• Conditioned Medium from Bone Marrow Mesenchymal Stem Cells Restored Oxidative Stress-Related Impaired Osteogenic Differentiation 

      Saleem, Ragda; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Elnour, Rammah; Berggreen, Ellen; Mustafa, Kamal Babikeir Elnour; Al-Sharabi, Niyaz Abdulbaqi Abdulmajid (Journal article; Peer reviewed, 2021)
      Oxidative stress from high levels of intracellular reactive oxygen species (ROS) has been linked to various bone diseases. Previous studies indicate that mesenchymal stem cells (MSC) secrete bioactive factors (conditioned ...
    • Influence of Bone Substitutes on Mesenchymal Stromal Cells in an Inflammatory Microenvironment 

      Shanbhag, Siddharth; Rana, Neha; Suliman, Salwa; Idris, Shaza Bushra Mohamed; Mustafa, Kamal Babikeir Elnour; Stavropoulos, Andreas (Journal article; Peer reviewed, 2022)
      Bone regeneration is driven by mesenchymal stromal cells (MSCs) via their interactions with immune cells, such as macrophages (MPs). Bone substitutes, e.g., bi-calcium phosphates (BCPs), are commonly used to treat bone ...
    • Label-free monitoring of uptake and toxicity of endoprosthetic wear particles in human cell cultures 

      Jonitz-Heincke, Anika; Tillmann, Jenny; Ostermann, Melanie; Springer, Armin; Bader, Rainer; Høl, Paul Johan; Cimpan, Mihaela Roxana (Peer reviewed; Journal article, 2018)
      The evaluation of the biological effects of endoprosthetic wear particles on cells in vitro relies on a variety of test assays. However, most of these methods are susceptible to particle-induced interferences; therefore, ...
    • Proteomic Analysis of Mesenchymal Stromal Cells Secretome in Comparison to Leukocyte- and Platelet-Rich Fibrin 

      Al-Sharabi, Niyaz Abdulbaqi Abdulmajid; Gruber, Reinhard; Sanz, Mariano; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Kristoffersen, Einar Klæboe; Mustafa, Kamal Babikeir Elnour; Shanbhag, Siddharth (Journal article; Peer reviewed, 2023)
      Secretomes of mesenchymal stromal cells (MSCs) are emerging as a novel growth factor (GF)-based strategy for periodontal and bone regeneration. The objective of this study was to compare the secretome of human bone marrow ...
    • Role of SNAREs and Rabs in Myelin Regulation 

      Margiotta, Azzurra (Journal article; Peer reviewed, 2023-06-05)
      The myelin sheath is an insulating layer around the nerves of the brain and spinal cord which allows a fast and efficient nerve conduction. Myelin is made of protein and fatty substances and gives protection for the ...