Blar i Department of Informatics på tidsskrift "eLIFE"
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Extensive intraspecies cryptic variation in an ancient embryonic gene regulatory network
(Peer reviewed; Journal article, 2019-08-15)Innovations in metazoan development arise from evolutionary modification of gene regulatory networks (GRNs). We report widespread cryptic variation in the requirement for two key regulatory inputs, SKN-1/Nrf2 and MOM-2/Wnt, ... -
Rapid genome editing by CRISPR-Cas9-POLD3 fusion
(Journal article; Peer reviewed, 2021)Precision CRISPR gene editing relies on the cellular homology-directed DNA repair (HDR) to introduce custom DNA sequences to target sites. The HDR editing efficiency varies between cell types and genomic sites, and the ...