, Astrid; Clemm, Hege Synnøve Havstad (Journal article; Peer reviewed, 2022)
      Complaints of breathlessness during heavy exercise is common in children and adolescents, and represent expressions of a subjective feeling that may be difficult to verify and to link with specific diagnoses through objective ...
    • Exercise Training in Duchenne Muscular Dystrophy: A Systematic Review and Meta-Analysis 

      Hammer, Stian; Toussaint, Michel; Vollsæter, Maria; Tvedt, Marianne Nesbjørg; Røksund, Ola Drange; Reychler, Gregory; Lund, Hans; Andersen, Tiina Maarit (Journal article; Peer reviewed, 2022)
      Objective: To evaluate the effects and safety of exercise training, and to determine the most effective exercise intervention for people with Duchenne muscular dystrophy. Exercise training was compared with no training, ...
    • Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training 

      Sandnes, Astrid; Andersen, Tiina Maarit; Clemm, Hege Synnøve Havstad; Hilland, Magnus; Vollsæter, Maria; Heimdal, John-Helge; Eide, Geir Egil; Halvorsen, Thomas; Røksund, Ola Drange (Peer reviewed; Journal article, 2019-01-18)
      Background Exercise-induced laryngeal obstruction (EILO) is common in athletes and presents with dyspnoea, chest tightness, inspiratory stridor and sometimes panic reactions. The evidence for conservative treatment is weak, ...
    • Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial 

      Clemm, Hege Synnøve Havstad; Røksund, Ola Drange; Andersen, Tiina Maarit; Heimdal, John-Helge; Karlsen, Tom; Hilland, Magnus; Fretheim-Kelly, Zoe; Hufthammer, Karl Ove; Sandnes, Astrid; Hjelle, Sigrun Margrethe; Vollsæter, Maria; Halvorsen, Thomas (Journal article; Peer reviewed, 2022)
      Background: Exercise-induced laryngeal obstruction (EILO) is a common cause of exertional breathing problems in young individuals, caused by paradoxical inspiratory adduction of laryngeal structures, and diagnosed by ...
    • Expiratory airflow limitation in adults born extremely preterm: A systematic review and meta-analysis 

      Lillebøe, Henriette Lahn-Johannessen; Engeseth, Merete Salveson; Clemm, Hege Synnøve Havstad; Halvorsen, Thomas; Røksund, Ola Drange; Potrebny, Thomas; Vollsæter, Maria (Journal article; Peer reviewed, 2024)
      Extreme preterm (EP) birth, denoting delivery before the onset of the third trimester, interrupts intrauterine development and causes significant early-life pulmonary trauma, thereby posing a lifelong risk to respiratory ...
    • Feasibility and tolerability of measuring translaryngeal pressure during exercise 

      Kelly, Zoe Louise; Halvorsen, Thomas; Heimdal, John-Helge; Strand, Eric; Vollsæter, Maria; Clemm, Hege Synnøve Havstad; Røksund, Ola Drange (Peer reviewed; Journal article, 2019)
      Objectives/Hypothesis: To determine if simultaneous tracheal and supraglottic pressure measurement performed during a continuous laryngoscopy exercise (CLE) test is possible, tolerable, and feasible, and if so, whether ...
    • Health-related quality of life in two birth cohorts of extremely preterm born adults 

      Benestad, Merete; Drageset, Jorunn; Vollsæter, Maria; Hufthammer, Karl Ove; Halvorsen, Thomas; Vederhus, Bente Johanne (Journal article; Peer reviewed, 2024)
      Aim Investigate potential long-term cohort influences on health-related quality of life (HRQoL) in adults born extremely preterm (EP) during the 1980–90s, in view of advancements in neonatal care within that timeframe. ...
    • Impaired Lung Function in Extremely Preterm-Born Adults in Their Fourth Decade of Life 

      Bårdsen, Tonje; Røksund, Ola Drange; Eagan, Tomas Mikal Lind; Hufthammer, Karl Ove; Benestad, Merete Røineland; Clemm, Hege Synnøve Havstad; Halvorsen, Thomas; Vollsæter, Maria (Journal article; Peer reviewed, 2023)
    • Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis 

      Andersen, Tiina Maarit; Sandnes, Astrid; Brekka, Anne Kristine; Hilland, Magnus; Clemm, Hege; Fondenes, Ove; Tysnes, Ole Bjørn; Heimdal, John-Helge; Halvorsen, Thomas; Vollsæter, Maria; Røksund, Ola Drange (Peer reviewed; Journal article, 2017)
      Background: Most patients with amyotrophic lateral sclerosis (ALS) are treated with mechanical insufflation–exsufflation (MI-E) in order to improve cough. This method often fails in ALS with bulbar involvement, allegedly ...