• Design efficiency in genetic association studies 

      Gjerdevik, Miriam; Gjessing, Håkon K.; Romanowska, Julia; Haaland, Øystein Ariansen; Jugessur, Astanand; Czajkowski, Nikolai Olavi; Lie, Rolv T. (Journal article; Peer reviewed, 2020)
      Selecting the best design for genetic association studies requires careful deliberation; different study designs can be used to scan for different genetic effects, and each design has its own set of strengths and limitations. ...
    • Estimating health adjusted age at death (HAAD) 

      Johansson, Kjell Arne; Økland, Jan-Magnus; Skaftun, Eirin Krüger; Bukhman, Gene; Norheim, Ole Frithjof; Coates, Matthew M.; Haaland, Øystein Ariansen (Journal article; Peer reviewed, 2020-07-14)
      Objectives: At any point in time, a person’s lifetime health is the number of healthy life years they are expected to experience during their lifetime. In this article we propose an equity-relevant health metric, Health ...
    • Frailty and survival in elderly intensive care patients in Norway 

      Andersen, Finn Husøy; Haaland, Øystein Ariansen; Klepstad, Pål; Flaatten, Hans (Journal article; Peer reviewed, 2021)
      Background Today, 10%-15% of Norwegian intensive care patients are ≥80 years. This proportion will increase significantly over the next 20 years, but it is unlikely that resources for intensive care increase correspondingly. ...
    • Gene-methylation interactions: Discovering region-wise DNA methylation levels that modify SNP-associated disease risk 

      Romanowska, Julia; Haaland, Øystein Ariansen; Jugessur, Astanand; Gjerdevik, Miriam; Xu, Zongli; Taylor, Jack A.; Wilcox, Allen J; Jonassen, Inge; Lie, Rolv T.; Gjessing, Håkon K. (Journal article; Peer reviewed, 2020)
      Background Current technology allows rapid assessment of DNA sequences and methylation levels at a single-site resolution for hundreds of thousands of sites in the human genome, in thousands of individuals simultaneously. ...
    • Maternal use of folic acid and multivitamin supplements and infant risk of birth defects in Norway, 1999–2013 

      Gildestad, Trude; Bjørge, Tone; Haaland, Øystein Ariansen; Klungsøyr, Kari; Vollset, Stein Emil; Øyen, Nina (Journal article; Peer reviewed, 2020)
      The association between folic acid supplementation and birth defects other than neural tube defects (NTD) remains unclear. We used a log-binomial regression model to investigate if periconceptional folic acid and/or ...
    • Protecting essential health services in low-income and middle-income countries and humanitarian settings while responding to the COVID-19 pandemic 

      Blanchet, Karl; Alwan, Ala; Antoine, Caroline; Cros, Marion Jane; Feroz, Ferozuddin; Amsalu Guracha, Tseguaneh; Haaland, Øystein Ariansen; Hailu, Alemayehu; Hangoma, Peter; Jamison, Dean T.; Memirie, Solomon Tessema; Miljeteig, Ingrid; Jan Naeem, Ahmad; Nam, Sara L.; Norheim, Ole Frithjof; Verguet, Stéphane; Watkins, David; Johansson, Kjell Arne (Journal article; Peer reviewed, 2020)
      In health outcomes terms, the poorest countries stand to lose the most from these disruptions. In this paper, we make the case for a rational approach to public sector health spending and decision making during and in the ...
    • Wavelet Screening identifies regions highly enriched for differentially methylated loci for orofacial clefts 

      Denault, William Robert Paul; Romanowska, Julia; Haaland, Øystein Ariansen; Lyle, Robert; Taylor, Jack A.; Xu, Zongli; Lie, Rolv T.; Gjessing, Håkon K.; Jugessur, Astanand (Journal article; Peer reviewed, 2021)
      DNA methylation is the most widely studied epigenetic mark in humans and plays an essential role in normal biological processes as well as in disease development. More focus has recently been placed on understanding ...