Blar i Bergen Open Research Archive på forfatter "Xue, Yaxin"

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    • Development and application of computational methods for NGS-based microbiome research 

      Xue, Yaxin (Doctoral thesis, 2020-11-05)
      The advance of DNA sequencing technologies has dramatically expanded our knowledge of microbial community composition and their functions from diverse environments. The most common Next Generation Sequencing (NGS)-based ...

    • Metagenome-assembled genome distribution and key functionality highlight importance of aerobic metabolism in Svalbard permafrost 

      Xue, Yaxin; Jonassen, Inge; Øvreås, Lise; Tas, Neslihan (Journal article; Peer reviewed, 2020)
      Permafrost underlies a large portion of the land in the Northern Hemisphere. It is proposed to be an extreme habitat and home for cold-adaptive microbial communities. Upon thaw permafrost is predicted to exacerbate increasing ...

    • Metagenomic tools in microbial ecology research 

      Taş, Neslihan; de Jong, Anniek EE; Li, Yaoming; Trubl, Gareth; Xue, Yaxin; Dove, Nicholas C (Journal article; Peer reviewed, 2021)
      Ability to directly sequence DNA from the environment permanently changed microbial ecology. Here, we review the new insights to microbial life gleaned from the applications of metagenomics, as well as the extensive set ...

    • Protected sampling is preferable in bronchoscopic studies of the airway microbiome 

      Grønseth, Rune; Drengenes, Christine; Wiker, Harald G; Tangedal, Solveig; Xue, Yaxin; Husebø, Gunnar; Svanes, Øistein; Lehmann, Sverre; Aardal, Marit Elisabeth; Hoang, Tuyen; Kalananthan, Tharmini; Martinsen, Einar Marius Hjellestad; Leiten, Elise Orvedal; Aanerud, Marianne; Nordeide, Eli; Haaland, Ingvild; Jonassen, Inge; Bakke, Per S.; Eagan, Tomas Mikal (Journal article; Peer reviewed, 2017)
      The aim was to evaluate susceptibility of oropharyngeal contamination with various bronchoscopic sampling techniques. 67 patients with obstructive lung disease and 58 control subjects underwent bronchoscopy with ...

    • Reconstructing ribosomal genes from large scale total RNA meta-transcriptomic data 

      Xue, Yaxin; Lanzén, Anders; Jonassen, Inge (Journal article; Peer reviewed, 2020-03-13)
      Motivation Technological advances in meta-transcriptomics have enabled a deeper understanding of the structure and function of microbial communities. ‘Total RNA’ meta-transcriptomics, sequencing of total reverse transcribed ...

    • Repeated bronchoscopy in health and obstructive lung disease: is the airway microbiome stable? 

      Nielsen, Rune; Xue, Yaxin; Jonassen, Inge; Haaland, Ingvild; Kommedal, Øyvind; Wiker, Harald Gotten; Drengenes, Christine; Bakke, Per S.; Eagan, Tomas Mikal Lind (Journal article; Peer reviewed, 2021)
      Objective Little is known concerning the stability of the lower airway microbiome. We have compared the microbiota identified by repeated bronchoscopy in healthy subjects and patients with ostructive lung diseaseases ...