• Blind search for post-translational modifications and amino acid substitutions using peptide mass fingerprints from two proteases 

      Barsnes, Harald; Mikalsen, Svein-Ole; Eidhammer, Ingvar (Peer reviewed; Journal article, 2008-12-19)
      Background: Mass spectrometric analysis of peptides is an essential part of protein identification and characterization, the latter meaning the identification of modifications and amino acid substitutions. There are two ...
    • Detecting single amino acids and small peptides by combining isobaric tags and peptidomics 

      Burger, Bram; Lereim, Ragnhild Reehorst; Berven, Frode; Barsnes, Harald (Peer reviewed; Journal article, 2019)
      Single amino acids and small endogenous peptides play important roles in maintaining a properly functioning organism. These molecules are however currently only routinely identified in targeted approaches. In a small ...
    • Development of Tools for Analyzing and Sharing Proteomics Data 

      Barsnes, Harald (Doctoral thesis, 2010-03-22)
    • MassSorter: a tool for administrating and analyzing data from mass spectrometry experiments on proteins with known amino acid sequences 

      Barsnes, Harald; Mikalsen, Svein-Ole; Eidhammer, Ingvar (Peer reviewed; Journal article, 2006-01-26)
      Background: Proteomics is the study of the proteome, and is critical to the understanding of cellular processes. Two central and related tasks of proteomics are protein identification and protein characterization. Many ...
    • OLS Dialog: An open-source front end to the Ontology Lookup Service 

      Barsnes, Harald; Côté, Richard G.; Eidhammer, Ingvar; Martens, Lennart (Peer reviewed; Journal article, 2010-01-17)
      Background: With the growing amount of biomedical data available in public databases it has become increasingly important to annotate data in a consistent way in order to allow easy access to this rich source of information. ...
    • The Ontology Lookup Service: bigger and better 

      Côté, Richard G.; Reisinger, Florian; Martens, Lennart; Barsnes, Harald; Vizcaíno, Juan Antonio; Hermjakob, Henning (Peer reviewed; Journal article, 2010-05-11)
      The Ontology Lookup Service (OLS; http://www.ebi .ac.uk/ols) has been providing several means to query, browse and navigate biomedical ontologies and controlled vocabularies since it first went into production 4 years ago, ...
    • Protease-dependent fractional mass and peptide properties 

      Barsnes, Harald; Eidhammer, Ingvar; Cruciani, Véronique; Mikalsen, Svein-Ole (Peer reviewed; Journal article, 2008-09-22)
      Mass spectrometric analyses of peptides mainly rely on cleavage of proteins with proteases that have a defined specificity. The specificities of the proteases imply that there is not a random distribution of amino acids ...
    • The Proteomics Identifications database: 2010 update 

      Vizcaíno, Juan Antonio; Côté, Richard G.; Reisinger, Florian; Barsnes, Harald; Foster, JM; Rameseder, Jonathan; Hermjakob, Henning; Martens, Lennart (Peer reviewed; Journal article, 2009-11-11)
      The Proteomics Identifications database (PRIDE, http://www.ebi.ac.uk/pride) at the European Bioinformatics Institute has become one of the main repositories of mass spectrometry-derived proteomics data. For the last 2 ...
    • ThermoRawFileParser: Modular, Scalable, and Cross-Platform RAW File Conversion 

      Hulstaert, Niels; Shofstahl, Jim; Sachsenberg, Timo; Walzer, Mathias; Barsnes, Harald; Martens, Lennart; Perez-Riverol, Yasset (Journal article; Peer reviewed, 2020)
      The field of computational proteomics is approaching the big data age, driven both by a continuous growth in the number of samples analyzed per experiment as well as by the growing amount of data obtained in each analytical ...