Blar i Department of Informatics på tidsskrift "Nucleic Acids Research"
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CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing
(Peer reviewed; Journal article, 2019-07-02)The CRISPR–Cas system is a powerful genome editing tool that functions in a diverse array of organisms and cell types. The technology was initially developed to induce targeted mutations in DNA, but CRISPR–Cas has now been ... -
JASPAR 2014: An extensively expanded and updated open-access database of transcription factor binding profiles
(Peer reviewed; Journal article, 2014-01)JASPAR (http://jaspar.genereg.net) is the largest open-access database of matrix-based nucleotide profiles describing the binding preference of transcription factors from multiple species. The fifth major release greatly ... -
Molecular mechanisms of adaptation emerging from the physics and evolution of nucleic acids and proteins
(Peer reviewed; Journal article, 2014)DNA, RNA and proteins are major biological macromolecules that coevolve and adapt to environments as components of one highly interconnected system. We explore here sequence/structure determinants of mechanisms of adaptation ... -
The Ontology Lookup Service: bigger and better
(Peer reviewed; Journal article, 2010-05-11)The Ontology Lookup Service (OLS; http://www.ebi .ac.uk/ols) has been providing several means to query, browse and navigate biomedical ontologies and controlled vocabularies since it first went into production 4 years ago, ...