• Association of chronic heart failure with mortality in old intensive care patients suffering from Covid-19 

      Bruno, Raphael Romano; Wernly, Bernhard; Wolff, Georg; Fjølner, Jesper; Artigas, Antonio; Bollen Pinto, Bernardo; Schefold, Joerg C.; Kindgen-Milles, Detlef; Baldia, Philipp Heinrich; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Topeli, Arzu; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Kondili, Eumorfia; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian; Jung, Christian (Journal article; Peer reviewed, 2022)
      Aims Chronic heart failure (CHF) is a major risk factor for mortality in coronavirus disease 2019 (COVID-19). This prospective international multicentre study investigates the role of pre-existing CHF on clinical outcomes ...
    • Differences in mortality in critically ill elderly patients during the second COVID‑19 surge in Europe 

      Jung, Christian; Fjølner, Jesper; Bruno, Raphael Romano; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolf, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Czuczwar, Miroslaw; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Andersen, Finn H.; Moreno, Rui; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans (Journal article; Peer reviewed, 2021)
      Background: The primary aim of this study was to assess the outcome of elderly intensive care unit (ICU) patients treated during the spring and autumn COVID-19 surges in Europe. Methods: This was a prospective European ...
    • The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study 

      Jung, Christian; Flaatten, Hans; Fjølner, Jesper; Romano Bruno, Raphael; Wernly, Bernhard; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sviri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Czuczwar, Miroslaw; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand (Journal article; Peer reviewed, 2021)
      Background The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in ...
    • Lactate is associated with mortality in very old intensive care patients suffering from COVID-19: results from an international observational study of 2860 patients 

      Bruno, Raphael Romano; Wernley, Bernhard; Flaatten, Hans; Fjølner, Jesper; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Binnebössel, Stephan; Baldia, Philipp Heinrich; Kelm, Malte; Beil, Michael; Sigal, Sivri; van Heerden, Peter Vernon; Szczeklik, Wojciech; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Wollborn, Jakob; Banzo, Maria José Arche; Fuest, Kristina; Marsh, Brian; Andersen, Finn H.; Moreno, Rui; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Jung, Christian (Journal article; Peer reviewed, 2021)
      Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have ...
    • A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems 

      Wernly, Bernhard; Flaatten, Hans Kristian; Beil, Michael; Fjølner, Jesper; Bruno, Raphael Romano; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Kelm, Malte; Sigal, Sviri; van Heerden, Peter Vernon; Szczeklik, Wojciech; Elhadi, Muhammed; Joannidis, Michael; Rezar, Richard; Oeyen, Sandra; Wolff, Georg; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Wernly, Sarah; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Perings, Stefan; Jung, Christian (Journal article; Peer reviewed, 2022)
      In Europe, tax-based healthcare systems (THS) and social health insurance systems (SHI) coexist. We examined differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in intensive care units in ...
    • Sex-specific treatment characteristics and 30-day mortality outcomes of critically ill COVID-19 patients over 70 years of age—results from the prospective COVIP study 

      Wolff, Georg; Wernly, Bernhard; Flaatten, Hans Kristian; Fjølner, Jesper; Bruno, Raphael Romano; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Joerg C.; Kelm, Malte; Binneboessel, Stephan; Baldia, Philipp; Beil, Michael; Sivri, Sigal; van Heerden, Peter Vernon; Szczeklik, Wojciech; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Flamm, Maria; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Leaver, Susannah; Jung, Christian (Journal article; Peer reviewed, 2022)
      Purpose Older critically ill patients with COVID-19 have been the most vulnerable during the ongoing pandemic, with men being more prone to hospitalization and severe disease than women. We aimed to explore sex-specific ...
    • Steroid use in elderly critically ill COVID-19 patients 

      Jung, Christian; Wernly, Bernhard; Fjølner, Jesper; Bruno, Raphael Romano; Dudzinski, David; Artigas, Antonio; Pinto, Bernardo Bollen; Schefold, Jörg C.; Wolff, Georg; Kelm, Malte; Beil, Michael; Sigal, Sviri; van Heerden, Peter Vernon; Szczeklik, Wojciech; Czuczwar, Mirosław; Elhadi, Muhammed; Joannidis, Michael; Oeyen, Sandra; Zafeiridis, Tilemachos; Marsh, Brian; Andersen, Finn Husøy; Moreno, Rui; Cecconi, Maurizio; Leaver, Susannah; Boumendil, Ariane; De Lange, Dylan W.; Guidet, Bertrand; Flaatten, Hans Kristian (Journal article; Peer reviewed, 2021)
      This secondary analysis of the COVIP study shows a higher 30-day mortality in critically ill elderly COVID-19 patients who received steroids as part of their treatment