Now showing items 332-351 of 649

    • Minimum Fill-in of Sparse Graphs: Kernelization and Approximation 

      Fomin, Fedor; Geevarghese, Philip; Villanger, Yngve (Conference object; Peer reviewed; Journal article, 2011)
      The Minimum Fill-in problem is to decide if a graph can be triangulated by adding at most k edges. The problem has important applications in numerical algebra, in particular in sparse matrix computations. We develop ...
    • A minimum requiring angle trisection 

      Steihaug, Trond; Rogers, D. G. (Peer reviewed; Journal article, 2009)
    • Model Checking Healthcare Workflows Using Alloy 

      Wang, Xiaoliang; Rutle, Adrian (Conference object; Peer reviewed, 2014)
      Workflows are used to organize business processes, and workflow management tools are used to guide users in which order these processes should be performed. These tools increase organizational efficiency and enable users ...
    • Model Checking with the Sweep-Line Method 

      Lilleskare, Andreas (Master thesis, 2017-06-21)
      Explicit-state model checking is a formal software verification technique that differs from peer review and unit testing, in that model checking does an exhaustive state space search. With model checking one takes a system ...
    • A model driven approach to the design of a gamified e-learning system for clinical guidelines 

      Nyameino, Job; Rabbi, Fazle; Mughal, Khalid Azim; Were, Martin C; Lamo, Yngve (Peer reviewed; Journal article, 2019-08-21)
      Clinical practice guidelines (CPGs) are indispensable in the practice of evidence-based medicine. However, the cost of effective CPG dissemination strategies is prohibitive and not cost-effective. Therefore, scalable ...
    • A model for optimal fleet composition of vessels for offshore wind farm maintenance 

      Gutierrez-Alcoba, Alejandro; Ortega, Gloria; Hendrix, Eligius M.T.; Halvorsen-Weare, Elin Espeland; Haugland, Dag (Peer reviewed; Journal article, 2017)
      We present a discrete optimisation model that chooses an optimal fleet of vessels to support maintenance operations at Offshore Wind Farms (OFWs). The model is presented as a bi-level problem. On the first (tactical) level, ...
    • A Model of Type Theory in Cubical Sets 

      Bezem, Marcus Aloysius; Coquand, Thierry; Huber, Simon (Peer reviewed; Journal article, 2014)
      We present a model of type theory with dependent product, sum, and identity, in cubical sets. We describe a universe and explain how to transform an equivalence between two types into an equality. We also explain how to ...
    • Model-based clustering of multi-tissue gene expression data 

      Erola, Pau; Björkegren, Johan L.M.; Michoel, Tom Luk Robert (Journal article; Peer reviewed, 2020)
      Motivation Recently, it has become feasible to generate large-scale, multi-tissue gene expression data, where expression profiles are obtained from multiple tissues or organs sampled from dozens to hundreds of individuals. ...
    • Model-based exploration of the impact of glucose metabolism on the estrous cycle dynamics in dairy cows 

      Omari, Mohamed; Lange, Alexander; Plöntzke, Julia; Röblitz, Susanna (Peer reviewed; Journal article, 2020)
      Background: Nutrition plays a crucial role in regulating reproductive hormones and follicular development in cattle. This is visible particularly during the time of negative energy balance at the onset of milk production ...
    • Model-based Visualization for Medical Education and Training 

      Smit, Noeska Natasja; Lawonn, Kai; Kraima, Annelot; DeRuiter, Marco; Bruckner, Stefan; Eisemann, Elmar; Vilanova, Anna (Peer reviewed; Journal article, 2019)
      Anatomy, or the study of the structure of the human body, is an essential component of medical education. Certain parts of human anatomy are considered to be more complex to understand than others, due to a multitude of ...
    • Model-Driven Automatic Question Generation for a Gamified Clinical Guideline Training System 

      Nyameino, Job Nyangena; Ebbesvik, Ben-Richard Sletten; Rabbi, Fazle; Were, Martin C.; Lamo, Yngve (Journal article; Peer reviewed, 2020)
      Clinical practice guidelines (CPGs) are a cornerstone of modern medical practice since they summarize the vast medical literature and provide care recommendations based on the current best evidence. However, there are ...
    • Modeling of Multivalent Ligand-Receptor Binding Measured by kinITC 

      Erlekam, Franziska; Igde, Sinaida; Röblitz, Susanna; Hatmann, Laura; Weber, Marcus (Peer reviewed; Journal article, 2019)
      In addition to the conventional Isothermal Titration Calorimetry (ITC), kinetic ITC (kinITC) not only gains thermodynamic information, but also kinetic data from a biochemical binding process. Moreover, kinITC gives insights ...
    • Modelling migration patterns of fish using depth and temperature preferences 

      Natvig, Erik (Master thesis, 2012-04-27)
      Time series of depth and temperature derived from electronic tagging of fish have been used to construct a stochastic model that aims at capturing main characteristics of the observations. Mixed Ornstein-Uhlenbeck process ...
    • Modelling the structure, function and evolution of Polycomb/Trithorax Response Elements 

      Bredesen, Bjørn Andre (Doctoral thesis, 2020-11-20)
      The correct development of animals and plants depends on carefully coordinated gene regulation. Polycomb/Trithorax Group (PcG/TrxG) proteins are conserved epigenetic regulators that are recruited to Polycomb/Trithorax ...
    • Models and Solution Methods for the Pooling Problem 

      Alfaki, Mohammed (Doctoral thesis, 2012-06-18)
      Pipeline transportation of natural gas is largely affected by restrictions regarding gas quality imposed by the market and the actual quality of the gas produced at sources. From the sources, gas flow streams of unequal ...
    • Modification to planarity is fixed parameter tractable 

      Fomin, Fedor; Golovach, Petr; Thilikos, Dimitrios M (Peer reviewed; Journal article, 2019)
      A replacement action is a function L that maps each k-vertex labeled graph to another k-vertex graph. We consider a general family of graph modification problems, called L-Replacement to C, where the input is a graph G and ...
    • Modulation of Transcriptional and Inflammatory Responses in Murine Macrophages by the Mycobacterium tuberculosis Mammalian Cell Entry (Mce) 1 Complex 

      Stavrum, Ruth; Stavrum, Anne-Kristin; Valvatne, Håvard; Riley, Lee W.; Ulvestad, Elling; Jonassen, Inge; Assmus, Jørg; Doherty, Tanya Mark; Grewal, Harleen M. S. (Peer reviewed; Journal article, 2011-10-24)
      The outcome of many infections depends on the initial interactions between agent and host. Aiming at elucidating the effect of the M. tuberculosis Mce1 protein complex on host transcriptional and immunological responses ...
    • Molecular mechanisms of adaptation emerging from the physics and evolution of nucleic acids and proteins 

      Goncearenco, Alexander; Ma, Binguang; Berezovsky, Igor (Peer reviewed; Journal article, 2014)
      DNA, RNA and proteins are major biological macromolecules that coevolve and adapt to environments as components of one highly interconnected system. We explore here sequence/structure determinants of mechanisms of adaptation ...
    • Monte Carlo Study of the Formation and Conformational Properties of Dimers of Aβ42 Variants 

      Mitternacht, Simon; Staneva, Iskra; Härd, Torleif; Irbäck, Anders (Peer reviewed; Journal article, 2011)
      Small soluble oligomers, and dimers in particular, of the amyloid β-peptide (Aβ) are believed to play an important pathological role in Alzheimer's disease. Here, we investigate the spontaneous dimerization of Aβ42, with ...