Browsing Bergen Open Research Archive by Author "Zetterberg, Henrik"

Now showing items 1-6 of 6

    • Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID‑19 

      Aamodt, Anne Hege; Høgestøl, Einar August; Popperud, Trine Haug; Holter, Jan Cato; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Stiksrud, Birgitte; Berge, Tone; Barratt-Due, Andreas; Aukrust, Pål; Heggelund, Lars; Blennow, Kaj; Zetterberg, Henrik; Harbo, Hanne Flinstad; Quist‑Paulsen, Else (Journal article; Peer reviewed, 2021)
      Objective To test the hypotheses that blood biomarkers for nervous system injury, serum concentrations of neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAp) can serve as biomarkers for ...

    • Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip fracture patients 

      Watne, Leiv Otto; Pollmann, Christian Thomas; Neerland, Bjørn Erik; Quist-Paulsen, Else; Halaas, Nathalie Bodd; Idland, Ane-Victoria; Hassel, Bjørnar; Henjum, Kristi; Knapskog, Anne Brita; Frihagen, Frede; Ræder, Johan; Godø, Aasmund; Ueland, Per Magne; McCann, Adrian; Figved, Paul Wender; Selbæk, Geir; Zetterberg, Henrik; Fei Fang, Evandro; Myrstad, Marius; Giil, Lasse Melvær (Journal article; Peer reviewed, 2022)
      Background: The kynurenine pathway (KP) has been identified as a potential mediator linking acute illness to cognitive dysfunction by generating neuroactive metabolites in response to inflammation. Delirium (acute confusion) ...

    • Genome-wide meta-analysis for Alzheimer’s disease cerebrospinal fluid biomarkers 

      Jansen, Iris E.; van der Lee, Sven J.; Gomez-Fonseca, Duber; de Rojas, Itziar; Dalmasso, Maria Carolina; Grenier-Boley, Benjamin; Athanasiu, Lavinia; Bahrami, Shahram; Bergh, Sverre; Djurovic, Srdjan; Fladby, Tormod; Jarholm, Jonas Alexander; Knapskog, Anne Brita; Pålhaugen, Lene; Saltvedt, Ingvild; Selbæk, Geir; Selnes, Per; Andreassen, Ole; Shadrin, Alexey; Skoog, Ingmar; Soininen, Hilkka; Tsolaki, Magda; Van Broeckhoven, Christine; Van Dongen, Jasper; van Swieten, John C.; Vandenberghe, Rik; Vidal, Jean-Sébastien; Visser, Pieter J.; Vogelgsang, Jonathan; Waern, Margda; Wagner, Michael; Wiltfang, Jens; Wittens, Mandy M.J.; Zetterberg, Henrik; Zulaica, Miren; van Duijn, Cornelia M.; Bjerke, Maria; Engelborghs, Sebastiaan; Jessen, Frank; Teunissen, Charlotte E.; Pastor, Pau; Hiltunen, Mikko; Ingelsson, Martin; Clarimón, Jordi; Sleegers, Kristel; Ruiz, Agustín; Ramirez, Alfredo; Cruchaga, Carlos; Lambert, Jean-Charles; van der Flier, Wiesje M. (Journal article; Peer reviewed, 2022)
      Amyloid-beta 42 (Aβ42) and phosphorylated tau (pTau) levels in cerebrospinal fluid (CSF) reflect core features of the pathogenesis of Alzheimer’s disease (AD) more directly than clinical diagnosis. Initiated by the European ...

    • Neurofilament and Brain Atrophy and Their Association with Cognition in Multiple Sclerosis: A 10-Year Follow-Up Study 

      Bhan, Alok; Jacobsen, Cecilie; Dalen, Ingvild; Alves, Guido Werner; Bergsland, Niels; Myhr, Kjell-Morten; Zetterberg, Henrik; Zivadinov, Robert; Farbu, Elisabeth (Journal article; Peer reviewed, 2023)
      Introduction. Cognitive impairment is an important contributor to disability in multiple sclerosis (MS). Disconnection of neuronal circuits due to axonal injury is probably an important underlying mechanism for this ...

    • Neurofilament light is a biomarker of brain involvement in lupus and primary Sjögren’s syndrome 

      Tjensvoll, Anne Bolette; Lauvsnes, Maria Boge; Zetterberg, Henrik; Kvaløy, Jan Terje; Kvivik, Ingeborg; Maroni, Stian; Greve, Ole Jacob; Beyer, Mona K.; Hirohata, Shunsei; Putterman, Chaim; Alves, Guido Werner; Harboe, Erna; Blennow, Kaj; Gøransson, Lasse; Omdal, Roald (Journal article; Peer reviewed, 2020)
      Background To test the hypothesis that neurofilament light (NfL) in CSF is a biomarker of CNS involvement in patients with systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS), we measured NfL in CSF ...

    • Preanalytical stability of plasma biomarkers for Alzheimer's disease pathology 

      Sunde, Anita Lenora; Alsnes, Ingvild Vatten; Årsland, Dag; Ashton, Nicholas J.; Tovar-Rios, Diego Alejandro; De Santis, Giovanni; Blennow, Kaj; Zetterberg, Henrik; Kjosavik, Svein Reidar (Journal article; Peer reviewed, 2023)
      Introduction Plasma tests have demonstrated high diagnostic accuracy for identifying Alzheimer's disease pathology. To facilitate the transition to clinical utility, we assessed whether plasma storage duration and ...