• A cellular and molecular analysis of SoxB-driven neurogenesis in a cnidarian 

      Chrysostomou, Eleni; Flici, Hakima; Gornik, Sebastian G.; Salinas-Saavedra, Miguel; Gahan, James Michael; McMahon, Emma T.; Thompson, Kerry; Hanley, Shirley; Kilcoyne, Michelle; Schnitzler, Christine E.; Gonzalez, Paul; Baxevanis, Andreas D.; Frank, Uri (Journal article; Peer reviewed, 2022)
      Neurogenesis is the generation of neurons from stem cells, a process that is regulated by SoxB transcription factors (TFs) in many animals. Although the roles of these TFs are well understood in bilaterians, how their ...
    • Supracellular organization confers directionality and mechanical potency to migrating pairs of cardiopharyngeal progenitor cells 

      Bernadskaya, Yelena Y.; Yue, Haicen; Copos, Calina; Christiaen, Lionel; Mogilner, Alex (Journal article; Peer reviewed, 2021)
      Physiological and pathological morphogenetic events involve a wide array of collective movements, suggesting that multicellular arrangements confer biochemical and biomechanical properties contributing to tissue-scale ...
    • Transcriptional adaptation in caenorhabditis elegans 

      Serobyan, Vahan; Kontarakis, Zacharias; El-Brolosy, Mohamed A.; Welker, Jordan M.; Tolstenkov, Oleg; Saadeldein, Amr M.; Retzer, Nicholas; Gottschalk, Alexander; Wehman, Ann M; Stainier, Didier YR (Journal article; Peer reviewed, 2020-01)
      Transcriptional adaptation is a recently described phenomenon by which a mutation in one gene leads to the transcriptional modulation of related genes, termed adapting genes. At the molecular level, it has been proposed ...
    • The visual pigment xenopsin is widespread in protostome eyes and impacts the view on eye evolution 

      Hausen, Harald; Döring, Clemens; Kumar, Suman; Tumu, Sharat Chandra; Kourtesis, Ioannis (Journal article; Peer reviewed, 2020)
      Photoreceptor cells in the eyes of Bilateria are often classified into microvillar cells with rhabdomeric opsin and ciliary cells with ciliary opsin, each type having specialized molecular components and physiology. First ...