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dc.contributor.authorEidet, Jon Roger
dc.contributor.authorChen, Xiangjun
dc.contributor.authorRæder, Sten
dc.contributor.authorBadian, Reza
dc.contributor.authorUtheim, Tor Paaske
dc.date.accessioned2022-12-30T13:59:47Z
dc.date.available2022-12-30T13:59:47Z
dc.date.created2022-12-23T11:36:52Z
dc.date.issued2022
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/11250/3040112
dc.description.abstractThe study investigated the seasonal variations of presenting symptoms and signs of dry eye disease (DED) in Norway. 652 consecutive DED patients examined between August 2012 and May 2015 in Oslo, Norway, were included. Presenting symptoms and signs were related to the season according to when each patient was examined. Weather report data from the examination day were compared with the presenting symptoms and signs. Oslo's mean seasonal temperatures during spring, summer, fall, and winter were 6.4 °C, 15.6 °C, 9.3 °C, and − 2.1 °C, respectively. Dry eye severity level and self-reported symptoms measured by the Ocular surface disease index questionnaire did not differ between seasons. Schirmer I was lower during summer than in other seasons (P < 0.01). The percentage of patients with a pathological tear meniscus height (< 0.2 mm) was higher during fall (P < 0.01) and lower during winter (P < 0.05) compared to the other seasons. Signs and symptoms of DED generally did not correlate with weather report data, although intraocular pressure was weakly associated with mean daily air temperature (r = − 0.22; P < 0.001). Neither dry eye severity level nor dry eye symptoms differ between seasons in Oslo, Norway. However, some parameters for assessing DED show seasonal variations (Schirmer I and tear meniscus height), which are essential to consider when examining patients with DED.en_US
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleSeasonal variations in presenting symptoms and signs of dry eye disease in Norwayen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2022 the authorsen_US
dc.source.articlenumber21046en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.1038/s41598-022-25557-9
dc.identifier.cristin2097218
dc.source.journalScientific Reportsen_US
dc.identifier.citationScientific Reports. 2022, 12, 21046.en_US
dc.source.volume12en_US


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