Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies
dc.contributor.author | Hansen, Kim Wadt | |
dc.contributor.author | Peytz, Nina | |
dc.contributor.author | Blokstra, Anneke | |
dc.contributor.author | Bojesen, Stig E. | |
dc.contributor.author | Celis-Morales, Carlos | |
dc.contributor.author | Chrysohoou, Christina | |
dc.contributor.author | Clays, Els | |
dc.contributor.author | De Bacquer, Dirk | |
dc.contributor.author | Galatius, Søren | |
dc.contributor.author | Gray, Stuart R. | |
dc.contributor.author | Ho, Frederick | |
dc.contributor.author | Kavousi, Maryam | |
dc.contributor.author | Koolhaas, Chantal M. | |
dc.contributor.author | Kouvari, Matina | |
dc.contributor.author | Løchen, Maja-Lisa | |
dc.contributor.author | Marques-Vidal, Pedro | |
dc.contributor.author | Osler, Merete | |
dc.contributor.author | Panagiotakos, Demosthenes | |
dc.contributor.author | Pell, Jill P. | |
dc.contributor.author | Sulo, Gerhard | |
dc.contributor.author | Tell, Grethe Seppola | |
dc.contributor.author | Vassiliou, Vassilios | |
dc.contributor.author | Verschuren, W.M. Monique | |
dc.contributor.author | Prescott, Eva | |
dc.date.accessioned | 2021-08-10T14:35:19Z | |
dc.date.available | 2021-08-10T14:35:19Z | |
dc.date.created | 2021-04-22T12:49:09Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 2047-4873 | |
dc.identifier.uri | https://hdl.handle.net/11250/2767232 | |
dc.description.abstract | Aims To assess the association between past level of physical activity (PA) and risk for death during the acute phase of myocardial infarction (MI) in a pooled analysis of cohort studies. Methods and results European cohorts including participants with a baseline assessment of PA, conventional cardiovascular (CV) risk factors, and available follow-up on MI and death were eligible. Patients with an incident MI were included. Leisure-time PA was grouped as sedentary (<7 MET-hours), low (7–16 MET-hours), moderate (16.1–32 MET-hours), or high (>32 MET-hours) based on calculated net weekly energy expenditure. The main outcome measures were instant and 28-day case fatality of MI. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using multivariate random-effects models. Adjustments for age, sex, CV risk factors, alcohol consumption, and socioeconomic status were made. From 10 cohorts including a total of 1 495 254 participants, 28 140 patients with an incident MI comprised the study population. A total of 4976 (17.7%) died within 28 days—of these 3101 (62.3%) were classified as instant fatal MI. Compared with sedentary individuals, those with a higher level of PA had lower adjusted odds of instant fatal MI: low PA [OR, 0.79 (95% CI, 0.60–1.04)], moderate PA [0.67 (0.51–0.89)], and high PA [0.55 (0.40–0.76)]. Similar results were found for 28-day fatal MI: low PA [0.85 (0.71–1.03)], moderate PA [0.64 (0.51–0.80)], and high PA [0.72 (0.51–1.00)]. A low-to-moderate degree of heterogeneity was detected in the analysis of instant fatal MI (I2 = 47.3%), but not in that of 28-day fatal MI (I2 = 0.0%). Conclusion A moderate-to-high level of PA was associated with a lower risk of instant and 28-day death in relation to a MI. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Oxford University Press | en_US |
dc.title | Association of fatal myocardial infarction with past level of physical activity: a pooled analysis of cohort studies | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | acceptedVersion | en_US |
dc.rights.holder | Copyright The Author(s) 2021. Published on behalf of the European Society of Cardiology. All rights reserved. | en_US |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.qualitycode | 2 | |
dc.identifier.doi | 10.1093/eurjpc/zwaa146 | |
dc.identifier.cristin | 1905845 | |
dc.source.journal | European Journal of Preventive Cardiology (EJPC) | en_US |
dc.source.pagenumber | 1590–1598 | |
dc.identifier.citation | European Journal of Preventive Cardiology (EJPC). 2021, 28 (14), 1590–1598. | en_US |
dc.source.volume | 28 | |
dc.source.issue | 14 |