Browsing Department of Chemistry by Title
Now showing items 398-417 of 448
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Synthesis of imidazole core based small molecules for the treatment of SMA
(Master thesis, 2019-08-29) -
Synthesis of penta-fold twinned Pd-Au-Pd segmental nanorods for in situ monitoring catalytic reaction
(Journal article; Peer reviewed, 2020)Multimetallic nanomaterials have many applications. The controlled synthesis of multimetallic nanomaterials is highly desired. We report a study on using penta-fold twinned (PFT) Au nanorods (NRs) as seeds to synthesize ... -
Synthesis of Some Nitrogen Heterocycles of Medicinal Relevance
(Doctoral thesis, 2012-04-18)In the first part of the project, two highly functionalized terminal alkynes, 3,3,4,4- tetraethoxybut-1-yne (TEB) and 1,1-diethoxy-but-3-yn-2-one (keto-TEB) have been used for the synthesis of 1,4-disubstituted 1,2,3-triazoles. ... -
Synthesis of substituted imidazoles that stabilizes Survival Motor Neuron Protein for treatment of Spinal Muscular Atrophy
(Master thesis, 2019-08-31)Spinal muscular atrophy (SMA) is a common autosomal recessive disorder and the leading cause of infant mortality. Patients with this disorder are missing the SMN1 gene that is producing 80-90 % of the Spinal motor neuron ... -
Synthesis, Characterization and Catalytic Applications of N-Heterocyclic Carbene Based Vanadium Complexes.
(Master thesis, 2022-05-31)New tri- and tetradentate O-functionalized NHC oxo- and imido vanadium complexes have been synthesized and characterized. The complexes were preliminary tested for catalytic activity towards coupling of CO2 and epoxides ... -
Synthetic studies toward [18F]-fluorination of solid-supported silyl ethers
(Doctoral thesis, 2023-05-25)Molekylær avbildning er definert som visualisering av in vivo biologiske prosesser på molekylært- eller cellulært nivå. Dette krever bruk av prober og kan gi anatomisk samt funksjonell informasjon. Molekylær avbildning ... -
TAT-Modified Gold Nanoparticles Enhance the Antitumor Activity of PAD4 Inhibitors
(Journal article; Peer reviewed, 2020)Purpose: Histone citrullination by peptidylarginine deiminases 4 (PAD4) regulates the gene expression of tumor suppressor. In our previously study, YW3-56 (356) was developed as a potent PAD4 inhibitor for cancer therapy ... -
Technetium-99 (99Tc) in the North and Nordic Seas – the present status (2010) and a compilation of the Institute of Marine Research’s monitoring data (2003-2009)
(Master thesis, 2011-04-26)Technetium-99 (99Tc) is an anthropogenic, pure β-emitting (Emax = 292 keV) radionuclide with a half-life of 2.13 · 10^5 years. It is present in the marine environment primarily due to discharges from nuclear fuel reprocessing ... -
Tegn på forståelse av kjemi i elevrapporter: En undersøkelse av elevrapporter i programfag i kjemi
(Master thesis, 2018-06-26)Praktisk arbeid i realfagsundervisning er et tema som er mye diskutert i forskningen. Særlig problemstillinger som omhandler læringsutbyttet av praktisk arbeid er mye forsket på, og i den sammenheng også rapportene som ... -
A Theoretical Study of Cr/oxide Catalysts for Dehydrogenation of Short Alkanes
(Doctoral thesis, 2006-10-27)Natural gas reserves are being produced at increasing rates world wide, thus providing an abundance of short-alkane feedstock for the petrochemical industry. Effective routes to selective activation of short alkanes may ... -
Theory-Based Mechanistic Insight as Stepping Stone for Catalyst Development in Olefin Polymerization
(Doctoral thesis, 2011-09-29) -
Thermal stability of polyphenols and carotenoids from Laminaria hyperborea
(Master thesis, 2024-06-03)The green shift, and the focus on an increased blue bioeconomy, has stimulated the growth of sustainable production lines for marine bioactive products for food-, feed-, cosmetics-, and -pharmaceutical industries. Norway ... -
TiO2/Fe2O3 heterostructures with enhanced photocatalytic reduction of Cr(VI) under visible light irradiation
(Peer reviewed; Journal article, 2019-07-23)We report a study on the synthesis of TiO2/Fe2O3 (TF) nanocomposites and their photocatalytic performance under visible-light irradiation. The characterization of structure and morphology shows that hematite Fe2O3 was ... -
Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei
(Journal article; Peer reviewed, 2023)Microplastics (MPs) pose one of the major environmental threats to marine organisms and ecosystems on a global scale. Although many marine crustaceans are highly susceptible to MPs pollution, the toxicological effects and ... -
Total Synthesis of Phorbazole B
(Journal article; Peer reviewed, 2020)Phorbazoles are polychlorinated heterocyclic secondary metabolites isolated from a marine sponge and several of these natural products have shown inhibitory activity against cancer cells. In this work, a synthesis of the ... -
Totalkvikksølv og metylkvikksølv i filet og lever av brosme fiska i Boknafjorden, samanlikna med Hardangerfjorden og Lofoten
(Master thesis, 2014-11-20)Det har i lang tid vore kjend at Hardangerfjorden er forureina, spesielt innerst i fjorden. Tidlegare masteroppgåver som er blitt gjort ved NIFES har funne kvikksølvkonsentrasjonar i brosme (Brosme brosme) frå Hardangerfjorden ... -
Toward E-selective Olefin Metathesis: Computational Design and Experimental Realization of Ruthenium Thio-Indolate Catalysts
(Journal article; Peer reviewed, 2021)The selective transformation of 1-alkenes into E-olefins is a long-standing challenge in olefin metathesis. Density functional theory (DFT) calculations predict high E-selectivity for catalysts incorporating a bidentate, ... -
Towards a Synthesis of the Marine Alkaloid Naamidine B
(Master thesis, 2014-09-15) -
Towards the Synthesis of β-Hydroxy 1,3-Dithiane Derivatives
(Master thesis, 2019-10-03)The β-hydroxy dithiane, 3-(1,3-dithiane-2-yl)-1,1-diethoxypropan-2-ol, was synthesized from the versatile synthon 3,3,4,4-tetraethoxybut-1-yne (TEB). 1,1-Diethoxy-3-(2-methyl-1,3- dithian-2-yl)propan-2-ol was successfully ... -
Toxicity prediction using target, interactome, and pathway profiles as descriptors
(Journal article; Peer reviewed, 2023)In silico methods are essential to the safety evaluation of chemicals. Computational risk assessment offers several approaches, with data science and knowledge-based methods becoming an increasingly important sub-group. ...