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dc.contributor.authorAlexander, Jan
dc.contributor.authorTinkov, Alexey A.
dc.contributor.authorStrand, Tor A
dc.contributor.authorAlehagen, Urban
dc.contributor.authorSkalny, Anatoly V.
dc.contributor.authorAaseth, Jan
dc.date.accessioned2021-06-21T09:21:34Z
dc.date.available2021-06-21T09:21:34Z
dc.date.created2020-10-05T12:51:18Z
dc.date.issued2020
dc.identifier.issn2072-6643
dc.identifier.urihttps://hdl.handle.net/11250/2760357
dc.description.abstractObjectives: The novel coronavirus infection (COVID-19) conveys a serious threat globally to health and economy because of a lack of vaccines and specific treatments. A common factor for conditions that predispose for serious progress is a low-grade inflammation, e.g., as seen in metabolic syndrome, diabetes, and heart failure, to which micronutrient deficiencies may contribute. The aim of the present article was to explore the usefulness of early micronutrient intervention, with focus on zinc, selenium, and vitamin D, to relieve escalation of COVID-19. Methods: We conducted an online search for articles published in the period 2010–2020 on zinc, selenium, and vitamin D, and corona and related virus infections. Results: There were a few studies providing direct evidence on associations between zinc, selenium, and vitamin D, and COVID-19. Adequate supply of zinc, selenium, and vitamin D is essential for resistance to other viral infections, immune function, and reduced inflammation. Hence, it is suggested that nutrition intervention securing an adequate status might protect against the novel coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome - coronavirus-2) and mitigate the course of COVID-19. Conclusion: We recommended initiation of adequate supplementation in high-risk areas and/or soon after the time of suspected infection with SARS-CoV-2. Subjects in high-risk groups should have high priority as regards this nutritive adjuvant therapy, which should be started prior to administration of specific and supportive medical measures.en_US
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.urihttps://www.mdpi.com/2072-6643/12/8/2358/htm
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleEarly Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19en_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2020 by the authors.en_US
dc.source.articlenumber2358en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.3390/nu12082358
dc.identifier.cristin1837074
dc.source.journalNutrientsen_US
dc.identifier.citationNutrients. 2020, 12 (8), 2358.en_US
dc.source.volume12en_US
dc.source.issue8en_US


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