• Affect Recognition in Muscular Response Signals 

      Boeker, Matthias; Jakobsen, Petter; Riegler, Michael; Stabell, Lena Antonsen; Fasmer, Ole Bernt; Halvorsen, Pål; Hammer, Hugo Lewi (Journal article; Peer reviewed, 2023)
      This study investigated the potential of recognising arousal in motor activity collected by wrist-worn accelerometers. We hypothesise that emotional arousal emerges from the generalised central nervous system which embeds ...
    • Applying machine learning in motor activity time series of depressed bipolar and unipolar patients compared to healthy controls 

      Jakobsen, Petter; Garcia-Ceja, Enrique; Riegler, Michael; Stabell, Lena Antonsen; Nordgreen, Tine; Tørresen, Jim; Fasmer, Ole Bernt; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2020)
      Current practice of assessing mood episodes in affective disorders largely depends on subjective observations combined with semi-structured clinical rating scales. Motor activity is an objective observation of the inner ...
    • The association between lithium use and neurocognitive performance in patients with bipolar disorder 

      Burdick, Katherine E.; Millett, Caitlin E.; Russo, Manuela; Alda, Martin; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; DeModena, Anna; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Glazer, Kara; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Løberg, Else-Marie; Lohoff, Falk W.; Maihofer, Adam X.; McCarthy, Michael J.; McInnis, Melvin; Morken, Gunnar; Nievergelt, Caroline M.; Nurnberger, John I.; Oedegaard, Ketil J.; Ortiz, Abigail; Ritchey, Megan; Ryan, Kelly; Schinagle, Martha; Schwebel, Candice; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma; Tarwater, Bruce; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2020)
      Lithium remains the gold standard for the treatment of bipolar disorder (BD); however, its use has declined over the years mainly due to the side effects and the subjective experience of cognitive numbness reported by ...
    • Challenges and possible solutions in cross-disciplinary and cross-sectorial research teams within the domain of e-mental health 

      Nordgreen, Tine; Rabbi, Fazle; Tørresen, Jim; Skar, Yngvar Sigmund; Guribye, Frode; Inal, Yavuz; Flobak, Eivind; Wake, Jo Dugstad; Mukhiya, Suresh Kumar; Aminifar, Amin; Myklebost, Sunniva Brurok; Lundervold, Astri J.; Kenter, Robin Maria Francisca; Hammar, Åsa Karin; Kahlon, Smiti; Nordby, Emilie; Sekse, Ragnhild Johanne Tveit; Griffin, Kristine Fonnes; Jakobsen, Petter; Pham, Hoang Minh; Côté-Allard, Ulysse Teller Masao; Noori, Farzan Majeed; Lamo, Yngve (Journal article; Peer reviewed, 2021)
      Purpose: Mental illness presents a huge individual, societal and economic challenges, currently accounting for 20% of the worldwide burden of disease. There is a gap between the need for and access to services. Digital ...
    • Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study 

      Lin, Yan; Maihofer, Adam X.; Stapp, Emma; Ritchey, Megan; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H; Bertram, Holli; Bhattacharjee, Abesh; Calkin, Cynthia V.; Conroy, Carla; Coryell, William; D´Arcangelo, Nicole; DeModena, Anna; Biernacka, Joanna M.; Fisher, Carrie; Frazier, Nicole; Frye, Mark; Gao, Keming; Garnham, Julie; Gershon, Elliot; Glazer, Kara; Goes, Fernando S; Goto, Toyomi; Karberg, Elizabeth; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; Stautland, Andrea; McCarthy, Michael J.; McInnis, Melvin G.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Ødegaard, Ketil Joachim; Syrstad, Vigdis Elin Giæver; Ryan, Kelly; Schinagle, Martha; Schøyen, Helle Kristine; Andreassen, Ole; Shaw, Martha; Shilling, Paul D.; Slaney, Claire; Tarwater, Bruce; Calabrese, Joseph R.; Alda, Martin; Nievergelt, Caroline M.; Zandi, Peter P.; Kelsoe, John R. (Journal article; Peer reviewed, 2021)
      Background Lithium is regarded as a first-line treatment for bipolar disorder (BD), but partial response and non-response commonly occurs. There exists a need to identify lithium non-responders prior to initiating treatment. ...
    • Complexity and variability analyses of motor activity distinguish mood states in Bipolar Disorder 

      Jakobsen, Petter; Stautland, Andrea; Riegler, Michael; Côté-Allard, Ulysse Teller Masao; Sepasdar, Zahra; Nordgreen, Tine; Tørresen, Jim; Fasmer, Ole Bernt; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2022)
      Changes in motor activity are core symptoms of mood episodes in bipolar disorder. The manic state is characterized by increased variance, augmented complexity and irregular circadian rhythmicity when compared to healthy ...
    • Diagnosing Schizophrenia from Activity Records using Hidden Markov Model Parameters 

      Boeker, Matthias; Riegler, Michael; Hammer, Hugo Lewi; Halvorsen, Pål; Fasmer, Ole Bernt; Jakobsen, Petter (Chapter, 2021)
      The diagnosis of Schizophrenia is mainly based on qualitative characteristics. With the usage of portable devices which measure activity of humans, the diagnosis of Schizophrenia can be enriched through quantitative features. ...
    • Diurnal variation of motor activity in adult ADHD patients analyzed with methods from graph theory 

