Vis enkel innførsel

dc.contributor.authorLi, Lin
dc.contributor.authorTaylor, Mark J.
dc.contributor.authorBälter, Katarina
dc.contributor.authorKuja-Halkola, Ralf
dc.contributor.authorChen, Qi
dc.contributor.authorHegvik, Tor-Arne
dc.contributor.authorTate, Ashley E.
dc.contributor.authorChang, Zheng
dc.contributor.authorArias-Vasquez, Alejandro
dc.contributor.authorHartman, Catharina A.
dc.contributor.authorLarsson, Henrik
dc.date.accessioned2021-08-05T09:21:50Z
dc.date.available2021-08-05T09:21:50Z
dc.date.created2021-01-05T12:10:43Z
dc.date.issued2020
dc.identifier.issn1552-4841
dc.identifier.urihttps://hdl.handle.net/11250/2766403
dc.description.abstractAssociations between adult attention-deficit/hyperactivity disorder (ADHD) symptoms and dietary habits have not been well established and the underlying mechanisms remain unclear. We explored these associations using a Swedish population-based twin study with 17,999 individuals aged 20–47 years. We estimated correlations between inattention and hyperactivity/impulsivity with dietary habits and fitted twin models to determine the genetic and environmental contributions. Dietary habits were defined as (a) consumption of food groups, (b) consumption of food items rich in particular macronutrients, and (c) healthy and unhealthy dietary patterns. At the phenotypic level, inattention was positively correlated with seafood, high-fat, high-sugar, high-protein food consumptions, and unhealthy dietary pattern, with correlation coefficients ranging from 0.03 (95%CI: 0.01, 0.05) to 0.13 (95% CI: 0.11, 0.15). Inattention was negatively correlated with fruits, vegetables consumptions and healthy dietary pattern, with correlation coefficients ranging from −0.06 (95%CI: −0.08, −0.04) to −0.07 (95%CI: −0.09, −0.05). Hyperactivity/impulsivity and dietary habits showed similar but weaker patterns compared to inattention. All associations remained stable across age, sex and socioeconomic status. Nonshared environmental effects contributed substantially to the correlations of inattention (56–60%) and hyperactivity/impulsivity (63–80%) with dietary habits. The highest and lowest genetic correlations were between inattention and high-sugar food (rA = .16, 95% CI: 0.07, 0.25), and between hyperactivity/impulsivity and unhealthy dietary pattern (rA = .05, 95% CI: −0.05, 0.14), respectively. We found phenotypic and etiological overlap between ADHD and dietary habits, although these associations were weak. Our findings contribute to a better understanding of common etiological pathways between ADHD symptoms and various dietary habits.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleAttention-deficit/hyperactivity disorder symptoms and dietary habits in adulthood: A large population-based twin study in Swedenen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2020 The Authorsen_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.1002/ajmg.b.32825
dc.identifier.cristin1865467
dc.source.journalAmerican Journal of Medical Genetics Part B: Neuropsychiatric Geneticsen_US
dc.source.pagenumber475-485en_US
dc.relation.projectEC/H2020/728018en_US
dc.identifier.citationAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2020, 183 (8), 475-485.en_US
dc.source.volume183en_US
dc.source.issue8en_US


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel

Navngivelse 4.0 Internasjonal
Med mindre annet er angitt, så er denne innførselen lisensiert som Navngivelse 4.0 Internasjonal