Browsing Department of Chemistry by Title

Selective rearrangement of terminal epoxides into methylketones catalysed by a nucleophilic rhodium-NHC-pincer complex

Jurgens, Eva; Wucher, Barbara; Rominger, Frank; Törnroos, Karl Wilhelm; Kunz, Doris (Peer reviewed; Journal article, 2014-12-22)

An efficient RhI–NHC–pincer catalyst for the highly regioselective Meinwald rearrangement of monoalkylated epoxides into methylketones under mild conditions is presented. The nucleophilic epoxide opening is assisted by ...

Selenium Speciation in Animal Feeds and Fish Tissues by HPLC ICP-MS – Validation and Application of an Analytical Method

Hanif, Kashif (Master thesis, 2023-09-30)

Selenium (Se) is essential for human and animal health and crucial for selenoprotein synthesis with diverse biological roles. It's mainly sourced from animal feed, particularly fish feed, with fishmeal and marine by-products ...

Sensory and physicochemical properties of enzymatic protein hydrolysates : Influence of raw material, protease, and downstream processing

Steinsholm, Silje (Doctoral thesis, 2021-04-12)

The world aquaculture, fisheries and poultry sectors generate large amounts of residual raw materials, such as heads, backbones, and carcasses. Almost 85% of the residual materials from Norwegian aquaculture and fisheries ...

Serum fatty acid and lipoprotein subclass concentrations and their associations in prepubertal healthy Norwegian children

Rajalahti, Tarja; Lin, Chenchen; Mjøs, Svein Are; Kvalheim, Olav Martin (Peer reviewed; Journal article, 2016-03)

Introduction The lipid metabolism is one of the most important and complex processes in the body. Serum concentrations of 18 fatty acids (FAs) and 24 lipoprotein features, i.e. concentrations of lipoprotein main and ...

Short and Modular Synthesis of Substituted 2‑Aminopyrroles

Diana-Rivero, Raquel; Halsvik, Beate; Garciá Tellado, Fernando; Tejedor, David (Journal article; Peer reviewed, 2021)

We herein describe a simple and metal-free domino methodology to synthesize 2-aminopyrroles from alkynyl vinyl hydrazides. The domino reaction involves a novel propargylic 3,4-diaza-Cope rearrangement and a tandem ...

Silica-supported Z-selective Ru olefin metathesis catalysts

Renom-Carrasco, Marc; Mania, Philipp; Sayah, Reine; Veyre, Laurent; Occhipinti, Giovanni; Jensen, Vidar Remi; Thieuleux, Chloé (Peer reviewed; Journal article, 2020)

Recently reported thiolate-coordinated ruthenium alkylidene complexes show promise in Z-selective and stereoretentive olefin metathesis reactions. Herein we describe the immobilization of three Ru complexes containing a ...

Similarity-Based Methods and Machine Learning Approaches for Target Prediction in Early Drug Discovery: Performance and Scope

Mathai, Neann Sarah; Kirchmair, Johannes (Journal article; Peer reviewed, 2020-05)

Computational methods for predicting the macromolecular targets of drugs and drug-like compounds have evolved as a key technology in drug discovery. However, the established validation protocols leave several key questions ...

Simulating Life at the Periphery: Mechanisms of Membrane Binding and Cargo Extraction by Lipid Transfer Proteins

Talandashti, Reza (Doctoral thesis, 2025-01-09)

Biologiske membraner er svært sofistikerte strukturer som består av tusenvis av forskjellige lipidtyper. Deres mekaniske egenskaper bestemmes hovedsakelig av lipidkomposisjonen, noe som gjør det avgjørende for celler å ...

Skin Doctor: Machine learning models for skin sensitization prediction that provide estimates and indicators of prediction reliability

Wilm, Anke; Stork, Conrad; Bauer, Christoph; Schepky, Andreas; Kühnl, Jochen; Kirchmair, Johannes (Peer reviewed; Journal article, 2019-09-28)

The ability to predict the skin sensitization potential of small organic molecules is of high importance to the development and safe application of cosmetics, drugs and pesticides. One of the most widely accepted methods ...

Smart Surfaces: Design, Structuring and Characterization

Askeland, Simen Hjellvik (Master thesis, 2016-06-02)

Solid-State NMR Study of Drug Interaction with Phospholipid Bilayers Chlorpromazine, olanzapine and articaine interacting with saturated and unsaturated phosphatidylserines and saturated phosphatidylcholines

Song, Chen (Doctoral thesis, 2007-08-28)

Solid-State NMR Validation of OPLS4: Structure of PC-Lipid Bilayers and Its Modulation by Dehydration

Kurki, Milla; Nesterenko, Alexey M.; Alsaker, Nicolai E.; Ferreira, Tiago M.; Kyllönen, Sami; Poso, Antti; Bartos, Piia; Miettinen, Markus S. (Journal article; Peer reviewed, 2024)

Atomistic molecular dynamics (MD) simulations are a much-used tool for investigating the structure and dynamics of biomembranes with atomic resolution. The validity of the representations obtained is determined by the ...

Solubilization of medium-chained alcohols in some ENORDET O series surfactants

Sævland, Daniel (Master thesis, 2013-10-23)

Primary to tertiary pentanol and -hexanol in Shell Chemicals' ENORDET O series IOS 1923, and for primary pentanol in IOS 2024, have been investigated by a thermodynamic approach. Standard partial molar volume and isentropic ...

Solvolytic lignin degradation in an alcohol / formic acid medium - Analysis of the reaction system and products by means of kinetic modelling and chemometrics

Gasson, James Richard (Doctoral thesis, 2012-10-04)

Lignocellulosic biomass has been identified as an abundant renewable resource to produce sustainable alternatives for conventional fossil fuels for the transport sector as well as selected bio-materials and chemicals. ...