Blar i Bergen Open Research Archive på forfatter "Wu, Michael C"

Viser treff 1-4 av 4

    • 450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy 

      Joubert, Bonnie R.; Håberg, Siri Eldevik; Nilsen, Roy Miodini; Wang, Xuting; Vollset, Stein Emil; Murphy, Susan K; Huang, Zhiqing; Hoyo, Cathrine; Midttun, Øivind; Cupul-Uicab, Lea A; Ueland, Per Magne; Wu, Michael C; Nystad, Wenche; Bell, Douglas A; Peddada, Shyamal D; London, Stephanie J (Peer reviewed; Journal article, 2012-10)
      Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple ...

    • DNA Methylation Score as a Biomarker in Newborns for Sustained Maternal Smoking during Pregnancy 

      Reese, Sarah E; Zhao, Shanshan; Wu, Michael C; Joubert, Bonnie R; Parr, Christine Louise; Håberg, Siri Eldevik; Ueland, Per Magne; Nilsen, Roy Miodini; Midttun, Øivind; Vollset, Stein Emil; Peddada, Shyamal D; Nystad, Wenche; London, Stephanie J (Peer reviewed; Journal article, 2017-04)
      Background: Maternal smoking during pregnancy, especially when sustained, leads to numerous adverse health outcomes in offspring. Pregnant women disproportionately underreport smoking and smokers tend to have lower follow-up ...

    • Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns 

      Joubert, Bonnie R; Den Dekker, Herman T; Felix, Janine F; Bohlin, Jon; Ligthart, Symen; Beckett, Emma; Tiemeier, Henning; van Meurs, Joyce B; Uitterlinden, Andre G; Hofman, Albert; Håberg, Siri Eldevik; Reese, Sarah E; Peters, Marjolein J; Kulle Andreassen, Bettina; Steegers, Eric A P; Nilsen, Roy Miodini; Vollset, Stein Emil; Midttun, Øivind; Ueland, Per Magne; Franco, Oscar H; Dehghan, Abbas; De Jongste, Johan C; Wu, Michael C; Wang, Tianyuan; Peddada, Shyamal D; Jaddoe, Vincent W V; Nystad, Wenche; Duijts, Liesbeth; London, Stephanie J (Peer reviewed; Journal article, 2016-02-10)
      Folate is vital for fetal development. Periconceptional folic acid supplementation and food fortification are recommended to prevent neural tube defects. Mechanisms whereby periconceptional folate influences normal development ...

    • Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero 

      Rotroff, Daniel M; Joubert, Bonnie R; Marvel, Skylar W; Håberg, Siri Eldevik; Wu, Michael C; Nilsen, Roy Miodini; Ueland, Per Magne; Nystad, Wenche; London, Stephanie J; Motsinger-Reif, Alison (Peer reviewed; Journal article, 2016-11-25)
      Background: Children exposed to maternal smoking during pregnancy exhibit increased risk for many adverse health effects. Maternal smoking influences methylation in newborns at specific CpG sites (CpGs). Here, we extend ...