Browsing Department of Informatics by Journals "Journal of Theoretical Biology"
Now showing items 1-4 of 4
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Bifurcation and sensitivity analysis reveal key drivers of multistability in a model of macrophage polarization
(Journal article; Peer reviewed, 2020)In this paper, we present and analyze a mathematical model for polarization of a single macrophage which, despite its simplicity, exhibits complex dynamics in terms of multistability. In particular, we demonstrate that an ... -
Hormonal regulation of ovarian follicle growth in humans: Model-based exploration of cycle variability and parameter sensitivities
(Journal article; Peer reviewed, 2022)We present a modelling and simulation framework for the dynamics of ovarian follicles and key hormones along the hypothalamic-pituitary–gonadal axis throughout consecutive human menstrual cycles. All simulation results ... -
Macrophage phenotype transitions in a stochastic gene-regulatory network model
(Journal article; Peer reviewed, 2023)Polarization is the process by which a macrophage cell commits to a phenotype based on external signal stimulation. To know how this process is affected by random fluctuations and events within a cell is of utmost importance ... -
Population dynamic regulators in an empirical predator-prey system
(Journal article; Peer reviewed, 2021)Capelin (Mallotus villosus) is a short-lived (1–4 years) fish species, that plays a crucial role by dominating the intermediate trophic level in the Barents Sea. Several episodes of extreme biomass decline (collapse) have ...