• Cumulative prognostic score predicting mortality in patients older than 80 years admitted to the ICU 

      de Lange, Dylan W.; Brinkman, Sylvia; Flaatten, Hans; Boumendil, Ariane; Morandi, Alessandro; Andersen, Finn Husøy; Artigas, Antonio; Bertolini, Guido; Cecconi, Maurizio; Christensen, Steffen; Faraldi, Loredana; Fjølner, Jesper; Jung, Christian; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Bollen Pinto, Bernardo; de Smet, Anne Marie G.A.; Soliman, Ivo W.; Szczeklik, Wojciech; Valentin, Andreas; Watson, Ximena; Zafeiridis, Tilemachos; Guidet, Bertrand (Peer reviewed; Journal article, 2019-06)
      OBJECTIVES To develop a scoring system model that predicts mortality within 30 days of admission of patients older than 80 years admitted to intensive care units (ICUs). DESIGN Prospective cohort study. SETTING A total of ...
    • Huge variation in obtaining ethical permission for a non-interventional observational study in Europe 

      de Lange, Dylan W.; Guidet, Bertrand R.; Andersen, Finn Husøy; Artigas, Antonio; Bertolini, Guido; Moreno, Rui; Christensen, Steffen; Cecconi, Maurizio; Agvald-Öhman, Christina; Gradišek, Primož; Jung, Christian; Marsh, Brian J.; Oeyen, Sandra; Bollen Pinto, Bernardo; Szczeklik, Wojciech; Watson, Ximena; Zafeiridis, Tilemachos; Flaatten, Hans (Peer reviewed; Journal article, 2019-06-03)
      Background Ethical approval (EA) must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Methods Sixteen European national ...
    • Relationship between the Clinical Frailty Scale and short‑term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study. 

      Fronczek, Jakub; Polok, Kamil; de Lange, Dylan W.; Jung, Christian; Beil, Michael; Rhodes, Andrew; Fjølner, Jesper; Górka, Jacek; Andersen, Finn H.; Artigas, Antonio; Cecconi, Maurizio; Christensen, Steffen; Flaatten, Hans; Szczeklik, Wojciech (Journal article; Peer reviewed, 2021)
      Background: The Clinical Frailty Scale (CFS) is frequently used to measure frailty in critically ill adults. There is wide variation in the approach to analysing the relationship between the CFS score and mortality after ...
    • Reliability of the Clinical Frailty Scale in very elderly ICU patients: a prospective European study 

      Flaatten, Hans; Guidet, Bertrand; Andersen, Finn Husøy; Artigas, Antonio; Cecconi, Maurizio; Boumendil, Ariane; Elhadi, Muhammed; Fjølner, Jesper; Joannidis, Michael; Jung, Christian; Leaver, Susannah; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Nalapko, Yuriy; Schefold, Joerg C.; Szczeklik, Wojciech; Walther, Sten; Watson, Ximena; Zafeiridis, Tilemachos; de Lange, Dylan W. (Journal article; Peer reviewed, 2021)
      Purpose Frailty is a valuable predictor for outcome in elderly ICU patients, and has been suggested to be used in various decision-making processes prior to and during an ICU admission. There are many instruments developed ...
    • Sepsis at ICU admission does not decrease 30-day survival in very old patients: a post-hoc analysis of the VIP1 multinational cohort study 

      Ibarz, Mercedes; Boumendil, Ariane; Flaatten, Hans; Andersen, Finn Husøy; Artigas, Antonio; Haas, Lenneke E. M.; Irazabal, Marian; de Lange, Dylan W.; Morandi, Alessandro; Bertolini, Guido; Cecconi, Maurizio; Christensen, Stefen; Faraldi, Loredana; Fjølner, Jesper; Jung, Christian; Marsh, Brian; Moreno, Rui; Oeyen, Sandra; Öhman, Christina Agwald; Pinto, Bernardo Bollen; Soliman, Ivo W.; Valentin, Andreas; Szczeklik, Wojciech; Watson, Ximena; Zaferidis, Tilemachos; Guidet, Bertrand; Artigas, Antonio (Journal article; Peer reviewed, 2020)
      Background The number of intensive care patients aged ≥ 80 years (Very old Intensive Care Patients; VIPs) is growing. VIPs have high mortality and morbidity and the benefits of ICU admission are frequently questioned. ...