dc.contributor.author | Vogt, Elinor Margrethe Chelsom | |
dc.contributor.author | Hammerling, Katrin | |
dc.contributor.author | Sorbye, Halfdan | |
dc.contributor.author | Heie, Anette | |
dc.contributor.author | Sulen, André | |
dc.contributor.author | Ueland, Grethe Åstrøm | |
dc.contributor.author | Husebye, Eystein Sverre | |
dc.contributor.author | Methlie, Paal | |
dc.date.accessioned | 2022-03-23T10:56:28Z | |
dc.date.available | 2022-03-23T10:56:28Z | |
dc.date.created | 2022-01-25T14:19:55Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 2052-0573 | |
dc.identifier.uri | https://hdl.handle.net/11250/2987062 | |
dc.description.abstract | Feminizing estrogen-secreting adrenocortical carcinomas (ACCs) are exceedingly rare and carry a poor prognosis. The most common presenting trait is gynecomastia, but enlarged breasts are also a frequent clinical finding in healthy men. Biochemical evaluation may be challenging. As such, there is a high risk of delayed diagnosis and treatment opportunity. Here, we present a case with an estrogen-producing ACC where the abnormal steroid profile obtained at the time of initial workup was essential for the prompt diagnosis. Wider adoption of liquid chromatography mass spectrometry-based steroid assays has potential to improve early diagnosis of feminizing estrogen-secreting ACC. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | BioScientifica | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.title | Feminizing adrenal tumor identified by plasma steroid profiling | en_US |
dc.type | Journal article | en_US |
dc.type | Peer reviewed | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | Copyright the authors 2021 | en_US |
dc.source.articlenumber | 21-0104 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |
dc.identifier.doi | 10.1530/EDM-21-0104 | |
dc.identifier.cristin | 1989599 | |
dc.source.journal | Endocrinology, Diabetes and Metabolism Case Reports | en_US |
dc.identifier.citation | Endocrinology, Diabetes and Metabolism Case Reports. 2021, 2021 (1), 21-0104. | en_US |
dc.source.volume | 2021 | en_US |
dc.source.issue | 1 | en_US |