dc.contributor.author | Grønning, Kaja | |
dc.contributor.author | Sharma, Archana | |
dc.contributor.author | Mastroianni, Maria Adele | |
dc.contributor.author | Karlsson, Bo Daniel | |
dc.contributor.author | Husebye, Eystein Sverre | |
dc.contributor.author | Løvås, Kristian | |
dc.contributor.author | Nermoen, Ingrid | |
dc.date.accessioned | 2021-04-20T10:22:58Z | |
dc.date.available | 2021-04-20T10:22:58Z | |
dc.date.created | 2020-11-16T14:02:49Z | |
dc.date.issued | 2020-03 | |
dc.Published | Endocrinology, Diabetes & Metabolism. 2020, 2020 (1), 1-5. | en_US |
dc.identifier.issn | 2398-9238 | |
dc.identifier.uri | https://hdl.handle.net/11250/2738608 | |
dc.description.abstract | Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency. More than 90% is of B-cell origin. The condition is bilateral in up to 75% of cases, with adrenal insufficiency in two of three patients. We report two cases of adrenal insufficiency presenting at the age of 70 and 79 years, respectively. Both patients had negative 21-hydroxylase antibodies with bilateral adrenal lesions on CT. Biopsy showed B-cell lymphoma. One of the patients experienced intermittent disease regression on replacement dosage of glucocorticoids.
Learning points:
Primary adrenal lymphoma (PAL) is a rare cause of adrenal insufficiency.
Bilateral adrenal masses of unknown origin or in individuals with suspected extra-adrenal malignancy should be biopsied quickly when pheochromocytoma is excluded biochemically.
Steroid treatment before biopsy may affect diagnosis.
Adrenal insufficiency with negative 21-hydroxylase antibodies should be evaluated radiologically. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Bioscientifica | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Primary adrenal lymphoma as a cause of adrenal insufficiency, a report of two cases | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright the authors | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.1530/EDM-19-0131 | |
dc.identifier.cristin | 1848369 | |
dc.source.journal | Endocrinology, Diabetes & Metabolism | en_US |
dc.source.40 | 2020 | en_US |
dc.source.14 | 1 | en_US |
dc.source.pagenumber | 1-5 | en_US |
dc.identifier.citation | Endocrinology, Diabetes & Metabolism. 2020, 2020 (1), 19-0131. | |