Browsing Bergen Open Research Archive by Author "Zwart, John-Anker"
Now showing items 1-19 of 19
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Age of menarche is associated with knee joint replacement due to primary osteoarthritis (The HUNT Study and the Norwegian Arthroplasty Register)
Hellevik, Alf Inge; Nordsletten, Lars; Johnsen, Marianne Bakke; Fenstad, Anne Marie; Furnes, Ove; Storheim, Kjersti; Zwart, John-Anker; Flugsrud, Gunnar B; Langhammer, Arnulf (Peer reviewed; Journal article, 2017-10)Objective: To investigate whether parity, age at menarche, menopausal status, age at menopause, use of oral contraceptives (OC) or use of hormone replacement therapy (HRT) were associated with total knee replacement (TKR) ... -
Association between body height and chronic low back pain: a follow-up in the Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Peer reviewed; Journal article, 2015-06-15)Objective: To study potential associations between body height and subsequent occurrence of chronic low back pain (LBP). Design: Prospective cohort study. Setting: The North-Trøndelag Health Study (HUNT). Data were ... -
Associations between the number of children, age at childbirths and prevalence of chronic low back pain: the Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Storheim, Kjersti; Zwart, John-Anker (Journal article; Peer reviewed, 2020)Background Associations between childbirths and subsequent risk of low back pain (LBP) have not been clarified. Changes in sex hormone levels or lumbar posture during pregnancy may have an impact on LBP later in life. The ... -
The causal role of smoking on the risk of hip or knee replacement due to primary osteoarthritis: a Mendelian randomisation analysis of the HUNT study
Johnsen, Marianne Bakke; Vie, Gunnhild Åberge; Winsvold, Bendik K S; Bjørngaard, Johan Håkon; Åsvold, Bjørn Olav; Gabrielsen, Maiken Elvestad; Pedersen, Linda Margareth; Hellevik, Alf Inge; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Skorpen, Frank; Romundstad, Pål Richard; Storheim, Kjersti; Nordsletten, Lars; Zwart, John-Anker (Peer reviewed; Journal article, 2017-06)Objective: Smoking has been associated with a reduced risk of hip and knee osteoarthritis (OA) and subsequent joint replacement. The aim of the present study was to assess whether the observed association is likely to be ... -
Clinical effect modifiers of antibiotic treatment in patients with chronic low back pain and Modic changes - secondary analyses of a randomised, placebocontrolled trial (the AIM study)
Bråten, Lars Christian Haugli; Grøvle, Lars; Espeland, Ansgar; Pripp, Are Hugo; Grotle, Margreth; Hellum, Christian; Haugen, Anne Julsrud; Froholdt, Anne; Rolfsen, Mads Peder; Nygaard, Øystein Petter; Lutro, Olav; Kristoffersen, Per Martin; Anke, Audny; Schistad, Ellina Iordanova; Skouen, Jan Sture; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (Journal article; Peer reviewed, 2020)Background Randomised trials on antibiotic treatment for patients with chronic low back pain and vertebral endplate changes visible on MRI (Modic changes) have shown mixed results. A possible explanation might be a real ... -
A Comparison of Anthropometric Measures for Assessing the Association between Body Size and Risk of Chronic Low Back Pain: TheHUNT Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Peer reviewed; Journal article, 2015-10-27)Background: Previous work indicates that overweight and obese individuals carry an increased risk of experiencing chronic low back pain (LBP). It is not known, however, how the association with body size depends on the ... -
Cost–utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study)
Grotle, Margreth; Bråten, Lars Christian Haugli; Brox, Jens Ivar; Espeland, Ansgar; Zolic-Karlsson, Zinajda; Killingmo, Rikke Munk; Tingulstad, Alexander; Grøvle, Lars; Johanessen, Anne Froholdt; Kristoffersen, Per Martin; Wigemyr, Monica; van Tulder, Maurits W.; Storheim, Kjersti; Zwart, John-Anker (Journal article; Peer reviewed, 2020)Objective To evaluate the cost–utility of 100 days of antibiotics in patients with chronic low back pain (LBP) and type I or II Modic changes included in the Antibiotic treatment In patients with chronic low back pain ... -
Do abnormal serum lipid levels increase the risk of chronic low back pain? The Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Peer reviewed; Journal article, 2014-09-18)Background: Cross-sectional studies suggest associations between abnormal lipid levels and prevalence of low back pain (LBP), but it is not known if there is any causal relationship. Objective: The objective was to determine, ... -
Does diabetes influence the probability of experiencing chronic low back pain? A population-based cohort study: the Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Sørgjerd, Elin Pettersen; Åsvold, Bjørn Olav; Zwart, John-Anker (Peer reviewed; Journal article, 2019)Objective: Low back pain (LBP) is a major problem in modern society and it is important to study possible risk factors for this disorder. People with diabetes are often affected by LBP, but whether diabetes represents a ... -
The effect of infliximab in patients with chronic low back pain and Modic changes (the BackToBasic study): study protocol of a randomized, double blind, placebo-controlled, multicenter trial
