Browsing Bergen Open Research Archive by Author "Yamada, Shuntaro"
Now showing items 1-11 of 11
-
3D dynamic culture of mesenchymal stem cells under fluid flow : Implications for bone regeneration
Yamada, Shuntaro (Doctoral thesis, 2023-10-06)Skjebnen og veksten til mesenkymale stamceller (MSC) kan påvirkes av biologiske stimuli. I benvev regnes skjærspenning fra væske forårsaket av interstitiell væskestrøm som den primære mekaniske stimulien på celleplan, som ... -
Efficacy of treating segmental bone defects through endochondral ossification: 3D printed designs and bone metabolic activities
Hara, Kenji; Hellem, Endre; Yamada, Shuntaro; Sariibrahimoglu, Kemal; Mølster, Anders; Gjerdet, Nils Roar; Hellem, Sølve; Mustafa, Kamal Babikeir Elnour; Yassin, Mohammed Ahmed Alamin Yousif (Journal article; Peer reviewed, 2022)Three-dimensional printing (3D printing) is a promising technique for producing scaffolds for bone tissue engineering applications. Porous scaffolds can be printed directly, and the design, shape and porosity can be ... -
Harnessing the Antioxidative Potential of Dental Pulp Stem Cell-Conditioned Medium in Photopolymerized GelMA Hydrogels
Yamada, Shuntaro; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Torelli, Francesco; Angelova Volponi, Ana; Sandven, Linda; Ueda, Minoru; Fristad, Inge; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2024)Gelatin methacryloyl (GelMA) stands out for its biocompatibility, tunability, and functionality, being often selected as a scaffolding material. However, the biological modulations induced by its photocrosslinking process ... -
Hybrid material based on hyaluronan hydrogels and poly(l-lactide-co-1,3-trimethylene carbonate) scaffolds toward a cell-instructive microenvironment with long-term in vivo degradability
Kivijärvi, Tove; Goksøyr, Øyvind; Yassin, Mohammed Ahmed Alamin Yousif; Jain, Shubham; Yamada, Shuntaro; Mustafa, Kamal Babikeir Elnour; Finne-Wistranda, Anna (Journal article; Peer reviewed, 2022)Degradable polyester-based scaffolds are ideal for tissue engineering applications where long-term structural integrity and mechanical support are a requisite. However, their hydrophobic and unfunctionalized surfaces ... -
Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor
Yamada, Shuntaro; Yassin, Mohammed Ahmed; Schwarz, Thomas; Hansmann, Jan; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021)The fatal determination of bone marrow mesenchymal stem/stromal cells (BMSC) is closely associated with mechano-environmental factors in addition to biochemical clues. The aim of this study was to induce osteogenesis in ... -
Optimisation and validation of a custom-designed perfusion bioreactor for bone tissue engineering: Flow assessment and optimal culture environmental conditions
Yamada, Shuntaro; Yassin, Mohammed Ahmed Alamin Yousif; Schwarz, Thomas; Mustafa, Kamal Babikeir Elnour; Hansmann, Jan (Journal article; Peer reviewed, 2022)Various perfusion bioreactor systems have been designed to improve cell culture with three-dimensional porous scaffolds, and there is some evidence that fluid force improves the osteogenic commitment of the progenitors. ... -
Photo-Clickable Triazine-Trione Thermosets as Promising 3D Scaffolds for Tissue Engineering Applications
Johansen, Åshild; Yamada, Shuntaro; Yassin, Mohammed Ahmed Alamin Yousif; Gjengedal, Gudveig Cecilie Gjerde; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2024)There is an overwhelming demand for new scaffolding materials for tissue engineering (TE) purposes. Polymeric scaffolds have been explored as TE materials; however, their high glass transition state (Tg) limits their ... -
Scaffolds in Periodontal Regenerative Treatment
Yamada, Shuntaro; Shanbhag, Siddharth; Mustafa, Kamal Babikeir Elnour (Journal article, 2021) -
Surface activation with oxygen plasma promotes osteogenesis with enhanced extracellular matrix formation in three- dimensional microporous scaffolds
Yamada, Shuntaro; Yassin, Mohammed Ahmed; Weigel, Tobias; Schmitz, Tobias; Hansmann, Jan; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2021)Various types of synthetic polyesters have been developed as biomaterials for tissue engineering. These materials commonly possess biodegradability, biocompatibility, and formability, which are preferable properties for ... -
Translation of Biophysical Environment in Bone into Dynamic Cell Culture under Flow for Bone Tissue Engineering
Yamada, Shuntaro; Niklas Ockermann, Philipp; Schwarz, Thomas; Mustafa, Kamal Babikeir Elnour; Hansmann, Jan (Journal article; Peer reviewed, 2023)Bone is a dynamic environment where osteocytes, osteoblasts, and mesenchymal stem/progenitor cells perceive mechanical cues and regulate bone metabolism accordingly. In particular, interstitial fluid flow in bone and bone ... -
Unique osteogenic profile of bone marrow stem cells stimulated in perfusion bioreactor is Rho-ROCK-mediated contractility dependent
Yamada, Shuntaro; Yassin, Mohammed Ahmed; Torelli, Francesco; Hansmann, Jan; Green, Jeremy; Mustafa, Kamal (Journal article; Peer reviewed, 2023)The fate determination of bone marrow mesenchymal stem/stromal cells (BMSC) is tightly regulated by mechanical cues, including fluid shear stress. Knowledge of mechanobiology in 2D culture has allowed researchers in bone ...