Blar i Bergen Open Research Archive på forfatter "Zannad, Faiez"
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Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure
Markousis-Mavrogenis, George; Minich, Waldemar B.; Al-Mubarak, Ali A.; Anker, Stefan D.; Cleland, John G. F.; dickstein, kenneth; Lang, Chim C.; Ng, Leong L.; Samani, Nilesh J.; Zannad, Faiez; Metra, Marco; Seemann, Petra; Hoeg, Antonia; Lopez, Patricio; Van Veldhuisen, Dirk J.; De Boer, Rudolf A.; Voors, Adriaan A.; Van Der Meer, Peter; Schomburg, Lutz; Bomer, Nils (Journal article; Peer reviewed, 2023)Aims The importance of autoantibodies (AABs) against adrenergic/muscarinic receptors in heart failure (HF) is not well-understood. We investigated the prevalence and clinical/prognostic associations of four AABs recognizing ... -
Clinical impact of changes in mitral regurgitation severity after medical therapy optimization in heart failure
Pagnesi, Matteo; Adamo, Marianna; Sama, Iziah E.; Anker, Stefan D.; Cleland, John G.; Dickstein, Kenneth; Filippatos, Gerasimos S.; Inciardi, Riccardo M.; Lang, Chim C.; Lombardi, Carlo; Ng, Leong L.; Ponikowski, Piotr; Samani, Nilesh J.; Zannad, Faiez; van Veldhuisen, Dirk J.; Voors, Adriaan A.; Metra, Marco (Journal article; Peer reviewed, 2022)Background: Few data are available regarding changes in mitral regurgitation (MR) severity with guideline-recommended medical therapy (GRMT) in heart failure (HF). Our aim was to evaluate the evolution and impact of MR ... -
Clinical implications of left atrial changes after optimization of medical therapy in patients with heart failure
Inciardi, Riccardo M.; Pagnesi, Matteo; Lombardi, Carlo M.; Anker, Stefan D.; Cleland, John G.; Dickstein, Kenneth; Filippatos, Gerasimos S.; Lang, Chim C.; Ng, Leong L.; Pellicori, Pierpaolo; Ponikowski, Piotr; Samani, Nilesh J.; Zannad, Faiez; van Veldhuisen, Dirk J.; Solomon, Scott D.; Voors, Adriaan A.; Metra, Marco (Journal article; Peer reviewed, 2022)Aims Limited data exist regarding the prognostic relevance of changes in left atrial (LA) dimensions in patients with heart failure (HF). We assessed changes in LA dimension and their relation with outcomes after optimization ... -
Impact of mitral regurgitation in patients with worsening heart failure: insights from BIOSTAT-CHF
Pagnesi, Matteo; Adamo, Marianna; Sama, Iziah E.; Anker, Stefan D.; Cleland, John G.; Dickstein, Kenneth; Filippatos, Gerasimos S.; Lang, Chim C.; Ng, Leong L.; Ponikowski, Piotr; Ravera, Alice; Samani, Nilesh J.; Zannad, Faiez; van Veldhuisen, Dirk J.; Voors, Adriaan A.; Metra, Marco (Journal article; Peer reviewed, 2021)Aims Few data regarding the prevalence and prognostic impact of mitral regurgitation (MR) in patients with worsening chronic or new-onset acute heart failure (HF) are available. We investigated the role of MR in the BIOlogy ... -
Machine learning based on biomarker profiles identifies distinct subgroups of heart failure with preserved ejection fraction
Woolley, Rebecca J.; Ceelen, Daan; Ouwerkerk, Wouter; Tromp, Jasper; Figarska, Sylwia M.; Anker, Stefan D.; Dickstein, Kenneth; Filippatos, Gerasimos; Zannad, Faiez; Marco, Metra; Ng, Leong L.; Samani, Nilesh J.; van Veldhuisen, Dirk J; Lang, Chim C.; Lam, Carolyn S.P.; Voors, Adriaan A. (Journal article; Peer reviewed, 2021)Aims The lack of effective therapies for patients with heart failure with preserved ejection fraction (HFpEF) is often ascribed to the heterogeneity of patients with HFpEF. We aimed to identify distinct pathophysiologic ... -