Gjefsen, Elisabeth; Bråten, Lars Christian Haugli; Goll, Guro Løvik; Wigemyr, Monica; Bolstad, Nils; Valberg, Morten; Schistad, Ellina Iordanova; Marchand, Gunn Hege; Granviken, Fredrik; Selmer, Kaja Kristine; Johanessen, Anne Froholdt; Haugen, Anne Julsrud; Dagestad, Magnhild Hammersland; Vetti, Nils; Bakland, Gunnstein; Lie, Benedicte Alexandra; Haavardsholm, Espen A.; Nilsen, Aksel Thuv; Holmgard, Thor Einar; Kadar, Thomas; Kvien, Tore Kristian; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Espeland, Ansgar; Storheim, Kjersti; Zwart, John-Anker (Journal article; Peer reviewed, 2020)Background Low back pain is common and a significant number of patients experience chronic low back pain. Current treatment options offer small to moderate effects. Patients with vertebral bone marrow lesions visualized ... -
Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial
Bråten, Lars Christian Haugli; Rolfsen, Mads Peder; Espeland, Ansgar; Wigemyr, Monica; Assmus, Jörg; Froholdt, Anne; Haugen, Anne Julsrud; Marchand, Gunn Hege; Kristoffersen, Per M; Lutro, Olav; Randen, Sigrun; Wilhelmsen, Maja; Winsvold, Bendik K S; Kadar, Thomas; Holmgard, Thor Einar; Vigeland, Maria Dehli; Vetti, Nils; Nygaard, Øystein Petter; Lie, Benedicte Alexandra; Hellum, Christian; Anke, Audny; Grotle, Margreth; Schistad, Ellina Iordanova; Skouen, Jan Sture; Grøvle, Lars; Brox, Jens Ivar; Zwart, John-Anker; Storheim, Kjersti (Peer reviewed; Journal article, 2019)Objective To assess the efficacy of three months of antibiotic treatment compared with placebo in patients with chronic low back pain, previous disc herniation, and vertebral endplate changes (Modic changes). Design Double ... -
Incidence of total hip or knee replacement due to osteoarthritis in relation to thyroid function: a prospective cohort study (The Nord-Trøndelag Health Study)
Hellevik, Alf Inge; Johnsen, Marianne Bakke; Langhammer, Arnulf; Fenstad, Anne Marie; Furnes, Ove; Storheim, Kjersti; Zwart, John-Anker; Flugsrud, Gunnar B; Nordsletten, Lars (Peer reviewed; Journal article, 2017-05-18)Background: To study whether thyroid function was associated with risk of hip or knee replacement due to primary osteoarthritis. Methods: In a prospective cohort study, data from the second and third survey of the ... -
Is chronic low back pain a risk factor for diabetes? The Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Sørgjerd, Elin Pettersen; Åsvold, Bjørn Olav; Zwart, John-Anker (Peer reviewed; Journal article, 2018)Objective: The purpose of this study was to examine the risk of diabetes associated with the presence or absence of chronic low back pain, considering both cross-sectional and cohort data. Research design and methods: ... -
Is there a U-shaped relationship between physical activity in leisure time and risk of chronic low back pain? A follow-up in the HUNT Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Peer reviewed; Journal article, 2016-04-11)Background: Physical activity in leisure time is often considered to have favourable effects on the risk of low back pain (LBP), but demonstrating a definite association in epidemiological studies has proven difficult. The ... -
Is there an Association between vitamin D status and risk of chronic low back pain? A nested case-Control analysis in the Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Mai, Xiao-Mei; Langhammer, Arnulf; Zwart, John-Anker (Peer reviewed; Journal article, 2017-11-25)Objectives: To explore potential associations between vitamin D status and risk of chronic low back pain (LBP) in a Norwegian cohort, and to investigate whether relationships depend on the season of blood sample collection. ... -
The mediating effect of body mass index on the relationship between smoking and hip or knee replacement due to primary osteoarthritis. A population-based cohort study (the HUNT study)
Johnsen, Marianne Bakke; Hellevik, Alf Inge; Småstuen, Milada C; Langhammer, Arnulf; Furnes, Ove; Flugsrud, Gunnar B; Nordsletten, Lars; Zwart, John-Anker; Storheim, Kjersti (Peer reviewed; Journal article, 2017-12-28)To investigate the total effect of smoking on total hip or knee replacement (THR/TKR) due to primary osteoarthritis (OA) and to quantify the indirect effect of smoking through body mass index (BMI). Participants from the ... -
Metabolic syndrome as a risk factor for total hip or knee replacement due to primary osteoarthritis: A prospective cohort study (the HUNT study and the Norwegian arthroplasty register)
Hellevik, Alf Inge; Johnsen, Marianne Bakke; Langhammer, Arnulf; Baste, Valborg; Furnes, Ove; Storheim, Kjersti; Zwart, John-Anker; Flugsrud, Gunnar B; Nordsletten, Lars (Peer reviewed; Journal article, 2018-01-10)Objective: Biochemical changes associated with obesity may accelerate osteoarthritis beyond the effect of mechanical factors. This study investigated whether metabolic syndrome and its components (visceral obesity, ... -
Oedema on STIR modified the effect of amoxicillin as treatment for chronic low back pain with Modic changes—subgroup analysis of a randomized trial
Kristoffersen, Per M; Bråten, Lars Christian Haugli; Vetti, Nils; Grøvle, Lars; Hellum, Christian; Storheim, Kjersti; Zwart, John-Anker; Assmus, Jörg; Espeland, Ansgar (Journal article; Peer reviewed, 2021)Objective To evaluate potential MRI-defined effect modifiers of amoxicillin treatment in patients with chronic low back pain and type 1 or 2 Modic changes (MCs) at the level of a previous lumbar disc herniation (index ... -
Physical activity level at work and risk of chronic low back pain: A follow-up in the Nord-Trøndelag Health Study
Heuch, Ingrid; Heuch, Ivar; Hagen, Knut; Zwart, John-Anker (Peer reviewed; Journal article, 2017-04-10)Background: Physical activity in leisure time seems to reduce the risk of low back pain, but it is not known whether occupational activity, as recorded in a representative working population, produces a higher or lower ...