Browsing Bergen Open Research Archive by Author "Yassin, Mohammed Ahmed Alamin Yousif"
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Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial
Gjerde, Cecilie Gudveig; Mustafa, Kamal Babikeir Eln; Hellem, Sølve; Rojewski, Markus; Gjengedal, Harald; Yassin, Mohammed Ahmed Alamin Yousif; Feng, Xin; Skaale, Siren G; Berge, Trond Inge; Rosén, Annika; Shi, Xieqi; Ahmed, Aymen B; Gjertsen, Bjørn Tore; Schrezenmeier, Hubert; Layrolle, Pierre (Journal article; Peer reviewed, 2018)Background Autologous grafting, despite some disadvantages, is still considered the gold standard for reconstruction of maxillofacial bone defects. The aim of this study was to evaluate bone regeneration using bone ... -
Delivery of VEGFA in bone marrow stromal cells seeded in copolymer scaffold enhances angiogenesis, but is inadequate for osteogenesis as compared with the dual delivery of VEGFA and BMP2 in a subcutaneous mouse model
Sharma, Sunita; Sapkota, Dipak; Xue, Ying; Rajthala, Saroj; Yassin, Mohammed Ahmed Alamin Yousif; Finne-Wistrand, Anna; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2018-01-31)Background: In bone tissue engineering (BTE), extensive research into vascular endothelial growth factor A (VEGFA)-mediated angiogenesis has yielded inconsistent results. The aim of this study was to investigate the influence ... -
Ectopic Bone Tissue Engineering in Mice Using Human Gingiva or Bone Marrow-Derived Stromal/Progenitor Cells in Scaffold-Hydrogel Constructs
Shanbhag, Siddharth; Kampleitner, Carina; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Yassin, Mohammed Ahmed Alamin Yousif; Dongre, Harsh Nitin; Costea, Daniela Elena; Tangl, Stefan; Stavropoulos, Andreas; Bolstad, Anne Isine; Suliman, Salwa; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021-11-30)Three-dimensional (3D) spheroid culture can promote the osteogenic differentiation and bone regeneration capacity of mesenchymal stromal cells (MSC). Gingiva-derived progenitor cells (GPC) represent a less invasive alternative ... -
Optimisation and validation of a custom-designed perfusion bioreactor for bone tissue engineering: Flow assessment and optimal culture environmental conditions
Yamada, Shuntaro; Yassin, Mohammed Ahmed Alamin Yousif; Schwarz, Thomas; Mustafa, Kamal Babikeir Elnour; Hansmann, Jan (Journal article; Peer reviewed, 2022)Various perfusion bioreactor systems have been designed to improve cell culture with three-dimensional porous scaffolds, and there is some evidence that fluid force improves the osteogenic commitment of the progenitors. ... -
Understanding of how the properties of medical grade lactide based copolymer scaffolds influence adipose tissue regeneration: Sterilization and a systematic in vitro assessment
Jain, Shubham; Yassin, Mohammed Ahmed Alamin Yousif; Fuoco, Tiziana; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Vindenes, Hallvard; Mustafa, Kamal Babikeir Elnour; Finne-Wistand, Anna (Journal article; Peer reviewed, 2021)Aliphatic polyesters are the synthetic polymers most commonly used in the development of resorbable medical implants/devices. Various three-dimensional (3D) scaffolds have been fabricated from these polymers and used in ...