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dc.contributor.authorAbbah, Achenyo Peace
dc.contributor.authorXu, Shanshan
dc.contributor.authorJohannessen, Ane
dc.date.accessioned2024-01-17T12:48:33Z
dc.date.available2024-01-17T12:48:33Z
dc.date.created2023-10-06T12:54:53Z
dc.date.issued2023
dc.identifier.issn1932-6203
dc.identifier.urihttps://hdl.handle.net/11250/3112176
dc.description.abstractBackground Several epidemiological studies have examined the risk of asthma and respiratory diseases in association with long-term exposure to outdoor air pollution. However, little is known regarding the adverse effects of long-term exposure to outdoor air pollution on the development of these outcomes in low- and middle-income countries (LMICs). Our study aims to investigate the association between long-term exposure to outdoor air pollution and asthma and respiratory diseases in LMICs through a systematic review with meta-analysis. Methods This systematic review and meta-analysis will follow the PRISMA (Preferred Reporting for Systematic Reviews and Meta-Analyses) checklist and flowchart guidelines. The inclusion criteria that will be used in our study are 1) Original research articles with full text in English; 2) Studies including adult humans; 3) Studies with long-term air pollution assessment in LMICs, air pollutants including nitrogen oxide (NO2), sulfur oxide (SO2), particulate matter (PM2.5 and PM10), carbon monoxide (CO) and ozone (O3); 4) cohort and cross-sectional studies; 5) Studies reporting associations between air pollution and asthma and respiratory symptoms. A comprehensive search strategy will be used to identify studies published up till August 2022 and indexed in Embase, Medline, and Web of Science. Three reviewers will independently screen records retrieved from the database searches. Where there are enough studies with similar exposure and outcomes, we will calculate, and report pooled effect estimates using meta-analysis. Systematic review registration PROSPERO CRD42022311326. Discussion Findings from the health effects of long-term exposure to outdoor air pollution may be of importance for policymakers. This review will also identify any gaps in the current literature on this topic in LMICs and provide direction for future research.en_US
dc.language.isoengen_US
dc.publisherPLoSen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleLong-term exposure to outdoor air pollution and asthma in low-and middle-income countries: A systematic review protocolen_US
dc.typeJournal articleen_US
dc.typePeer revieweden_US
dc.description.versionpublishedVersionen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.source.articlenumbere0288667en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1
dc.identifier.doi10.1371/journal.pone.0288667
dc.identifier.cristin2182443
dc.source.journalPLOS ONEen_US
dc.identifier.citationPLOS ONE. 2023, 18 (7), e0288667.en_US
dc.source.volume18en_US
dc.source.issue7en_US


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