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dc.contributor.authorHov, Brit
dc.contributor.authorAndersen, Tiina Maarit
dc.contributor.authorToussaint, Michel
dc.contributor.authorVollsæter, Maria
dc.contributor.authorMikalsen, Ingvild Bruun
dc.contributor.authorIndrekvam, Solfrid
dc.contributor.authorHovland, Vegard
dc.description.abstractAim: To determine the prevalence of long-term mechanical insufflation-exsufflation (MI-E) and concomitant mechanical ventilation in children with neurological conditions, with reported reasons behind the initiation of treatment. Method: This was a population-based, cross-sectional study using Norwegian national registries and a questionnaire. Results: In total, 114 of 19 264 children with a neurological condition had an MI-E device. Seventy-three of 103 eligible children (31 females, 42 males), median (min–max) age of 10 years 1 month (1y 5mo–17y 10mo), reported their MI-E treatment initiation. Overall, 76% reported airway clearance as the main reason to start long-term MI-E. A prophylactic use was mainly reported by children with neuromuscular disorders (NMDs). Prevalence and age at initiation differed by diagnosis. In spinal muscular atrophy and muscular dystrophies, MI-E use was reported in 34% and 7% of children, of whom 83% and 57% respectively received ventilator support. One-third of the MI-E users were children with central nervous system (CNS) conditions, such as cerebral palsy and degenerative disorders, and ventilator support was provided in 31%. The overall use of concomitant ventilatory support among the long-term MI-E users was 56%. Interpretation: The prevalence of MI-E in a neuropaediatric population was 6 per 1000, with two-thirds having NMDs and one-third having conditions of the CNS. The decision to initiate MI-E in children with neurological conditions relies on clinical judgment.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.titlePrevalence of long-term mechanical insufflation-exsufflation in children with neurological conditions: a population-based studyen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.rights.holderCopyright 2021 the authorsen_US
dc.source.journalDevelopmental Medicine & Child Neurologyen_US
dc.identifier.citationDevelopmental Medicine & Child Neurology. 2021, 63 (5), 537-544.en_US

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Navngivelse 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Navngivelse 4.0 Internasjonal