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dc.contributor.authorLam, Holly C. Y.
dc.contributor.authorNeukirch, Catherine
dc.contributor.authorJanson, Christer
dc.contributor.authorGarcia-Aymerich, Judith
dc.contributor.authorClausen, Michael
dc.contributor.authorIdrose, N. Sabrina
dc.contributor.authorDemoly, Pascal
dc.contributor.authorBertelsen, Randi Jacobsen
dc.contributor.authorRuiz, Lidia C.
dc.contributor.authorRaherison, Chantal
dc.contributor.authorJarvis, Deborah L.
dc.date.accessioned2023-11-15T10:45:58Z
dc.date.available2023-11-15T10:45:58Z
dc.date.created2023-06-28T10:27:30Z
dc.date.issued2023
dc.identifier.issn0954-3007
dc.identifier.urihttps://hdl.handle.net/11250/3102689
dc.description.abstractBackground/Objectives: Food hypersensitivity (FHS) is common, but little is known about the factors associated with severe reactions, age of onset and whether sensitization persists. This study examines the factors associated with self-reported severe food reactions, onset age and the changes in prevalence of sensitization to foods over time in an adult sample. Subjects/Methods: We used data from adults taking part in the European Community Respiratory Health Survey (ECRHS) III (2010–2014) who provided information on food hypersensitivity, including symptoms, suspected culprit food and onset age (n = 4865). A subsample from six countries had serum food-specific IgE tested for 25 core foods and also in 10 years earlier (ECRHS II). We applied logistic regression and McNemar’s test for analyses. Results: The prevalence of self-reported FHS was 13.5% at ECRHS III. Of those providing information on symptoms (n = 611), 26.4% reported severe reactions. About 80% of 1033 reported food-specific reactions (reported by 596 participants) began after age 15. History of asthma (odds ratio OR 2.12 95% confidence interval CI 1.13–3.44) and a younger age of onset of FHS (OR 1.02, 95% CI 1.01–1.03, per year) were associated with higher risks of a lifetime experience of severe food reactions. In the subsample with IgE tested in both surveys (n = 1612), the overall prevalence of sensitization to foods did not change over 10 years. Conclusion: Our findings support previous observations of more severe food reactions in people with asthma and that most FHS reported by this sample started after age 15. We found no evidence of changes in the prevalence of sensitization to food in adults followed for 10 years.en_US
dc.language.isoengen_US
dc.publisherSpringer Natureen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleFood hypersensitivity: an examination of factors influencing symptoms and temporal changes in the prevalence of sensitization in an adult sampleen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2023 the authorsen_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.1038/s41430-023-01284-w
dc.identifier.cristin2158971
dc.source.journalEuropean Journal of Clinical Nutritionen_US
dc.source.pagenumber833-840en_US
dc.identifier.citationEuropean Journal of Clinical Nutrition. 2023, 77, 833-840.en_US
dc.source.volume77en_US


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Navngivelse 4.0 Internasjonal
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