Blar i Bergen Open Research Archive på forfatter "Widlak, Piotr"
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Cross talk between cytokine and hyperthermia-induced pathways: identification of different subsets of NF-κB-dependent genes regulated by TNFα and heat shock
Janus, Patryk; Stokowy, Tomasz; Jaksik, Roman; Szoltysek, Katarzyna; Handschuh, Luiza; Podkowinski, Jan; Widlak, Wieslawa; Kimmel, Marek; Widlak, Piotr (Peer reviewed; Journal article, 2015-05-06)Heat shock inhibits NF-κB signaling, yet the knowledge about its influence on the regulation of NF-κB-dependent genes is limited. Using genomic approaches, i.e., expression microarrays and ChIP-Seq, we aimed to establish ... -
Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes
Korfanty, Joanna; Stokowy, Tomasz; Widlak, Piotr; Gogler-Piglowska, Agnieszka; Handschuh, Luiza; Podkowinski, Jan; Vydra, Natalia; Naumowicz, Anna; Toma-Jonik, Agnieszka; Widlak, Wieslawa (Peer reviewed; Journal article, 2014-12)Heat Shock Factor 1 (HSF1) is the primary transcription factor responsible for the response to cellularstress, while HSF2 becomes activated during development and differentiation, including spermatogen-esis. Although both ... -
The role of NF-κB transcription factor in cellular response to ionizing radiation
Janus, Patryk; Szoltysek, Katarzyna; Zajac, Gracjana; Widlak, Wieslawa; Stokowy, Tomasz; Wojtas, Bartosz; Widlak, Piotr (Journal article, 2019)The NF-κB transcription factor is involved in different aspects of the cellular response to stress, including atypical NF-κB pathway activated by damage induced by ionizing radiation. Moreover, NF-κB could be involved in ...