Blar i Bergen Open Research Archive på forfatter "Zhang, Hongyu"
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Bidirectional Dysregulation of AMPA Receptor-Mediated Synaptic Transmission and Plasticity in Brain Disorders
Zhang, Hongyu; Bramham, Clive R. (Journal article; Peer reviewed, 2020-07-10)AMPA receptors (AMPARs) are glutamate-gated ion channels that mediate the majority of fast excitatory synaptic transmission throughout the brain. Changes in the properties and postsynaptic abundance of AMPARs are pivotal ... -
Propofol alleviates DNA damage induced by oxygen glucose deprivation and reperfusion via FoxO1 nuclear translocation in H9c2 cells
Zhou, Dandan; Zhuang, Jinqiang; Wang, Yihui; Zhao, Dandan; Zhao, Lidong; Zhu, Shun; Pu, Jinjun; Yin, Ming; Zhang, Hongyu; Wang, Zejian; Hong, Jiang (Peer reviewed; Journal article, 2019-03-15)Ischemia/reperfusion (I/R) injury induces irreversible oxidative stress damage to the cardiac myocytes. Many studies have revealed that propofol alleviates the important organelle-mediated injury from oxidative stress in ... -
Propofol ameliorates H9c2 cells apoptosis induced by oxygen glucose deprivation and reperfusion injury via inhibiting high levels of mitochondrial fusion and fission
Zhao, Lidong; Zhuang, Jinqiang; Wang, Yihui; Zhou, Dandan; Zhao, Dandan; Zhu, Shun; Pu, Jinjun; Zhang, Hongyu; Yin, Ming; Zhao, Wenjuan; Wang, Zejian; Hong, Jiang (Peer reviewed; Journal article, 2019-02-12)Background: The cardioprotective effect of propofol on ischemia-reperfusion injury (I/R injury) is partly due to suppressing apoptosis. Mitochondrial dynamics are also involved in apoptosis. Mitochondrial fusion and fission ...