      Fasmer, Ole Bernt; Fasmer, Erlend Eindride; Mjeldheim, Kristin; Førland, Wenche; Syrstad, Vigdis Elin Giæver; Jakobsen, Petter; Berle, Jan Øystein; Henriksen, Tone Elise Gjøtterud; Sepasdar, Zahra; Hauge, Erik Rønneberg; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2020-11)
      Attention-deficit /hyperactivity disorder (ADHD) is a common neurodevelopmental syndrome characterized by age-inappropriate levels of motor activity, impulsivity and attention. The aim of the present study was to study ...
    • Focal adhesion is associated with lithium response in bipolar disorder: evidence from a network-based multi-omics analysis 

      Niemsiri, Vipavee; Rosenthal, Sara Brin; Nievergelt, Caroline M.; Maihofer, Adam X.; Marchetto, Maria C.; Santos, Renata; Shekhtman, Tatyana; Alliey-Rodriguez, Ney; Anand, Amit; Balaraman, Yokesh; Berrettini, Wade H.; Bertram, Holli; Burdick, Katherine E.; Calabrese, Joseph R.; Calkin, Cynthia V.; Conroy, Carla; Coryell, William H.; DeModena, Anna; Eyler, Lisa T.; Feeder, Scott; Fisher, Carrie; Frazier, Nicole; Frye, Mark A.; Gao, Keming; Garnham, Julie; Gershon, Elliot S.; Goes, Fernando S.; Goto, Toyomi; Harrington, Gloria J.; Jakobsen, Petter; Kamali, Masoud; Kelly, Marisa; Leckband, Susan G.; Lohoff, Falk W.; McCarthy, Michael J.; McInnis, Melvin G.; Craig, David; Millett, Caitlin E.; Mondimore, Francis; Morken, Gunnar; Nurnberger, John I.; Donovan, Claire O’; Ødegaard, Ketil Joachim; Ryan, Kelly; Schinagle, Martha; Shilling, Paul D.; Slaney, Claire; Stapp, Emma K.; Stautland, Andrea; Tarwater, Bruce; Zandi, Peter P.; Alda, Martin; Fisch, Kathleen M.; Gage, Fred H.; Kelsoe, John R. (Journal article; Peer reviewed, 2023)
      Lithium (Li) is one of the most effective drugs for treating bipolar disorder (BD), however, there is presently no way to predict response to guide treatment. The aim of this study is to identify functional genes and ...
    • HYPERAKTIV: An Activity Dataset from Patients with Attention-Deficit/Hyperactivity Disorder (ADHD) 

      Hicks, Steven; Stautland, Andrea; Fasmer, Ole Bernt; Førland, Wenche; Hammer, Hugo Lewi; Halvorsen, Pål; Mjeldheim, Kristin; Ødegaard, Ketil Joachim; Osnes, Berge; Syrstad, Vigdis Elin Giæver; Riegler, Michael; Jakobsen, Petter (Chapter, 2021)
      Machine learning research within healthcare frequently lacks the public data needed to be fully reproducible and comparable. Datasets are often restricted due to privacy concerns and legal requirements that come with ...
    • Objective assessment of motor activity in a clinical sample of adults with attention-deficit/hyperactivity disorder and/or cyclothymic temperament 

      Syrstad, Vigdis Elin Giæver; Mjeldheim, Kristin; Førland, Wenche; Jakobsen, Petter; Gjestad, Rolf; Berle, Jan Øystein; Merikangas, Kathleen Ries; Ødegaard, Ketil Joachim; Fasmer, Ole Bernt (Journal article; Peer reviewed, 2022)
      Background Most research on patterns of motor activity has been conducted on adults with mood disorders, but few studies have investigated comorbid attention-deficit/hyperactivity disorder (ADHD) or temperamental factors ...
    • Reduced heart rate variability during mania in a repeated naturalistic observational study 

      Stautland, Andrea; Jakobsen, Petter; Fasmer, Ole Bernt; Osnes, Berge; Tørresen, Jim; Nordgreen, Tine; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2023)
      Background: Bipolar disorder (BD) is a chronic recurrent mood disorder associated with autonomic nervous system (ANS) dysfunction, indexed by heart rate variability (HRV). Changes in HRV between mood states are sparsely ...
    • Towards Adaptive Technology in Routine Mental Healthcare 

      Lamo, Yngve; Mukhiya, Suresh Kumar; Rabbi, Fazle; Aminifar, Amin; Lillehaug, Svein Ivar; Tørresen, Jim; Pham, Minh H.; Côté-Allard, Ulysse Teller Masao; Noori, Farzan Majeed; Guribye, Frode; Inal, Yavuz; Flobak, Eivind; Wake, Jo Dugstad; Myklebost, Sunniva Brurok; Lundervold, Astri J.; Hammar, Åsa Karin; Nordby, Emilie Sektnan; Kahlon, Smiti; Kenter, Robin Maria Francisca; Sekse, Ragnhild Johanne Tveit; Griffin, Kristine Fonnes; Jakobsen, Petter; Ødegaard, Ketil Joachim; Skar, Yngvar Sigmund; Nordgreen, Tine (Journal article; Peer reviewed, 2022)
      This paper summarizes the information technology-related research findings after 5 years with the INTROducing Mental health through Adaptive Technology project. The aim was to improve mental healthcare by introducing new ...