Browsing Registrations from Cristin by Title
Now showing items 9094-9113 of 11244
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S100A4 mRNA-protein relationship uncovered by measurement noise reduction
(Journal article; Peer reviewed, 2020)Intrinsic biological fluctuation and/or measurement error can obscure the association of gene expression patterns between RNA and protein levels. Appropriate normalization of reverse-transcription quantitative PCR (RT-qPCR) ... -
S3-inspired three-Higgs-doublet models: A class with a complex vacuum
(Journal article; Peer reviewed, 2020)In this paper we analyze in detail an S3-symmetric three-Higgs-doublet model with a specific vacuum configuration. This analysis allows us to illustrate important features of models with several Higgs doublets, such as the ... -
A Saddle-Shaped Expanded Porphyrinoid Fitting C60**
(Journal article; Peer reviewed, 2023)We present the synthesis of a new type of an expanded porphyrinoid macrocycle with a saddle-shaped morphology and its complexation of C60 guest molecules. The new macrocycle contains four carbazole and four triazole moieties ... -
SAF-A/hnRNP U binds polyphosphoinositides via a lysine rich polybasic motif located in the SAP domain
(Journal article; Peer reviewed, 2023)Polyphosphoinositides (PPIn) play essential functions as lipid signalling molecules and many of their functions have been elucidated in the cytoplasm. However, PPIn are also intranuclear where they contribute to chromatin ... -
A safe and effective micro-choice based rehabilitation for patients with long COVID: results from a quasi-experimental study
(Journal article; Peer reviewed, 2023)At least 65 million people suffer from long COVID. Treatment guidelines are unclear, especially pertaining to recommendations of increased activity. This longitudinal study evaluated safety, changes in functional level and ... -
Safety and Clinical Efficacy of Mesenchymal Stem Cell Treatment in Traumatic Spinal Cord Injury, Multiple Sclerosis and Ischemic Stroke – A Systematic Review and Meta-Analysis
(Journal article; Peer reviewed, 2022-05-30)Background: Mesenchymal stem cells (MSCs) is an attractive candidate in regenerative research and clinical trials have assessed their therapeutic potential in different neurological conditions with disparate etiologies. ... -
Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation
(Journal article; Peer reviewed, 2012)Purpose: To evaluate the efficacy and safety of epithelium-on corneal collagen cross-linking (CXL) using a multifactorial approach to achieve proper stromal riboflavin saturation. Methods: This non-randomized retrospective ... -
Safety and efficacy of faecal microbiota transplantation by Anaerobic Cultivated Human Intestinal Microbiome (ACHIM) in patients with systemic sclerosis: Study protocol for the randomised controlled phase II ReSScue trial
(Journal article; Peer reviewed, 2021)Introduction: In the multisystem inflammatory disorder systemic sclerosis (SSc), gastrointestinal tract (GIT) affliction is highly prevalent. There are no known disease modifying therapies and the negative impact is ... -
Safety and efficacy of pegunigalsidase alfa in patients with Fabry disease who were previously treated with agalsidase alfa: results from BRIDGE, a phase 3 open-label study
(Journal article; Peer reviewed, 2023)Background Pegunigalsidase alfa is a novel, PEGylated α-galactosidase-A enzyme-replacement therapy approved in the EU and US to treat patients with Fabry disease (FD). Objective/methods BRIDGE is a phase 3 open-label, ... -
Safety and efficacy of rituximab as first- and second line treatment in multiple sclerosis – A cohort study
(Journal article; Peer reviewed, 2021-01-31)Background Rituximab is increasingly used as off-label therapy in multiple sclerosis (MS). More data are needed on safety and efficacy of rituximab, particularly in cohorts of de novo patients and patients in early therapy ... -
Safety and pharmacokinetics of subcutaneous administration of broadly neutralizing anti-HIV-1 monoclonal antibodies (bNAbs), given to HIV-1 exposed, uninfected neonates and infants: study protocol for a phase I trial
(Journal article; Peer reviewed, 2024)Background The ambitious goal to eliminate new pediatric HIV infections by 2030 requires accelerated prevention strategies in high-risk settings such as South Africa. One approach could be pre-exposure prophylaxis (PrEP) ... -
Safety and Reverence: How Roman Catholic Liturgy Can Respond to the COVID-19 Pandemic
(Journal article; Peer reviewed, 2021)The current COVID-19 pandemic is a major challenge for many religious denominations. The Roman Catholic Church strongly depends on physical communal worship and sacraments. Disagreements grow concerning the best balance ... -
Safety assessment of the functional feed additive phenylcapsaicin in a commercial broiler diet
(Journal article; Peer reviewed, 2023)Introduction: Intestinal colonisation of Salmonella is a major concern in the poultry industry, and a low dose of the high-purity synthetic capsaicin analogue phenylcapsaicin (PheCap) has the potential to be a phytobiotic ... -
Safety of breast feeding during rituximab treatment in multiple sclerosis
(Journal article; Peer reviewed, 2022)Background There are limited data on the safety of breast feeding during rituximab therapy. Our objective is to determine exposure from breast feeding and biological effects of rituximab in breastfed infants. Methods ... -
Safety of drug use in patients with a primary mitochondrial disease: An international Delphi-based consensus
(Journal article; Peer reviewed, 2020)Clinical guidance is often sought when prescribing drugs for patients with primary mitochondrial disease. Theoretical considerations concerning drug safety in patients with mitochondrial disease may lead to unnecessary ... -
Safety of hypoxic red blood cell administration in patients with transfusion-dependent hematological malignancies: An interim analysis
(Journal article; Peer reviewed, 2023)Anemia is a common symptom of hematological malignancies and red blood cell (RBC) transfusion is the primary supportive treatment, with many patients becoming transfusion dependent. Hemanext Inc. (Lexington, MA, United ... -
Safety profile of herbal medicines submitted for marketing authorization in Tanzania: a cross-sectional retrospective study
(Journal article; Peer reviewed, 2023)Background The popular use of herbal medicines necessitates national regulatory authorities to have efficient mechanisms for the control of these products including marketing authorization (MA) and safety follow-up. ... -
Safety, Immunogenicity, Efficacy and Effectiveness of Inactivated Influenza Vaccines in Healthy Pregnant Women and Children Under 5 Years: An Evidence-Based Clinical Review
(Journal article; Peer reviewed, 2021)Annual influenza vaccination is often recommended for pregnant women and young children to reduce the risk of severe influenza. However, most studies investigating the safety, immunogenicity, and efficacy or effectiveness ... -
The Saliva and Muscle Study (SaMu): Rationale and Protocol for Associations between Salivary Microbiome and Accelerated Muscle Ageing
(Journal article; Peer reviewed, 2024)Background The gut microbiome is recognized as a pivotal factor in the pathophysiology of sarcopenia—a condition marked by the accelerated loss of muscle strength, mass and function with ageing. Despite this well-known ... -
Salivary Gland Ultrasonography in Sjögren’s Syndrome: A European Multicenter Reliability Exercise for the HarmonicSS Project
(Journal article, 2020)Objectives: Salivary gland ultrasonography (SGUS) is increasingly applied for the management of primary Sjögren's syndrome (pSS). This study aims to: (i) compare the reliability between two SGUS scores; (ii) test the ...