Blar i Bergen Open Research Archive på forfatter "Wiker, Harald Gotten"
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Consistent biofilm formation by Streptococcus pyogenes emm 1 isolated from patients with necrotizing soft tissue infections
Skutlaberg, Dag Harald; Wiker, Harald Gotten; Mylvaganam, Haima; Norrby-Teglund, Anna; Skrede, Steinar (Journal article; Peer reviewed, 2022-02-18)Objectives: Biofilm formation has been demonstrated in muscle and soft tissue samples from patients with necrotizing soft tissue infection (NSTI) caused by Streptococcus pyogenes, but the clinical importance of this ... -
Immunochemistry-Based Diagnosis of Extrapulmonary Tuberculosis: A Strategy for Large-Scale Production of MPT64-Antibodies for Use in the MPT64 Antigen Detection Test
Hoel, Ida Marie; Ali, Iman A Mohammed; Ishtiaq, Sheeba; Sviland, Lisbet; Wiker, Harald Gotten; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)Tuberculosis (TB) is a global health problem. The immunohistochemistry (IHC)-based MPT64 antigen detection test has shown promising results for diagnosing extrapulmonary TB in previous studies. However, the anti-MPT64 ... -
Label-free quantitative proteomic analysis of the oral bacteria Fusobacterium nucleatum and Porphyromonas gingivalis to identify protein features relevant in biofilm formation
Mohammed, Marwan; Pettersen, Veronika K.; Nerland, Audun Helge; Wiker, Harald Gotten; Bakken, Vidar (Journal article; Peer reviewed, 2021)Background The opportunistic pathogens Fusobacterium nucleatum and Porphyromonas gingivalis are Gram-negative bacteria associated with oral biofilm and periodontal disease. This study investigated interactions between F. ... -
A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease
Martinsen, Einar Marius Hjellestad; Eagan, Tomas Mikal Lind; Wiker, Harald Gotten; Leiten, Elise Orvedal; Husebø, Gunnar Reksten; Knudsen, Kristel Svalland; Tangedal, Solveig; Sanseverino, Walter; Paytuví-Gallart, Andreu; Nielsen, Rune (Journal article; Peer reviewed, 2022-05-12)Background: Few studies have examined the stability of the pulmonary mycobiome. We report longitudinal changes in the oral and pulmonary mycobiome of participants with and without COPD in a large-scale bronchoscopy study ... -
Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable?
Nielsen, Rune; Xue, Yaxin; Jonassen, Inge; Haaland, Ingvild; Kommedal, Øyvind; Wiker, Harald Gotten; Drengenes, Christine; Bakke, Per S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2021)Objective Little is known concerning the stability of the lower airway microbiome. We have compared the microbiota identified by repeated bronchoscopy in healthy subjects and patients with ostructive lung diseaseases ...