Pathophysiological pathways in patients with heart failure and atrial fibrillation
Santema, Bernadet T.; Arita, Vicente Artola; Sama, Iziah E.; Kloosterman, Mariëlle; van den Berg, Maarten P.; Nienhuis, Hans L.A.; Van Gelder, Isabelle C.; van der Meer, Peter; Zannad, Faiez; Metra, Marco; Ter Maaten, Jozine M.; Cleland, John G.; Ng, Leong L.; Anker, Stefan D.; Lang, Chim C.; Samani, Nilesh J.; Dickstein, Kenneth; Filippatos, Gerasimos; van Veldhuisen, Dirk J.; Lam, Carolyn S.P.; Rienstra, Michiel; Voors, Adriaan A. (Journal article; Peer reviewed, 2022)Aims Atrial fibrillation (AF) and heart failure (HF) are two growing epidemics that frequently co-exist. We aimed to gain insights into the underlying pathophysiological pathways in HF patients with AF by comparing ... -
Perceived risk profile and treatment optimization in heart failure: an analysis from BIOlogy Study to TAilored Treatment in chronic heart failure
Kobayashi, Masatake; Voors, Adriaan A.; Ouwerkerk, Wouter; Duarte, Kevin; Girerd, Nicolas; Rossignol, Patrick; Metra, Marco; Lang, Chim C.; Ng, Leong L.; Filippatos, Gerasimos; Dickstein, Kenneth; van Veldhuisen, Dirk J.; Zannad, Faiez; Ferreira, João Pedro (Journal article; Peer reviewed, 2021)Background Achieving target doses of angiotensin-converting-enzyme inhibitor/angiotensin-receptor blockers (ACEi/ARB) and beta-blockers in heart failure with reduced ejection fraction (HFrEF) is often underperformed. In ... -
Quality of life in men and women with heart failure: association with outcome, and comparison between the Kansas City Cardiomyopathy Questionnaire and the EuroQol 5 dimensions questionnaire
Ravera, Alice; Santema, Bernadet T.; Sama, Iziah E.; Meyer, Sven; Lombardi, Carlo; Carubelli, Valentina; Ferreira, João Pedro; Lang, Chim C.; Dickstein, Kenneth; Anker, Stefan D.; Samani, Nilesh J.; Zannad, Faiez; van Veldhuisen, Dirk J.; Teerlink, John R.; Metra, Marco; Voors, Adriaan A. (Journal article; Peer reviewed, 2021)Aims We sought to analyse quality of life (QoL) measures derived from two questionnaires widely used in clinical trials, the Kansas City Cardiomyopathy Questionnaire (KCCQ) and the EuroQoL 5 dimensions (EQ-5D), and to ... -
Urinary Marker Profiles in Heart Failure with Reduced Versus Preserved Ejection Fraction
Streng, Koen W.; Hillege, Hans L.; ter Maaten, Jozine M.; van Veldhuisen, Dirk J.; Dickstein, Kenneth; Samani, Nilesh J.; Ng, Leong L.; Metra, Marco; Filippatos, Gerasimos S.; Ponikowski, Piotr; Zannad, Faiez; Anker, Stefan D.; van der Meer, Peter; Lang, Chim C.; Voors, Adriaan A.; Damman, Kevin (Journal article; Peer reviewed, 2023)Background Recent data suggest different causes of renal dysfunction between heart failure with reduced (HFrEF) versus preserved ejection fraction (HFpEF). We therefore studied a wide range of urinary markers reflecting ... -
The value of spot urinary creatinine as a marker of muscle wasting in patients with new-onset or worsening heart failure
Pandhi, Paloma; Streng, Koen W.; Anker, Stefan D.; Cleland, John G.; Damman, Kevin; Dickstein, Kenneth; Pellicori, Pierpaolo; Lang, Chim C.; Ng, Leong; Samani, Nilesh J.; Zannad, Faiez; Metra, Marco; Rossignol, Patrick; Filippatos, Gerasimos; van Veldhuisen, Dirk J.; Voors, Adriaan A.; ter Maaten, Jozine M. (Journal article; Peer reviewed, 2021)Background Muscle wasting and unintentional weight loss (cachexia) have been associated with worse outcomes in heart failure (HF), but timely identification of these adverse phenomena is difficult. Spot urinary creatinine ...