Blar i Bergen Open Research Archive på forfatter "Yuan, Xing"
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Intensified Impacts of Central Pacific ENSO on the Reversal of December and January Surface Air Temperature Anomaly over China since 1997
Li, Hua; Fan, Ke; He, Shengping; Liu, Yong; Yuan, Xing; Wang, Huijun (Journal article; Peer reviewed, 2021)The reversal of surface air temperature anomalies (SATA) in winter brings a great challenge for short-term climate prediction, and the mechanisms are not well understood. This study found that the reversal of SATA between ... -
Novel STAT3 Inhibitors Targeting STAT3 Dimerization by Binding to the STAT3 SH2 Domain
Hua, Yaping; Yuan, Xing; Shen, Yun-Heng; Wang, Jinxin; Azeem, Waqas; Yang, Shuo; Gade, Alexandra; Lellahi, Seyed Mohammad; Øyan, Anne Margrete; Ke, Xisong; Zhang, Wei-Dong; Kalland, Karl Henning (Journal article; Peer reviewed, 2022)Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity responsive target ... -
Recent Intensified Influence of the Winter North Pacific Sea Surface Temperature on the Mei-Yu Withdrawal Date
Li, Hua; He, Shengping; Fan, Ke; Liu, Yong; Yuan, Xing (Journal article; Peer reviewed, 2021)The mei-yu withdrawal date (MWD) is a crucial indicator of flood/drought conditions over East Asia. It is characterized by a strong interannual variability, but its underlying mechanism remains unknown. We investigated the ...