dc.contributor.author | Hov, Brit | |
dc.contributor.author | Andersen, Tiina Maarit | |
dc.contributor.author | Toussaint, Michel | |
dc.contributor.author | Vollsæter, Maria | |
dc.contributor.author | Mikalsen, Ingvild Bruun | |
dc.contributor.author | Indrekvam, Solfrid | |
dc.contributor.author | Hovland, Vegard | |
dc.date.accessioned | 2021-12-08T09:54:40Z | |
dc.date.available | 2021-12-08T09:54:40Z | |
dc.date.created | 2021-04-19T11:48:19Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 0012-1622 | |
dc.identifier.uri | https://hdl.handle.net/11250/2833306 | |
dc.description.abstract | Aim: To determine the prevalence of long-term mechanical insufflation-exsufflation (MI-E) and concomitant mechanical ventilation in children with neurological conditions, with reported reasons behind the initiation of treatment.
Method: This was a population-based, cross-sectional study using Norwegian national registries and a questionnaire.
Results: In total, 114 of 19 264 children with a neurological condition had an MI-E device. Seventy-three of 103 eligible children (31 females, 42 males), median (min–max) age of 10 years 1 month (1y 5mo–17y 10mo), reported their MI-E treatment initiation. Overall, 76% reported airway clearance as the main reason to start long-term MI-E. A prophylactic use was mainly reported by children with neuromuscular disorders (NMDs). Prevalence and age at initiation differed by diagnosis. In spinal muscular atrophy and muscular dystrophies, MI-E use was reported in 34% and 7% of children, of whom 83% and 57% respectively received ventilator support. One-third of the MI-E users were children with central nervous system (CNS) conditions, such as cerebral palsy and degenerative disorders, and ventilator support was provided in 31%. The overall use of concomitant ventilatory support among the long-term MI-E users was 56%.
Interpretation: The prevalence of MI-E in a neuropaediatric population was 6 per 1000, with two-thirds having NMDs and one-third having conditions of the CNS. The decision to initiate MI-E in children with neurological conditions relies on clinical judgment. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.rights | Navngivelse 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/deed.no | * |
dc.title | Prevalence of long-term mechanical insufflation-exsufflation in children with neurological conditions: a population-based study | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright 2021 the authors | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.1111/dmcn.14797 | |
dc.identifier.cristin | 1905047 | |
dc.source.journal | Developmental Medicine & Child Neurology | en_US |
dc.source.pagenumber | 537-544 | en_US |
dc.identifier.citation | Developmental Medicine & Child Neurology. 2021, 63 (5), 537-544. | en_US |
dc.source.volume | 63 | en_US |
dc.source.issue | 5 | en_US |